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Glial reactivity is linked to synaptic dysfunction across the aging and Alzheimer's disease spectrum.
Pascoal T, Rohden F, Ferreira P, Bellaver B, Ferrari-Souza JP, Aguzzoli C, Soares C, Abbas S, Zalzale H, Povala G, Lussier F, Leffa D, Bauer-Negrini G, Rahmouni N, Tissot C, Therriault JT, Servaes S, Stevenson J, Benedet A, Ashton N, Karikari T, Tudorascu D, Zetterberg H, Blennow K, Zimmer E, Souza D, Rosa-Neto P. Pascoal T, et al. Res Sq [Preprint]. 2024 Aug 12:rs.3.rs-4782732. doi: 10.21203/rs.3.rs-4782732/v1. Res Sq. 2024. PMID: 39184102 Free PMC article. Preprint.
Association Between β-Amyloid Accumulation and Incident Dementia in Individuals 80 Years or Older Without Dementia.
Lopez OL, Villemagne VL, Chang YF, Cohen AD, Klunk WE, Mathis CA, Pascoal T, Ikonomovic MD, Rowe C, Dore V, Snitz BE, Lopresti BJ, Kamboh MI, Aizenstein HJ, Kuller LH. Lopez OL, et al. Among authors: pascoal t. Neurology. 2024 Jan 23;102(2):e207920. doi: 10.1212/WNL.0000000000207920. Epub 2023 Dec 22. Neurology. 2024. PMID: 38165336 Free PMC article.
Epistasis analysis links immune cascades and cerebral amyloidosis.
Benedet AL, Labbe A, Lemay P, Zimmer ER, Pascoal TA, Leuzy A, Mathotaarachchi S, Mohades S, Shin M, Dionne-Laporte A, Beaudry T, Picard C, Gauthier S, Poirier J, Rouleau G, Rosa-Neto P; Alzheimer’s Disease Neuroimaging Initiative. Benedet AL, et al. Among authors: pascoal ta. J Neuroinflammation. 2015 Dec 1;12:227. doi: 10.1186/s12974-015-0436-z. J Neuroinflammation. 2015. PMID: 26626881 Free PMC article.
Neuropsychiatric symptoms predict hypometabolism in preclinical Alzheimer disease.
Ng KP, Pascoal TA, Mathotaarachchi S, Chung CO, Benedet AL, Shin M, Kang MS, Li X, Ba M, Kandiah N, Rosa-Neto P, Gauthier S; Alzheimer's Disease Neuroimaging Initiative. Ng KP, et al. Neurology. 2017 May 9;88(19):1814-1821. doi: 10.1212/WNL.0000000000003916. Epub 2017 Apr 12. Neurology. 2017. PMID: 28404803 Free PMC article.
Identifying incipient dementia individuals using machine learning and amyloid imaging.
Mathotaarachchi S, Pascoal TA, Shin M, Benedet AL, Kang MS, Beaudry T, Fonov VS, Gauthier S, Rosa-Neto P; Alzheimer's Disease Neuroimaging Initiative. Mathotaarachchi S, et al. Among authors: pascoal ta. Neurobiol Aging. 2017 Nov;59:80-90. doi: 10.1016/j.neurobiolaging.2017.06.027. Epub 2017 Jul 11. Neurobiol Aging. 2017. PMID: 28756942 Free article.
Imaging Alzheimer's disease pathophysiology with PET.
Schilling LP, Zimmer ER, Shin M, Leuzy A, Pascoal TA, Benedet AL, Borelli WV, Palmini A, Gauthier S, Rosa-Neto P. Schilling LP, et al. Dement Neuropsychol. 2016 Apr-Jun;10(2):79-90. doi: 10.1590/S1980-5764-2016DN1002003. Dement Neuropsychol. 2016. PMID: 29213438 Free PMC article. Review.
Amyloid and tau signatures of brain metabolic decline in preclinical Alzheimer's disease.
Pascoal TA, Mathotaarachchi S, Shin M, Park AY, Mohades S, Benedet AL, Kang MS, Massarweh G, Soucy JP, Gauthier S, Rosa-Neto P; Alzheimer’s Disease Neuroimaging Initiative. Pascoal TA, et al. Eur J Nucl Med Mol Imaging. 2018 Jun;45(6):1021-1030. doi: 10.1007/s00259-018-3933-3. Epub 2018 Feb 2. Eur J Nucl Med Mol Imaging. 2018. PMID: 29396637 Free PMC article.
CYP2C19 variant mitigates Alzheimer disease pathophysiology in vivo and postmortem.
Benedet AL, Yu L, Labbe A, Mathotaarachchi S, Pascoal TA, Shin M, Kang MS, Gauthier S, Rouleau GA, Poirier J, Bennett DA, Rosa-Neto P; Alzheimer's Disease Neuroimaging Initiative. Benedet AL, et al. Neurol Genet. 2018 Jan 30;4(1):e216. doi: 10.1212/NXG.0000000000000216. eCollection 2018 Feb. Neurol Genet. 2018. PMID: 29473050 Free PMC article.
185 results