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PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs.
Shan Y, Liang Z, Xing Q, Zhang T, Wang B, Tian S, Huang W, Zhang Y, Yao J, Zhu Y, Huang K, Liu Y, Wang X, Chen Q, Zhang J, Shang B, Li S, Shi X, Liao B, Zhang C, Lai K, Zhong X, Shu X, Wang J, Yao H, Chen J, Pei D, Pan G. Shan Y, et al. Nat Commun. 2017 Sep 22;8(1):672. doi: 10.1038/s41467-017-00668-4. Nat Commun. 2017. PMID: 28939884 Free PMC article.
JMJD3 and UTX determine fidelity and lineage specification of human neural progenitor cells.
Shan Y, Zhang Y, Zhao Y, Wang T, Zhang J, Yao J, Ma N, Liang Z, Huang W, Huang K, Zhang T, Su Z, Chen Q, Zhu Y, Wu C, Zhou T, Sun W, Wei Y, Zhang C, Li C, Su S, Liao B, Zhong M, Zhong X, Nie J, Pei D, Pan G. Shan Y, et al. Nat Commun. 2020 Jan 20;11(1):382. doi: 10.1038/s41467-019-14028-x. Nat Commun. 2020. PMID: 31959746 Free PMC article.
BMI1 enables interspecies chimerism with human pluripotent stem cells.
Huang K, Zhu Y, Ma Y, Zhao B, Fan N, Li Y, Song H, Chu S, Ouyang Z, Zhang Q, Xing Q, Lai C, Li N, Zhang T, Gu J, Kang B, Shan Y, Lai K, Huang W, Mai Y, Wang Q, Li J, Lin A, Zhang Y, Zhong X, Liao B, Lai L, Chen J, Pei D, Pan G. Huang K, et al. Among authors: shan y. Nat Commun. 2018 Nov 7;9(1):4649. doi: 10.1038/s41467-018-07098-w. Nat Commun. 2018. PMID: 30405129 Free PMC article.
Vitamin C-dependent lysine demethylase 6 (KDM6)-mediated demethylation promotes a chromatin state that supports the endothelial-to-hematopoietic transition.
Zhang T, Huang K, Zhu Y, Wang T, Shan Y, Long B, Li Y, Chen Q, Wang P, Zhao S, Li D, Wu C, Kang B, Gu J, Mai Y, Wang Q, Li J, Zhang Y, Liang Z, Guo L, Wu F, Su S, Wang J, Gao M, Zhong X, Liao B, Chen J, Zhang X, Shu X, Pei D, Nie J, Pan G. Zhang T, et al. Among authors: shan y. J Biol Chem. 2019 Sep 13;294(37):13657-13670. doi: 10.1074/jbc.RA119.009757. Epub 2019 Jul 24. J Biol Chem. 2019. PMID: 31341023 Free PMC article.
3,612 results