Qiu C - Search Results

1

Structural basis of transcription: RNA polymerase II substrate binding and metal coordination using a free-electron laser.

Lin G, Barnes CO, Weiss S, Dutagaci B, Qiu C, Feig M, Song J, Lyubimov A, Cohen AE, Kaplan CD, Calero G. Lin G, et al. Among authors: qiu c. Proc Natl Acad Sci U S A. 2024 Sep 3;121(36):e2318527121. doi: 10.1073/pnas.2318527121. Epub 2024 Aug 27. Proc Natl Acad Sci U S A. 2024. PMID: 39190355

2

From structure to systems: high-resolution, quantitative genetic analysis of RNA polymerase II.

Braberg H, Jin H, Moehle EA, Chan YA, Wang S, Shales M, Benschop JJ, Morris JH, Qiu C, Hu F, Tang LK, Fraser JS, Holstege FC, Hieter P, Guthrie C, Kaplan CD, Krogan NJ. Braberg H, et al. Among authors: qiu c. Cell. 2013 Aug 15;154(4):775-88. doi: 10.1016/j.cell.2013.07.033. Epub 2013 Aug 8. Cell. 2013. PMID: 23932120 Free PMC article.

3

High-Resolution Phenotypic Landscape of the RNA Polymerase II Trigger Loop.

Qiu C, Erinne OC, Dave JM, Cui P, Jin H, Muthukrishnan N, Tang LK, Babu SG, Lam KC, Vandeventer PJ, Strohner R, Van den Brulle J, Sze SH, Kaplan CD. Qiu C, et al. PLoS Genet. 2016 Nov 29;12(11):e1006321. doi: 10.1371/journal.pgen.1006321. eCollection 2016 Nov. PLoS Genet. 2016. PMID: 27898685 Free PMC article.

4

Wide-ranging and unexpected consequences of altered Pol II catalytic activity in vivo.

Malik I, Qiu C, Snavely T, Kaplan CD. Malik I, et al. Among authors: qiu c. Nucleic Acids Res. 2017 May 5;45(8):4431-4451. doi: 10.1093/nar/gkx037. Nucleic Acids Res. 2017. PMID: 28119420 Free PMC article.

5

Functional assays for transcription mechanisms in high-throughput.

Qiu C, Kaplan CD. Qiu C, et al. Methods. 2019 Apr 15;159-160:115-123. doi: 10.1016/j.ymeth.2019.02.017. Epub 2019 Feb 20. Methods. 2019. PMID: 30797033 Free PMC article. Review.

6

Universal promoter scanning by Pol II during transcription initiation in Saccharomyces cerevisiae.

Qiu C, Jin H, Vvedenskaya I, Llenas JA, Zhao T, Malik I, Visbisky AM, Schwartz SL, Cui P, Čabart P, Han KH, Lai WKM, Metz RP, Johnson CD, Sze SH, Pugh BF, Nickels BE, Kaplan CD. Qiu C, et al. Genome Biol. 2020 Jun 2;21(1):132. doi: 10.1186/s13059-020-02040-0. Genome Biol. 2020. PMID: 32487207 Free PMC article.

7

A genome-wide copper-sensitized screen identifies novel regulators of mitochondrial cytochrome c oxidase activity.

Garza NM, Griffin AT, Zulkifli M, Qiu C, Kaplan CD, Gohil VM. Garza NM, et al. Among authors: qiu c. J Biol Chem. 2021 Jan-Jun;296:100485. doi: 10.1016/j.jbc.2021.100485. Epub 2021 Mar 1. J Biol Chem. 2021. PMID: 33662401 Free PMC article.

8

Widespread epistasis shapes RNA Polymerase II active site function and evolution.

Duan B, Qiu C, Sze SH, Kaplan C. Duan B, et al. Among authors: qiu c. bioRxiv [Preprint]. 2023 Apr 4:2023.02.27.530048. doi: 10.1101/2023.02.27.530048. bioRxiv. 2023. PMID: 36909581 Free PMC article. Preprint.

9

Characterization of RNA polymerase II trigger loop mutations using molecular dynamics simulations and machine learning.

Dutagaci B, Duan B, Qiu C, Kaplan CD, Feig M. Dutagaci B, et al. Among authors: qiu c. PLoS Comput Biol. 2023 Mar 22;19(3):e1010999. doi: 10.1371/journal.pcbi.1010999. eCollection 2023 Mar. PLoS Comput Biol. 2023. PMID: 36947548 Free PMC article.

10

Structural basis of transcription: RNA Polymerase II substrate binding and metal coordination at 3.0 Å using a free-electron laser.

Lin G, Barnes CO, Weiss S, Dutagaci B, Qiu C, Feig M, Song J, Lyubimov A, Cohen AE, Kaplan CD, Calero G. Lin G, et al. Among authors: qiu c. bioRxiv [Preprint]. 2023 Sep 22:2023.09.22.559052. doi: 10.1101/2023.09.22.559052. bioRxiv. 2023. Update in: Proc Natl Acad Sci U S A. 2024 Sep 3;121(36):e2318527121. doi: 10.1073/pnas.2318527121 PMID: 37790421 Free PMC article. Updated. Preprint.

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