Elsayed ZM - Search Results

1

Discovery of new sulfonamide-tethered 2-aryl-4-anilinoquinazolines as the first-in-class dual carbonic anhydrase and EGFR inhibitors.

Eldehna WM, Elsayed ZM, Ammara A, El Hassab MA, Almahli H, Fares M, Nocentini A, Supuran CT, Abou-Seri SM. Eldehna WM, et al. Among authors: elsayed zm. Int J Biol Macromol. 2024 Nov;279(Pt 2):135010. doi: 10.1016/j.ijbiomac.2024.135010. Epub 2024 Aug 26. Int J Biol Macromol. 2024. PMID: 39197616

2

Development of novel anilinoquinazoline-based carboxylic acids as non-classical carbonic anhydrase IX and XII inhibitors.

Elsayed ZM, Almahli H, Nocentini A, Ammara A, Supuran CT, Eldehna WM, Abou-Seri SM. Elsayed ZM, et al. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2191163. doi: 10.1080/14756366.2023.2191163. J Enzyme Inhib Med Chem. 2023. PMID: 36942698 Free PMC article.

3

Benzofuran-Based Carboxylic Acids as Carbonic Anhydrase Inhibitors and Antiproliferative Agents against Breast Cancer.

Eldehna WM, Nocentini A, Elsayed ZM, Al-Warhi T, Aljaeed N, Alotaibi OJ, Al-Sanea MM, Abdel-Aziz HA, Supuran CT. Eldehna WM, et al. Among authors: elsayed zm. ACS Med Chem Lett. 2020 Mar 18;11(5):1022-1027. doi: 10.1021/acsmedchemlett.0c00094. eCollection 2020 May 14. ACS Med Chem Lett. 2020. PMID: 32435420 Free PMC article.

4

3-Methylthiazolo[3,2-a]benzimidazole-benzenesulfonamide conjugates as novel carbonic anhydrase inhibitors endowed with anticancer activity: Design, synthesis, biological and molecular modeling studies.

Alkhaldi AAM, Al-Sanea MM, Nocentini A, Eldehna WM, Elsayed ZM, Bonardi A, Abo-Ashour MF, El-Damasy AK, Abdel-Maksoud MS, Al-Warhi T, Gratteri P, Abdel-Aziz HA, Supuran CT, El-Haggar R. Alkhaldi AAM, et al. Among authors: elsayed zm. Eur J Med Chem. 2020 Dec 1;207:112745. doi: 10.1016/j.ejmech.2020.112745. Epub 2020 Aug 22. Eur J Med Chem. 2020. PMID: 32877804

5

Development of novel benzofuran-based SLC-0111 analogs as selective cancer-associated carbonic anhydrase isoform IX inhibitors.

Shaldam M, Eldehna WM, Nocentini A, Elsayed ZM, Ibrahim TM, Salem R, El-Domany RA, Capasso C, Abdel-Aziz HA, Supuran CT. Shaldam M, et al. Among authors: elsayed zm. Eur J Med Chem. 2021 Apr 15;216:113283. doi: 10.1016/j.ejmech.2021.113283. Epub 2021 Feb 18. Eur J Med Chem. 2021. PMID: 33667848

6

Development of Novel Quinoline-Based Sulfonamides as Selective Cancer-Associated Carbonic Anhydrase Isoform IX Inhibitors.

Shaldam M, Nocentini A, Elsayed ZM, Ibrahim TM, Salem R, El-Domany RA, Capasso C, Supuran CT, Eldehna WM. Shaldam M, et al. Among authors: elsayed zm. Int J Mol Sci. 2021 Oct 15;22(20):11119. doi: 10.3390/ijms222011119. Int J Mol Sci. 2021. PMID: 34681794 Free PMC article.

7

Development of potent nanosized isatin-isonicotinohydrazide hybrid for management of Mycobacterium tuberculosis.

Eldehna WM, El Hassab MA, Abdelshafi NA, Al-Zahraa Sayed F, Fares M, Al-Rashood ST, Elsayed ZM, Abdel-Aziz MM, Elkaeed EB, Elsabahy M, Eissa NG. Eldehna WM, et al. Among authors: elsayed zm. Int J Pharm. 2022 Jan 25;612:121369. doi: 10.1016/j.ijpharm.2021.121369. Epub 2021 Dec 11. Int J Pharm. 2022. PMID: 34906651

8

Design, synthesis, in vitro biological assessment and molecular modeling insights for novel 3-(naphthalen-1-yl)-4,5-dihydropyrazoles as anticancer agents with potential EGFR inhibitory activity.

Eldehna WM, El Hassab MA, Elsayed ZM, Al-Warhi T, Elkady H, Abo-Ashour MF, Abourehab MAS, Eissa IH, Abdel-Aziz HA. Eldehna WM, et al. Among authors: elsayed zm. Sci Rep. 2022 Jul 27;12(1):12821. doi: 10.1038/s41598-022-15050-8. Sci Rep. 2022. PMID: 35896557 Free PMC article.

9

Development of potent nanosized carbonic anhydrase inhibitor for targeted therapy of hypoxic solid tumors.

Eldehna WM, El Hassab MA, Abdelshafi NA, Eissa RA, Diab NH, Mohamed EH, Oraby MA, Al-Rashood ST, Eissa RG, Elsayed ZM, Nocentini A, Supuran CT, Elsabahy M, Eissa NG. Eldehna WM, et al. Among authors: elsayed zm. Int J Pharm. 2023 Jan 25;631:122537. doi: 10.1016/j.ijpharm.2022.122537. Epub 2022 Dec 23. Int J Pharm. 2023. PMID: 36572260

10

1-Benzyl-5-bromo-3-hydrazonoindolin-2-ones as Novel Anticancer Agents: Synthesis, Biological Evaluation and Molecular Modeling Insights.

Al-Warhi T, Almahli H, Maklad RM, Elsayed ZM, El Hassab MA, Alotaibi OJ, Aljaeed N, Ayyad RR, Ghabour HA, Eldehna WM, El-Ashrey MK. Al-Warhi T, et al. Among authors: elsayed zm. Molecules. 2023 Apr 4;28(7):3203. doi: 10.3390/molecules28073203. Molecules. 2023. PMID: 37049966 Free PMC article.

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