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Sodium chloride in the tumor microenvironment enhances T cell metabolic fitness and cytotoxicity.
Soll D, Chu CF, Sun S, Lutz V, Arunkumar M, Gachechiladze M, Schäuble S, Alissa-Alkhalaf M, Nguyen T, Khalil MA, Garcia-Ribelles I, Mueller M, Buder K, Michalke B, Panagiotou G, Ziegler-Martin K, Benz P, Schatzlmaier P, Hiller K, Stockinger H, Luu M, Schober K, Moosmann C, Schamel WW, Huber M, Zielinski CE. Soll D, et al. Among authors: benz p. Nat Immunol. 2024 Oct;25(10):1830-1844. doi: 10.1038/s41590-024-01918-6. Epub 2024 Aug 28. Nat Immunol. 2024. PMID: 39198632 Free PMC article.
Microbial metabolite-guided CAR T cell engineering enhances anti-tumor immunity via epigenetic-metabolic crosstalk.
Staudt S, Nikolka F, Perl M, Franz J, Leblay N, Yuan XK, Warmuth L, Fantes MA, Skorupskaitė A, Fei T, Bromberg M, Martin-Uriz PS, Rodriguez-Madoz JR, Ziegler-Martin K, Gholam NA, Benz P, Tran PH, Freitag F, Riester Z, Stein-Thoeringer C, Schmitt M, Kleigrewe K, Weber J, Mangold K, Einsele H, Prosper F, Ellmeier W, Busch D, Visekruna A, Slingerland J, Shouval R, Hiller K, van den Brink M, Pausch P, Neri P, Hudecek M, Poeck H, Luu M. Staudt S, et al. Among authors: benz p. bioRxiv [Preprint]. 2024 Sep 13:2024.08.19.608538. doi: 10.1101/2024.08.19.608538. bioRxiv. 2024. PMID: 39314273 Free PMC article. Preprint.
85 results