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Inhibition of TOPORS ubiquitin ligase augments the efficacy of DNA hypomethylating agents through DNMT1 stabilization.
Kaito S, Aoyama K, Oshima M, Tsuchiya A, Miyota M, Yamashita M, Koide S, Nakajima-Takagi Y, Kozuka-Hata H, Oyama M, Yogo T, Yabushita T, Ito R, Ueno M, Hirao A, Tohyama K, Li C, Kawabata KC, Yamaguchi K, Furukawa Y, Kosako H, Yoshimi A, Goyama S, Nannya Y, Ogawa S, Agger K, Helin K, Yamazaki S, Koseki H, Doki N, Harada Y, Harada H, Nishiyama A, Nakanishi M, Iwama A. Kaito S, et al. Among authors: ueno m. Nat Commun. 2024 Aug 28;15(1):7359. doi: 10.1038/s41467-024-50498-4. Nat Commun. 2024. PMID: 39198387 Free PMC article.
RHEB is a potential therapeutic target in T cell acute lymphoblastic leukemia.
Pham LT, Peng H, Ueno M, Kohno S, Kasada A, Hosomichi K, Sato T, Kurayoshi K, Kobayashi M, Tadokoro Y, Kasahara A, Shoulkamy MI, Xiao B, Worley PF, Takahashi C, Tajima A, Hirao A. Pham LT, et al. Among authors: ueno m. Biochem Biophys Res Commun. 2022 Sep 17;621:74-79. doi: 10.1016/j.bbrc.2022.06.089. Epub 2022 Jun 30. Biochem Biophys Res Commun. 2022. PMID: 35810594
Abnormal blood vessel development in mice lacking presenilin-1.
Nakajima M, Yuasa S, Ueno M, Takakura N, Koseki H, Shirasawa T. Nakajima M, et al. Among authors: ueno m. Mech Dev. 2003 Jun;120(6):657-67. doi: 10.1016/s0925-4773(03)00064-9. Mech Dev. 2003. PMID: 12834865 Free article.
Association of a murine leukaemia stem cell gene signature based on nucleostemin promoter activity with prognosis of acute myeloid leukaemia in patients.
Ali MA, Naka K, Yoshida A, Fuse K, Kasada A, Hoshii T, Tadokoro Y, Ueno M, Ohta K, Kobayashi M, Takahashi C, Hirao A. Ali MA, et al. Among authors: ueno m. Biochem Biophys Res Commun. 2014 Jul 18;450(1):837-43. doi: 10.1016/j.bbrc.2014.06.066. Epub 2014 Jun 21. Biochem Biophys Res Commun. 2014. PMID: 24960197
Spred1 Safeguards Hematopoietic Homeostasis against Diet-Induced Systemic Stress.
Tadokoro Y, Hoshii T, Yamazaki S, Eto K, Ema H, Kobayashi M, Ueno M, Ohta K, Arai Y, Hara E, Harada K, Oshima M, Oshima H, Arai F, Yoshimura A, Nakauchi H, Hirao A. Tadokoro Y, et al. Among authors: ueno m. Cell Stem Cell. 2018 May 3;22(5):713-725.e8. doi: 10.1016/j.stem.2018.04.002. Epub 2018 Apr 26. Cell Stem Cell. 2018. PMID: 29706577 Free article.
2,978 results