Dehertogh P - Search Results

1

Robust isolation protocol for mouse leukocytes from blood and liver resident cells for immunology research.

De Pooter D, De Clerck B, Dockx K, De Santis D, Sauviller S, Dehertogh P, Beyens M, Bergiers I, Nájera I, Van Gulck E, Conceição-Neto N, Pierson W. De Pooter D, et al. Among authors: dehertogh p. PLoS One. 2024 Aug 22;19(8):e0304063. doi: 10.1371/journal.pone.0304063. eCollection 2024. PLoS One. 2024. PMID: 39172771 Free PMC article.

2

Anti-HBV activity of the HBV capsid assembly modulator JNJ-56136379 across full-length genotype A-H clinical isolates and core site-directed mutants in vitro.

Verbinnen T, Tan Y, Wang G, Dehertogh P, Vergauwen K, Neefs JM, Jacoby E, Lenz O, Berke JM. Verbinnen T, et al. Among authors: dehertogh p. J Antimicrob Chemother. 2020 Sep 1;75(9):2526-2534. doi: 10.1093/jac/dkaa179. J Antimicrob Chemother. 2020. PMID: 32417895

3

Antiviral Properties and Mechanism of Action Studies of the Hepatitis B Virus Capsid Assembly Modulator JNJ-56136379.

Berke JM, Dehertogh P, Vergauwen K, Mostmans W, Vandyck K, Raboisson P, Pauwels F. Berke JM, et al. Among authors: dehertogh p. Antimicrob Agents Chemother. 2020 Apr 21;64(5):e02439-19. doi: 10.1128/AAC.02439-19. Print 2020 Apr 21. Antimicrob Agents Chemother. 2020. PMID: 32094138 Free PMC article.

4

Synthesis and Evaluation of N-Phenyl-3-sulfamoyl-benzamide Derivatives as Capsid Assembly Modulators Inhibiting Hepatitis B Virus (HBV).

Vandyck K, Rombouts G, Stoops B, Tahri A, Vos A, Verschueren W, Wu Y, Yang J, Hou F, Huang B, Vergauwen K, Dehertogh P, Berke JM, Raboisson P. Vandyck K, et al. Among authors: dehertogh p. J Med Chem. 2018 Jul 26;61(14):6247-6260. doi: 10.1021/acs.jmedchem.8b00654. Epub 2018 Jul 3. J Med Chem. 2018. PMID: 29906396

5

Antiviral profiling of the capsid assembly modulator BAY41-4109 on full-length HBV genotype A-H clinical isolates and core site-directed mutants in vitro.

Berke JM, Tan Y, Verbinnen T, Dehertogh P, Vergauwen K, Vos A, Lenz O, Pauwels F. Berke JM, et al. Among authors: dehertogh p. Antiviral Res. 2017 Aug;144:205-215. doi: 10.1016/j.antiviral.2017.06.016. Epub 2017 Jun 21. Antiviral Res. 2017. PMID: 28647474

6

Capsid Assembly Modulators Have a Dual Mechanism of Action in Primary Human Hepatocytes Infected with Hepatitis B Virus.

Berke JM, Dehertogh P, Vergauwen K, Van Damme E, Mostmans W, Vandyck K, Pauwels F. Berke JM, et al. Among authors: dehertogh p. Antimicrob Agents Chemother. 2017 Jul 25;61(8):e00560-17. doi: 10.1128/AAC.00560-17. Print 2017 Aug. Antimicrob Agents Chemother. 2017. PMID: 28584155 Free PMC article.

7

Discovery and early development of TMC647055, a non-nucleoside inhibitor of the hepatitis C virus NS5B polymerase.

Cummings MD, Lin TI, Hu L, Tahri A, McGowan D, Amssoms K, Last S, Devogelaere B, Rouan MC, Vijgen L, Berke JM, Dehertogh P, Fransen E, Cleiren E, van der Helm L, Fanning G, Nyanguile O, Simmen K, Van Remoortere P, Raboisson P, Vendeville S. Cummings MD, et al. Among authors: dehertogh p. J Med Chem. 2014 Mar 13;57(5):1880-92. doi: 10.1021/jm401396p. Epub 2013 Nov 8. J Med Chem. 2014. PMID: 24144360

8

Identification of HIV-1 reverse transcriptase inhibitors using a scintillation proximity assay.

Van Schoubroeck B, Van Loock M, Ivens T, Dehertogh P, Jochmans D, Dams G. Van Schoubroeck B, et al. Among authors: dehertogh p. Methods Mol Biol. 2013;1030:19-24. doi: 10.1007/978-1-62703-484-5_3. Methods Mol Biol. 2013. PMID: 23821257

9

TMC647055, a potent nonnucleoside hepatitis C virus NS5B polymerase inhibitor with cross-genotypic coverage.

Devogelaere B, Berke JM, Vijgen L, Dehertogh P, Fransen E, Cleiren E, van der Helm L, Nyanguile O, Tahri A, Amssoms K, Lenz O, Cummings MD, Clayton RF, Vendeville S, Raboisson P, Simmen KA, Fanning GC, Lin TI. Devogelaere B, et al. Among authors: dehertogh p. Antimicrob Agents Chemother. 2012 Sep;56(9):4676-84. doi: 10.1128/AAC.00245-12. Epub 2012 Jun 18. Antimicrob Agents Chemother. 2012. PMID: 22710121 Free PMC article.

10

Finger loop inhibitors of the HCV NS5b polymerase. Part II. Optimization of tetracyclic indole-based macrocycle leading to the discovery of TMC647055.

Vendeville S, Lin TI, Hu L, Tahri A, McGowan D, Cummings MD, Amssoms K, Canard M, Last S, Van den Steen I, Devogelaere B, Rouan MC, Vijgen L, Berke JM, Dehertogh P, Fransen E, Cleiren E, van der Helm L, Fanning G, Van Emelen K, Nyanguile O, Simmen K, Raboisson P. Vendeville S, et al. Among authors: dehertogh p. Bioorg Med Chem Lett. 2012 Jul 1;22(13):4437-43. doi: 10.1016/j.bmcl.2012.04.113. Epub 2012 Apr 30. Bioorg Med Chem Lett. 2012. PMID: 22633687

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