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H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs.
Chen J, Liu H, Liu J, Qi J, Wei B, Yang J, Liang H, Chen Y, Chen J, Wu Y, Guo L, Zhu J, Zhao X, Peng T, Zhang Y, Chen S, Li X, Li D, Wang T, Pei D. Chen J, et al. Among authors: chen s, chen y. Nat Genet. 2013 Jan;45(1):34-42. doi: 10.1038/ng.2491. Epub 2012 Dec 2. Nat Genet. 2013. PMID: 23202127
Vitamin C modulates TET1 function during somatic cell reprogramming.
Chen J, Guo L, Zhang L, Wu H, Yang J, Liu H, Wang X, Hu X, Gu T, Zhou Z, Liu J, Liu J, Wu H, Mao SQ, Mo K, Li Y, Lai K, Qi J, Yao H, Pan G, Xu GL, Pei D. Chen J, et al. Nat Genet. 2013 Dec;45(12):1504-9. doi: 10.1038/ng.2807. Epub 2013 Oct 27. Nat Genet. 2013. PMID: 24162740
The oncogene c-Jun impedes somatic cell reprogramming.
Liu J, Han Q, Peng T, Peng M, Wei B, Li D, Wang X, Yu S, Yang J, Cao S, Huang K, Hutchins AP, Liu H, Kuang J, Zhou Z, Chen J, Wu H, Guo L, Chen Y, Chen Y, Li X, Wu H, Liao B, He W, Song H, Yao H, Pan G, Chen J, Pei D. Liu J, et al. Among authors: chen j, chen y. Nat Cell Biol. 2015 Jul;17(7):856-67. doi: 10.1038/ncb3193. Epub 2015 Jun 22. Nat Cell Biol. 2015. PMID: 26098572
Gadd45a is a heterochromatin relaxer that enhances iPS cell generation.
Chen K, Long Q, Wang T, Zhao D, Zhou Y, Qi J, Wu Y, Li S, Chen C, Zeng X, Yang J, Zhou Z, Qin W, Liu X, Li Y, Li Y, Huang X, Qin D, Chen J, Pan G, Schöler HR, Xu G, Liu X, Pei D. Chen K, et al. Among authors: chen j, chen c. EMBO Rep. 2016 Nov;17(11):1641-1656. doi: 10.15252/embr.201642402. Epub 2016 Oct 4. EMBO Rep. 2016. PMID: 27702986 Free PMC article.
137,491 results
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