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Page 1
Integration of genomic and pharmacokinetic data to predict clinical outcomes in HIV-associated cryptococcal meningitis.
Stott KE, Mohabir JT, Bowers K, Tenor JL, Toffaletti DL, Unsworth J, Jimenez-Valverde A, Ahmadu A, Moyo M, Gondwe E, Chimang'anga W, Chasweka M, Lawrence DS, Jarvis JN, Harrison T, Hope W, Lalloo DG, Mwandumba HC, Perfect JR, Cuomo CA; AMBITION Study Group. Stott KE, et al. Among authors: gondwe e. mBio. 2024 Oct 16;15(10):e0159224. doi: 10.1128/mbio.01592-24. Epub 2024 Aug 27. mBio. 2024. PMID: 39189739 Free PMC article.
Population pharmacokinetics and CSF penetration of flucytosine in adults with HIV-associated cryptococcal meningoencephalitis.
Stott KE, Ahmadu A, Kajanga C, Moyo M, Gondwe E, Chimang'anga W, Chasweka M, Unsworth J, Jimenez-Valverde A, Jagota B, Shah RV, Lawrence DS, Lalloo DG, Harrison T, Jarvis JN, Hope W, Mwandumba HC. Stott KE, et al. Among authors: gondwe e. J Antimicrob Chemother. 2023 Apr 3;78(4):1015-1022. doi: 10.1093/jac/dkad038. J Antimicrob Chemother. 2023. PMID: 36857467 Free PMC article.
Single-Dose Liposomal Amphotericin B Treatment for Cryptococcal Meningitis.
Jarvis JN, Lawrence DS, Meya DB, Kagimu E, Kasibante J, Mpoza E, Rutakingirwa MK, Ssebambulidde K, Tugume L, Rhein J, Boulware DR, Mwandumba HC, Moyo M, Mzinganjira H, Kanyama C, Hosseinipour MC, Chawinga C, Meintjes G, Schutz C, Comins K, Singh A, Muzoora C, Jjunju S, Nuwagira E, Mosepele M, Leeme T, Siamisang K, Ndhlovu CE, Hlupeni A, Mutata C, van Widenfelt E, Chen T, Wang D, Hope W, Boyer-Chammard T, Loyse A, Molloy SF, Youssouf N, Lortholary O, Lalloo DG, Jaffar S, Harrison TS; Ambition Study Group. Jarvis JN, et al. N Engl J Med. 2022 Mar 24;386(12):1109-1120. doi: 10.1056/NEJMoa2111904. N Engl J Med. 2022. PMID: 35320642 Free PMC article. Clinical Trial.
Cost-effectiveness of single, high-dose, liposomal amphotericin regimen for HIV-associated cryptococcal meningitis in five countries in sub-Saharan Africa: an economic analysis of the AMBITION-cm trial.
Lawrence DS, Muthoga C, Meya DB, Tugume L, Williams D, Rajasingham R, Boulware DR, Mwandumba HC, Moyo M, Dziwani EN, Maheswaran H, Kanyama C, Hosseinipour MC, Chawinga C, Meintjes G, Schutz C, Comins K, Bango F, Muzoora C, Jjunju S, Nuwagira E, Mosepele M, Leeme T, Ndhlovu CE, Hlupeni A, Shamu S, Boyer-Chammard T, Molloy SF, Youssouf N, Chen T, Shiri T, Jaffar S, Harrison TS, Jarvis JN, Niessen LW; AMBITION Study Group. Lawrence DS, et al. Lancet Glob Health. 2022 Dec;10(12):e1845-e1854. doi: 10.1016/S2214-109X(22)00450-8. Lancet Glob Health. 2022. PMID: 36400090 Free PMC article.
Population pharmacokinetics of liposomal amphotericin B in adults with HIV-associated cryptococcal meningoencephalitis.
