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Integrative Multiomics in the Lung Reveals a Protective Role of Asporin in Pulmonary Arterial Hypertension.
Hong J, Medzikovic L, Sun W, Wong B, Ruffenach G, Rhodes CJ, Brownstein A, Liang LL, Aryan L, Li M, Vadgama A, Kurt Z, Schwantes-An TH, Mickler EA, Gräf S, Eyries M, Lutz KA, Pauciulo MW, Trembath RC, Perros F, Montani D, Morrell NW, Soubrier F, Wilkins MR, Nichols WC, Aldred MA, Desai AA, Trégouët DA, Umar S, Saggar R, Channick R, Tuder RM, Geraci MW, Stearman RS, Yang X, Eghbali M. Hong J, et al. Among authors: yang x. Circulation. 2024 Oct 15;150(16):1268-1287. doi: 10.1161/CIRCULATIONAHA.124.069864. Epub 2024 Aug 21. Circulation. 2024. PMID: 39167456
Single-Cell Study of Two Rat Models of Pulmonary Arterial Hypertension Reveals Connections to Human Pathobiology and Drug Repositioning.
Hong J, Arneson D, Umar S, Ruffenach G, Cunningham CM, Ahn IS, Diamante G, Bhetraratana M, Park JF, Said E, Huynh C, Le T, Medzikovic L, Humbert M, Soubrier F, Montani D, Girerd B, Trégouët DA, Channick R, Saggar R, Eghbali M, Yang X. Hong J, et al. Among authors: yang x. Am J Respir Crit Care Med. 2021 Apr 15;203(8):1006-1022. doi: 10.1164/rccm.202006-2169OC. Am J Respir Crit Care Med. 2021. PMID: 33021809 Free PMC article.
Oral 15-Hydroxyeicosatetraenoic Acid Induces Pulmonary Hypertension in Mice by Triggering T Cell-Dependent Endothelial Cell Apoptosis.
Ruffenach G, O'Connor E, Vaillancourt M, Hong J, Cao N, Sarji S, Moazeni S, Papesh J, Grijalva V, Cunningham CM, Shu L, Chattopadhyay A, Tiwari S, Mercier O, Perros F, Umar S, Yang X, Gomes AV, Fogelman AM, Reddy ST, Eghbali M. Ruffenach G, et al. Among authors: yang x. Hypertension. 2020 Sep;76(3):985-996. doi: 10.1161/HYPERTENSIONAHA.120.14697. Epub 2020 Jul 27. Hypertension. 2020. PMID: 32713273 Free PMC article.
Transcription Factor MAFF (MAF Basic Leucine Zipper Transcription Factor F) Regulates an Atherosclerosis Relevant Network Connecting Inflammation and Cholesterol Metabolism.
von Scheidt M, Zhao Y, de Aguiar Vallim TQ, Che N, Wierer M, Seldin MM, Franzén O, Kurt Z, Pang S, Bongiovanni D, Yamamoto M, Edwards PA, Ruusalepp A, Kovacic JC, Mann M, Björkegren JLM, Lusis AJ, Yang X, Schunkert H. von Scheidt M, et al. Among authors: yang x. Circulation. 2021 May 4;143(18):1809-1823. doi: 10.1161/CIRCULATIONAHA.120.050186. Epub 2021 Feb 25. Circulation. 2021. PMID: 33626882 Free PMC article.
Shared genetic regulatory networks for cardiovascular disease and type 2 diabetes in multiple populations of diverse ethnicities in the United States.
Shu L, Chan KHK, Zhang G, Huan T, Kurt Z, Zhao Y, Codoni V, Trégouët DA; Cardiogenics Consortium; Yang J, Wilson JG, Luo X, Levy D, Lusis AJ, Liu S, Yang X. Shu L, et al. Among authors: yang x, yang j. PLoS Genet. 2017 Sep 28;13(9):e1007040. doi: 10.1371/journal.pgen.1007040. eCollection 2017 Sep. PLoS Genet. 2017. PMID: 28957322 Free PMC article.
Shared and distinct pathways and networks genetically linked to coronary artery disease between human and mouse.
Kurt Z, Cheng J, McQuillen CN, Saleem Z, Hsu N, Jiang N, Barrere-Cain R, Pan C, Franzen O, Koplev S, Wang S, Bjorkegren J, Lusis AJ, Blencowe M, Yang X. Kurt Z, et al. Among authors: yang x. bioRxiv [Preprint]. 2023 Sep 20:2023.06.08.544148. doi: 10.1101/2023.06.08.544148. bioRxiv. 2023. Update in: Elife. 2023 Dec 07;12:RP88266. doi: 10.7554/eLife.88266 PMID: 37333408 Free PMC article. Updated. Preprint.
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