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Page 1
RSV and rhinovirus increase pneumococcal carriage acquisition and density, whereas nasal inflammation is associated with bacterial shedding.
Mitsi E, Nikolaou E, Goncalves A, Blizard A, Hill H, Farrar M, Hyder-Wright A, Akeju O, Hamilton J, Howard A, Elterish F, Solorzano C, Robinson R, Reiné J, Collins AM, Gordon SB, Moxon RE, Weiser JN, Bogaert D, Ferreira DM. Mitsi E, et al. Among authors: nikolaou e. Cell Host Microbe. 2024 Sep 11;32(9):1608-1620.e4. doi: 10.1016/j.chom.2024.07.024. Epub 2024 Aug 23. Cell Host Microbe. 2024. PMID: 39181126
Polysaccharide-Specific Memory B Cells Predict Protection against Experimental Human Pneumococcal Carriage.
Pennington SH, Pojar S, Mitsi E, Gritzfeld JF, Nikolaou E, Solórzano C, Owugha JT, Masood Q, Gordon MA, Wright AD, Collins AM, Miyaji EN, Gordon SB, Ferreira DM. Pennington SH, et al. Among authors: nikolaou e. Am J Respir Crit Care Med. 2016 Dec 15;194(12):1523-1531. doi: 10.1164/rccm.201512-2467OC. Am J Respir Crit Care Med. 2016. PMID: 27403678 Free PMC article.
Inflammation induced by influenza virus impairs human innate immune control of pneumococcus.
Jochems SP, Marcon F, Carniel BF, Holloway M, Mitsi E, Smith E, Gritzfeld JF, Solórzano C, Reiné J, Pojar S, Nikolaou E, German EL, Hyder-Wright A, Hill H, Hales C, de Steenhuijsen Piters WAA, Bogaert D, Adler H, Zaidi S, Connor V, Gordon SB, Rylance J, Nakaya HI, Ferreira DM. Jochems SP, et al. Among authors: nikolaou e. Nat Immunol. 2018 Dec;19(12):1299-1308. doi: 10.1038/s41590-018-0231-y. Epub 2018 Oct 29. Nat Immunol. 2018. PMID: 30374129 Free PMC article. Clinical Trial.
Pneumococcal Colonization in Healthy Adult Research Participants in the Conjugate Vaccine Era, United Kingdom, 2010-2017.
Adler H, Nikolaou E, Gould K, Hinds J, Collins AM, Connor V, Hales C, Hill H, Hyder-Wright AD, Zaidi SR, German EL, Gritzfeld JF, Mitsi E, Pojar S, Gordon SB, Roberts AP, Rylance J, Ferreira DM. Adler H, et al. Among authors: nikolaou e. J Infect Dis. 2019 May 24;219(12):1989-1993. doi: 10.1093/infdis/jiz034. J Infect Dis. 2019. PMID: 30690468 Free PMC article.
Innate and adaptive nasal mucosal immune responses following experimental human pneumococcal colonization.
Jochems SP, de Ruiter K, Solórzano C, Voskamp A, Mitsi E, Nikolaou E, Carniel BF, Pojar S, German EL, Reiné J, Soares-Schanoski A, Hill H, Robinson R, Hyder-Wright AD, Weight CM, Durrenberger PF, Heyderman RS, Gordon SB, Smits HH, Urban BC, Rylance J, Collins AM, Wilkie MD, Lazarova L, Leong SC, Yazdanbakhsh M, Ferreira DM. Jochems SP, et al. Among authors: nikolaou e. J Clin Invest. 2019 Jul 30;129(10):4523-4538. doi: 10.1172/JCI128865. J Clin Invest. 2019. PMID: 31361601 Free PMC article. Clinical Trial.
Nasal Pneumococcal Density Is Associated with Microaspiration and Heightened Human Alveolar Macrophage Responsiveness to Bacterial Pathogens.
Mitsi E, Carniel B, Reiné J, Rylance J, Zaidi S, Soares-Schanoski A, Connor V, Collins AM, Schlitzer A, Nikolaou E, Solórzano C, Pojar S, Hill H, Hyder-Wright AD, Jambo KC, Oggioni MR, De Ste Croix M, Gordon SB, Jochems SP, Ferreira DM. Mitsi E, et al. Among authors: nikolaou e. Am J Respir Crit Care Med. 2020 Feb 1;201(3):335-347. doi: 10.1164/rccm.201903-0607OC. Am J Respir Crit Care Med. 2020. PMID: 31626559 Free PMC article.
Symptoms associated with influenza vaccination and experimental human pneumococcal colonisation of the nasopharynx.
Hales C, Jochems SP, Robinson R, Solórzano C, Carniel B, Pojar S, Reiné J, German EL, Nikolaou E, Mitsi E, Hyder-Wright AD, Hill H, Adler H, Connor V, Zaidi S, Lowe C, Fan X, Wang D, Gordon SB, Rylance J, Ferreira DM. Hales C, et al. Among authors: nikolaou e. Vaccine. 2020 Feb 28;38(10):2298-2306. doi: 10.1016/j.vaccine.2020.01.070. Epub 2020 Feb 5. Vaccine. 2020. PMID: 32035708 Free PMC article. Clinical Trial.
Experimental Human Pneumococcal Colonization in Older Adults Is Feasible and Safe, Not Immunogenic.
Adler H, German EL, Mitsi E, Nikolaou E, Pojar S, Hales C, Robinson R, Connor V, Hill H, Hyder-Wright AD, Lazarova L, Lowe C, Smith EL, Wheeler I, Zaidi SR, Jochems SP, Loukov D, Reiné J, Solórzano-Gonzalez C, de Gorguette d'Argoeuves P, Jones T, Goldblatt D, Chen T, Aston SJ, French N, Collins AM, Gordon SB, Ferreira DM, Rylance J. Adler H, et al. Among authors: nikolaou e. Am J Respir Crit Care Med. 2021 Mar 1;203(5):604-613. doi: 10.1164/rccm.202004-1483OC. Am J Respir Crit Care Med. 2021. PMID: 32941735 Free PMC article.
Experimental Human Challenge Defines Distinct Pneumococcal Kinetic Profiles and Mucosal Responses between Colonized and Non-Colonized Adults.
Nikolaou E, Jochems SP, Mitsi E, Pojar S, Blizard A, Reiné J, Solórzano C, Negera E, Carniel B, Soares-Schanoski A, Connor V, Adler H, Zaidi SR, Hales C, Hill H, Hyder-Wright A, Gordon SB, Rylance J, Ferreira DM. Nikolaou E, et al. mBio. 2021 Jan 12;12(1):e02020-20. doi: 10.1128/mBio.02020-20. mBio. 2021. PMID: 33436429 Free PMC article.
82 results