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Page 1
Single-cell RNA and T-cell receptor sequencing unveil mycosis fungoides heterogeneity and a possible gene signature.
Srinivas N, Peiffer L, Horny K, Lei KC, Buus TB, Kubat L, Luo M, Yin M, Spassova I, Sucker A, Farahpour F, Kehrmann J, Ugurel S, Livingstone E, Gambichler T, Ødum N, Becker JC. Srinivas N, et al. Among authors: kubat l. Front Oncol. 2024 Aug 7;14:1408614. doi: 10.3389/fonc.2024.1408614. eCollection 2024. Front Oncol. 2024. PMID: 39169943 Free PMC article.
The RANKL inhibitor denosumab in combination with dual checkpoint inhibition is associated with increased CXCL-13 serum concentrations.
Schaper-Gerhardt K, Gutzmer R, Angela Y, Zimmer L, Livingstone E, Schadendorf D, Hassel JC, Weishaupt C, Remes B, Kubat L, Spassova I, Becker JC. Schaper-Gerhardt K, et al. Among authors: kubat l. Eur J Cancer. 2024 May;202:113984. doi: 10.1016/j.ejca.2024.113984. Epub 2024 Mar 2. Eur J Cancer. 2024. PMID: 38479119 Free article.
Phenotypic plasticity of malignant T cells in blood and skin of a Sézary syndrome patient revealed by single cell transcriptomics.
Peiffer L, Gambichler T, Buus TB, Horny K, Gravemeyer J, Furtmann F, Spassova I, Kubat L, Susok L, Stranzenbach R, Srinivas N, Ødum N, Becker JC. Peiffer L, et al. Among authors: kubat l. Front Oncol. 2023 Jan 25;13:1090592. doi: 10.3389/fonc.2023.1090592. eCollection 2023. Front Oncol. 2023. PMID: 36761972 Free PMC article.
Persister state-directed transitioning and vulnerability in melanoma.
Chauvistré H, Shannan B, Daignault-Mill SM, Ju RJ, Picard D, Egetemaier S, Váraljai R, Gibhardt CS, Sechi A, Kaschani F, Keminer O, Stehbens SJ, Liu Q, Yin X, Jeyakumar K, Vogel FCE, Krepler C, Rebecca VW, Kubat L, Lueong SS, Forster J, Horn S, Remke M, Ehrmann M, Paschen A, Becker JC, Helfrich I, Rauh D, Kaiser M, Gul S, Herlyn M, Bogeski I, Rodríguez-López JN, Haass NK, Schadendorf D, Roesch A. Chauvistré H, et al. Among authors: kubat l. Nat Commun. 2022 Jun 1;13(1):3055. doi: 10.1038/s41467-022-30641-9. Nat Commun. 2022. PMID: 35650266 Free PMC article.
Clinical and molecular characteristics associated with response to therapeutic PD-1/PD-L1 inhibition in advanced Merkel cell carcinoma.
Spassova I, Ugurel S, Kubat L, Zimmer L, Terheyden P, Mohr A, Björn Andtback H, Villabona L, Leiter U, Eigentler T, Loquai C, Hassel JC, Gambichler T, Haferkamp S, Mohr P, Pfoehler C, Heinzerling L, Gutzmer R, Utikal JS, Horny K, Schildhaus HU, Habermann D, Hoffmann D, Schadendorf D, Becker JC. Spassova I, et al. Among authors: kubat l. J Immunother Cancer. 2022 Jan;10(1):e003198. doi: 10.1136/jitc-2021-003198. J Immunother Cancer. 2022. PMID: 35074902 Free PMC article.
UV-type specific alteration of miRNA expression and its association with tumor progression and metastasis in SCC cell lines.
Chen IP, Bender M, Spassova I, Henning S, Kubat L, Fan K, Degenhardt S, Mhamdi-Ghodbani M, Sriram A, Volkmer B, Boukamp P, Becker JC, Greinert R. Chen IP, et al. Among authors: kubat l. J Cancer Res Clin Oncol. 2020 Dec;146(12):3215-3231. doi: 10.1007/s00432-020-03358-9. Epub 2020 Aug 31. J Cancer Res Clin Oncol. 2020. PMID: 32865618
T-Cell Repertoire in Combination with T-Cell Density Predicts Clinical Outcomes in Patients with Merkel Cell Carcinoma.
Farah M, Reuben A, Spassova I, Yang RK, Kubat L, Nagarajan P, Ning J, Li W, Aung PP, Curry JL, Torres-Cabala CA, Hudgens CW, Ugurel S, Schadendorf D, Gumbs C, Little LD, Futreal A, Wistuba II, Prieto VG, Wang L, Wong MK, Wargo JA, Becker JC, Tetzlaff MT. Farah M, et al. Among authors: kubat l. J Invest Dermatol. 2020 Nov;140(11):2146-2156.e4. doi: 10.1016/j.jid.2020.02.031. Epub 2020 Apr 15. J Invest Dermatol. 2020. PMID: 32304704 Free article.
Predominance of Central Memory T Cells with High T-Cell Receptor Repertoire Diversity is Associated with Response to PD-1/PD-L1 Inhibition in Merkel Cell Carcinoma.
Spassova I, Ugurel S, Terheyden P, Sucker A, Hassel JC, Ritter C, Kubat L, Habermann D, Farahpour F, Saeedghalati M, Peiffer L, Kumar R, Schrama D, Hoffmann D, Schadendorf D, Becker JC. Spassova I, et al. Among authors: kubat l. Clin Cancer Res. 2020 May 1;26(9):2257-2267. doi: 10.1158/1078-0432.CCR-19-2244. Epub 2020 Jan 13. Clin Cancer Res. 2020. PMID: 31932494
13 results