Park CY - Search Results

1

Decomposition of phenotypic heterogeneity in autism reveals distinct and coherent genetic programs.

Litman A, Sauerwald N, Snyder LG, Foss-Feig J, Park CY, Hao Y, Dinstein I, Theesfeld CL, Troyanskaya OG. Litman A, et al. Among authors: park cy. medRxiv [Preprint]. 2024 Aug 16:2024.08.15.24312078. doi: 10.1101/2024.08.15.24312078. medRxiv. 2024. PMID: 39185525 Free PMC article. Preprint.

2

Genome-wide landscape of RNA-binding protein target site dysregulation reveals a major impact on psychiatric disorder risk.

Park CY, Zhou J, Wong AK, Chen KM, Theesfeld CL, Darnell RB, Troyanskaya OG. Park CY, et al. Nat Genet. 2021 Feb;53(2):166-173. doi: 10.1038/s41588-020-00761-3. Epub 2021 Jan 18. Nat Genet. 2021. PMID: 33462483 Free PMC article.

3

Tissue-specific enhancer functional networks for associating distal regulatory regions to disease.

Chen X, Zhou J, Zhang R, Wong AK, Park CY, Theesfeld CL, Troyanskaya OG. Chen X, et al. Among authors: park cy. Cell Syst. 2021 Apr 21;12(4):353-362.e6. doi: 10.1016/j.cels.2021.02.002. Epub 2021 Mar 8. Cell Syst. 2021. PMID: 33689683 Free article.

4

Whole-genome deep-learning analysis identifies contribution of noncoding mutations to autism risk.

Zhou J, Park CY, Theesfeld CL, Wong AK, Yuan Y, Scheckel C, Fak JJ, Funk J, Yao K, Tajima Y, Packer A, Darnell RB, Troyanskaya OG. Zhou J, et al. Among authors: park cy. Nat Genet. 2019 Jun;51(6):973-980. doi: 10.1038/s41588-019-0420-0. Epub 2019 May 27. Nat Genet. 2019. PMID: 31133750 Free PMC article.

5

Specific viral RNA drives the SARS CoV-2 nucleocapsid to phase separate.

Iserman C, Roden C, Boerneke M, Sealfon R, McLaughlin G, Jungreis I, Park C, Boppana A, Fritch E, Hou YJ, Theesfeld C, Troyanskaya OG, Baric RS, Sheahan TP, Weeks K, Gladfelter AS. Iserman C, et al. bioRxiv [Preprint]. 2020 Jun 12:2020.06.11.147199. doi: 10.1101/2020.06.11.147199. bioRxiv. 2020. PMID: 32587965 Free PMC article. Preprint.

6

Simultaneous genome-wide inference of physical, genetic, regulatory, and functional pathway components.

Park CY, Hess DC, Huttenhower C, Troyanskaya OG. Park CY, et al. PLoS Comput Biol. 2010 Nov 24;6(11):e1001009. doi: 10.1371/journal.pcbi.1001009. PLoS Comput Biol. 2010. PMID: 21124865 Free PMC article.

7

Tissue-aware data integration approach for the inference of pathway interactions in metazoan organisms.

Park CY, Krishnan A, Zhu Q, Wong AK, Lee YS, Troyanskaya OG. Park CY, et al. Bioinformatics. 2015 Apr 1;31(7):1093-101. doi: 10.1093/bioinformatics/btu786. Epub 2014 Nov 26. Bioinformatics. 2015. PMID: 25431329 Free PMC article.

8

IMP: a multi-species functional genomics portal for integration, visualization and prediction of protein functions and networks.

Wong AK, Park CY, Greene CS, Bongo LA, Guan Y, Troyanskaya OG. Wong AK, et al. Among authors: park cy. Nucleic Acids Res. 2012 Jul;40(Web Server issue):W484-90. doi: 10.1093/nar/gks458. Epub 2012 Jun 7. Nucleic Acids Res. 2012. PMID: 22684505 Free PMC article.

9

Functional knowledge transfer for high-accuracy prediction of under-studied biological processes.

Park CY, Wong AK, Greene CS, Rowland J, Guan Y, Bongo LA, Burdine RD, Troyanskaya OG. Park CY, et al. PLoS Comput Biol. 2013;9(3):e1002957. doi: 10.1371/journal.pcbi.1002957. Epub 2013 Mar 14. PLoS Comput Biol. 2013. PMID: 23516347 Free PMC article.

10

Interactive Big Data Resource to Elucidate Human Immune Pathways and Diseases.

Gorenshteyn D, Zaslavsky E, Fribourg M, Park CY, Wong AK, Tadych A, Hartmann BM, Albrecht RA, García-Sastre A, Kleinstein SH, Troyanskaya OG, Sealfon SC. Gorenshteyn D, et al. Among authors: park cy. Immunity. 2015 Sep 15;43(3):605-14. doi: 10.1016/j.immuni.2015.08.014. Epub 2015 Sep 8. Immunity. 2015. PMID: 26362267 Free PMC article.

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