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Page 1
The systemic complexity of a monogenic disease: the molecular network of spinal muscular atrophy.
Tapken I, Schweitzer T, Paganin M, Schüning T, Detering NT, Sharma G, Niesert M, Saffari A, Kuhn D, Glynn A, Cieri F, Santonicola P, Cannet C, Gerstner F, Faller KME, Huang YT, Kothary R, Gillingwater TH, Di Schiavi E, Simon CM, Hensel N, Ziegler A, Viero G, Pich A, Claus P. Tapken I, et al. Among authors: paganin m. Brain. 2024 Aug 26:awae272. doi: 10.1093/brain/awae272. Online ahead of print. Brain. 2024. PMID: 39183150
CircFBXW7 in patients with T-cell ALL: depletion sustains MYC and NOTCH activation and leukemia cell viability.
Buratin A, Borin C, Tretti Parenzan C, Dal Molin A, Orsi S, Binatti A, Simon K, Paganin M, Serafin V, Gaffo E, Te Kronnie G, Van Vlierberghe P, Bresolin S, Bortoluzzi S. Buratin A, et al. Among authors: paganin m. Exp Hematol Oncol. 2023 Jan 21;12(1):12. doi: 10.1186/s40164-023-00374-6. Exp Hematol Oncol. 2023. PMID: 36681829 Free PMC article.
Either IL-7 activation of JAK-STAT or BEZ inhibition of PI3K-AKT-mTOR pathways dominates the single-cell phosphosignature of ex vivo treated pediatric T-cell acute lymphoblastic leukemia cells.
Kuzilková D, Bugarin C, Rejlova K, Schulz AR, Mei HE, Paganin M, Biffi A, Biondi A, Kalina T, Gaipa G. Kuzilková D, et al. Among authors: paganin m. Haematologica. 2022 Jun 1;107(6):1293-1310. doi: 10.3324/haematol.2021.278796. Haematologica. 2022. PMID: 34670357 Free PMC article.
Mutational and functional genetics mapping of chemotherapy resistance mechanisms in relapsed acute lymphoblastic leukemia.
Oshima K, Zhao J, Pérez-Durán P, Brown JA, Patiño-Galindo JA, Chu T, Quinn A, Gunning T, Belver L, Ambesi-Impiombato A, Tosello V, Wang Z, Sulis ML, Kato M, Koh K, Paganin M, Basso G, Balbin M, Nicolas C, Gastier-Foster JM, Devidas M, Loh ML, Paietta E, Tallman MS, Rowe JM, Litzow M, Minden MD, Meijerink J, Rabadan R, Ferrando A. Oshima K, et al. Among authors: paganin m. Nat Cancer. 2020 Nov;1(11):1113-1127. doi: 10.1038/s43018-020-00124-1. Epub 2020 Oct 19. Nat Cancer. 2020. PMID: 33796864 Free PMC article.
Large-scale circular RNA deregulation in T-ALL: unlocking unique ectopic expression of molecular subtypes.
Buratin A, Paganin M, Gaffo E, Dal Molin A, Roels J, Germano G, Siddi MT, Serafin V, De Decker M, Gachet S, Durinck K, Speleman F, Taghon T, Te Kronnie G, Van Vlierberghe P, Bortoluzzi S. Buratin A, et al. Among authors: paganin m. Blood Adv. 2020 Dec 8;4(23):5902-5914. doi: 10.1182/bloodadvances.2020002337. Blood Adv. 2020. PMID: 33259601 Free PMC article.
Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia.
Zhou Y, Han C, Wang E, Lorch AH, Serafin V, Cho BK, Gutierrez Diaz BT, Calvo J, Fang C, Khodadadi-Jamayran A, Tabaglio T, Marier C, Kuchmiy A, Sun L, Yacu G, Filip SK, Jin Q, Takahashi YH, Amici DR, Rendleman EJ, Rawat R, Bresolin S, Paganin M, Zhang C, Li H, Kandela I, Politanska Y, Abdala-Valencia H, Mendillo ML, Zhu P, Palhais B, Van Vlierberghe P, Taghon T, Aifantis I, Goo YA, Guccione E, Heguy A, Tsirigos A, Wee KB, Mishra RK, Pflumio F, Accordi B, Basso G, Ntziachristos P. Zhou Y, et al. Among authors: paganin m. Cancer Discov. 2020 Sep;10(9):1388-1409. doi: 10.1158/2159-8290.CD-19-1436. Epub 2020 May 22. Cancer Discov. 2020. PMID: 32444465 Free PMC article.
Phf6 Loss Enhances HSC Self-Renewal Driving Tumor Initiation and Leukemia Stem Cell Activity in T-ALL.
Wendorff AA, Quinn SA, Rashkovan M, Madubata CJ, Ambesi-Impiombato A, Litzow MR, Tallman MS, Paietta E, Paganin M, Basso G, Gastier-Foster JM, Loh ML, Rabadan R, Van Vlierberghe P, Ferrando AA. Wendorff AA, et al. Among authors: paganin m. Cancer Discov. 2019 Mar;9(3):436-451. doi: 10.1158/2159-8290.CD-18-1005. Epub 2018 Dec 19. Cancer Discov. 2019. PMID: 30567843 Free PMC article.
32 results