Stott KE, Moyo M, Ahmadu A, Kajanga C, Gondwe E, Chimang'anga W, Chasweka M, Leeme TB, Molefi M, Chofle A, Bidwell G, Changalucha J, Unsworth J, Jimenez-Valverde A, Lawrence DS, Mwandumba HC, Lalloo DG, Harrison TS, Jarvis JN, Hope W, Märtson AG. Stott KE, et al. Among authors: gondwe e. J Antimicrob Chemother. 2022 Dec 23;78(1):276-283. doi: 10.1093/jac/dkac389. J Antimicrob Chemother. 2022. PMID: 36411251 Free PMC article.
Development and validation of quantitative PCR assays for HIV-associated cryptococcal meningitis in sub-Saharan Africa: a diagnostic accuracy study.
Mbangiwa T, Sturny-Leclère A, Lechiile K, Kajanga C, Boyer-Chammard T, Hoving JC, Leeme T, Moyo M, Youssouf N, Lawrence DS, Mwandumba H, Mosepele M, Harrison TS, Jarvis JN, Lortholary O, Alanio A; AMBITION Study Group. Mbangiwa T, et al. Lancet Microbe. 2024 Mar;5(3):e261-e271. doi: 10.1016/S2666-5247(23)00362-2. Epub 2024 Feb 8. Lancet Microbe. 2024. PMID: 38342110 Free PMC article.
AMBIsome Therapy Induction OptimisatioN (AMBITION): High dose AmBisome for cryptococcal meningitis induction therapy in sub-Saharan Africa: economic evaluation protocol for a randomised controlled trial-based equivalence study.
Ponatshego PL, Lawrence DS, Youssouf N, Molloy SF, Alufandika M, Bango F, Boulware DR, Chawinga C, Dziwani E, Gondwe E, Hlupeni A, Hosseinipour MC, Kanyama C, Meya DB, Mosepele M, Muthoga C, Muzoora CK, Mwandumba H, Ndhlovu CE, Rajasingham R, Sayed S, Shamu S, Tsholo K, Tugume L, Williams D, Maheswaran H, Shiri T, Boyer-Chammard T, Loyse A, Chen T, Wang D, Lortholary O, Lalloo DG, Meintjes G, Jaffar S, Harrison TS, Jarvis JN, Niessen LW. Ponatshego PL, et al. Among authors: gondwe e. BMJ Open. 2019 Apr 1;9(4):e026288. doi: 10.1136/bmjopen-2018-026288. BMJ Open. 2019. PMID: 30940760 Free PMC article. Clinical Trial.
Antifungal Combinations for Treatment of Cryptococcal Meningitis in Africa.
Molloy SF, Kanyama C, Heyderman RS, Loyse A, Kouanfack C, Chanda D, Mfinanga S, Temfack E, Lakhi S, Lesikari S, Chan AK, Stone N, Kalata N, Karunaharan N, Gaskell K, Peirse M, Ellis J, Chawinga C, Lontsi S, Ndong JG, Bright P, Lupiya D, Chen T, Bradley J, Adams J, van der Horst C, van Oosterhout JJ, Sini V, Mapoure YN, Mwaba P, Bicanic T, Lalloo DG, Wang D, Hosseinipour MC, Lortholary O, Jaffar S, Harrison TS; ACTA Trial Study Team. Molloy SF, et al. N Engl J Med. 2018 Mar 15;378(11):1004-1017. doi: 10.1056/NEJMoa1710922. N Engl J Med. 2018. PMID: 29539274 Free article. Clinical Trial.
Spatial analysis of aquatic food access can inform nutrition-sensitive policy.
Bennett A, Rice E, Muhonda P, Kaunda E, Katengeza S, Liverpool-Tasie LSO, Belton B, Infante DM, Ross J, Virdin J, Gondwe E. Bennett A, et al. Among authors: gondwe e. Nat Food. 2022 Dec;3(12):1010-1013. doi: 10.1038/s43016-022-00642-4. Epub 2022 Dec 15. Nat Food. 2022. PMID: 37118314
30 results