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Transcriptomic analysis of BM-MSCs identified EGR1 as a transcription factor to fully exploit their therapeutic potential.
Santi L, Beretta S, Berti M, Savoia EO, Passerini L, Mancino M, De Ponti G, Alberti G, Quaranta P, Basso-Ricci L, Avanzini MA, Merelli I, Scala S, Ferrari S, Aiuti A, Bernardo ME, Crippa S. Santi L, et al. Among authors: quaranta p. Biochim Biophys Acta Mol Cell Res. 2024 Dec;1871(8):119818. doi: 10.1016/j.bbamcr.2024.119818. Epub 2024 Aug 19. Biochim Biophys Acta Mol Cell Res. 2024. PMID: 39168411 Free PMC article.
Hematopoietic reconstitution dynamics of mobilized- and bone marrow-derived human hematopoietic stem cells after gene therapy.
Scala S, Ferrua F, Basso-Ricci L, Dionisio F, Omrani M, Quaranta P, Jofra Hernandez R, Del Core L, Benedicenti F, Monti I, Giannelli S, Fraschetta F, Darin S, Albertazzi E, Galimberti S, Montini E, Calabria A, Cicalese MP, Aiuti A. Scala S, et al. Among authors: quaranta p. Nat Commun. 2023 May 27;14(1):3068. doi: 10.1038/s41467-023-38448-y. Nat Commun. 2023. PMID: 37244942 Free PMC article. Clinical Trial.
Circulating hematopoietic stem/progenitor cell subsets contribute to human hematopoietic homeostasis.
Quaranta P, Basso-Ricci L, Jofra Hernandez R, Pacini G, Naldini MM, Barcella M, Seffin L, Pais G, Spinozzi G, Benedicenti F, Pietrasanta C, Cheong JG, Ronchi A, Pugni L, Dionisio F, Monti I, Giannelli S, Darin S, Fraschetta F, Barera G, Ferrua F, Calbi V, Ometti M, Di Micco R, Mosca F, Josefowicz SZ, Montini E, Calabria A, Bernardo ME, Cicalese MP, Gentner B, Merelli I, Aiuti A, Scala S. Quaranta P, et al. Blood. 2024 May 9;143(19):1937-1952. doi: 10.1182/blood.2023022666. Blood. 2024. PMID: 38446574 Free PMC article. Clinical Trial.
A GLB1 transgene with enhanced therapeutic potential for the preclinical development of ex-vivo gene therapy to treat mucopolysaccharidosis type IVB.
Crippa S, Alberti G, Passerini L, Savoia EO, Mancino M, De Ponti G, Santi L, Berti M, Testa M, Hernandez RJ, Quaranta P, Ceriotti S, Visigalli I, Morrone A, Paoli A, Forni C, Scala S, Degano M, Staiano L, Gregori S, Aiuti A, Bernardo ME. Crippa S, et al. Among authors: quaranta p. Mol Ther Methods Clin Dev. 2024 Aug 6;32(3):101313. doi: 10.1016/j.omtm.2024.101313. eCollection 2024 Sep 12. Mol Ther Methods Clin Dev. 2024. PMID: 39282079 Free PMC article.
Early bone marrow alterations in patients with adenosine deaminase 2 deficiency across disease phenotypes and severities.
Bulté D, Barzaghi F, Mesa-Nuñez C, Rigamonti C, Basso-Ricci L, Visconti C, Crippa S, Pettinato E, Gilioli D, Milani R, Quaranta P, Caorsi R, Cafaro A, Cangemi G, Lupia M, Schena F, Grossi A, Di Colo G, Federici S, Insalaco A, De Benedetti F, Marktel S, Di Micco R, Bernardo ME, Scala S, Cicalese MP, Conti F, Miano M, Gattorno M, Dufour C, Aiuti A, Mortellaro A. Bulté D, et al. Among authors: quaranta p. J Allergy Clin Immunol. 2024 Sep 14:S0091-6749(24)00945-X. doi: 10.1016/j.jaci.2024.09.007. Online ahead of print. J Allergy Clin Immunol. 2024. PMID: 39284370 Free article.
Author Correction: Selection and characterization of human scFvs targeting the SARS-CoV-2 nucleocapsid protein isolated from antibody libraries of COVID-19 patients.
Lisi S, Malerba F, Quaranta P, Florio R, Vitaloni O, Monaca E, Ercole BB, Bitonti AR, Del Perugia O, Mignanelli M, Perrera P, Sabbatella R, Raimondi F, Piazza CR, Moles A, Alfano C, Pistello M, Cattaneo A. Lisi S, et al. Among authors: quaranta p. Sci Rep. 2024 Aug 1;14(1):17800. doi: 10.1038/s41598-024-68554-w. Sci Rep. 2024. PMID: 39090189 Free PMC article. No abstract available.
Selection and characterization of human scFvs targeting the SARS-CoV-2 nucleocapsid protein isolated from antibody libraries of COVID-19 patients.
Lisi S, Malerba F, Quaranta P, Florio R, Vitaloni O, Monaca E, Bruni Ercole B, Bitonti AR, Del Perugia O, Mignanelli M, Perrera P, Sabbatella R, Raimondi F, Piazza CR, Moles A, Alfano C, Pistello M, Cattaneo A. Lisi S, et al. Among authors: quaranta p. Sci Rep. 2024 Jul 9;14(1):15864. doi: 10.1038/s41598-024-66558-0. Sci Rep. 2024. PMID: 38982108 Free PMC article.
The purinergic receptor P2X7 and the NLRP3 inflammasome are druggable host factors required for SARS-CoV-2 infection.
Lécuyer D, Nardacci R, Tannous D, Gutierrez-Mateyron E, Deva Nathan A, Subra F, Di Primio C, Quaranta P, Petit V, Richetta C, Mostefa-Kara A, Del Nonno F, Falasca L, Marlin R, Maisonnasse P, Delahousse J, Pascaud J, Deprez E, Naigeon M, Chaput N, Paci A, Saada V, Ghez D, Mariette X, Costa M, Pistello M, Allouch A, Delelis O, Piacentini M, Le Grand R, Perfettini JL. Lécuyer D, et al. Among authors: quaranta p. Front Immunol. 2023 Oct 18;14:1270081. doi: 10.3389/fimmu.2023.1270081. eCollection 2023. Front Immunol. 2023. PMID: 37920468 Free PMC article.
49 results