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PCPE-1, a brown adipose tissue-derived cytokine, promotes obesity-induced liver fibrosis.
Hsiao YT, Yoshida Y, Okuda S, Abe M, Mizuno S, Takahashi S, Nakagami H, Morishita R, Kamimura K, Terai S, Aung TM, Li J, Furihata T, Tang JY, Walsh K, Ishigami A, Minamino T, Shimizu I. Hsiao YT, et al. Among authors: abe m. EMBO J. 2024 Nov;43(21):4846-4869. doi: 10.1038/s44318-024-00196-0. Epub 2024 Aug 19. EMBO J. 2024. PMID: 39160276 Free PMC article.
Forward-genetics analysis of sleep in randomly mutagenized mice.
Funato H, Miyoshi C, Fujiyama T, Kanda T, Sato M, Wang Z, Ma J, Nakane S, Tomita J, Ikkyu A, Kakizaki M, Hotta-Hirashima N, Kanno S, Komiya H, Asano F, Honda T, Kim SJ, Harano K, Muramoto H, Yonezawa T, Mizuno S, Miyazaki S, Connor L, Kumar V, Miura I, Suzuki T, Watanabe A, Abe M, Sugiyama F, Takahashi S, Sakimura K, Hayashi Y, Liu Q, Kume K, Wakana S, Takahashi JS, Yanagisawa M. Funato H, et al. Among authors: abe m. Nature. 2016 Nov 17;539(7629):378-383. doi: 10.1038/nature20142. Epub 2016 Nov 2. Nature. 2016. PMID: 27806374 Free PMC article.
Induction of Mutant Sik3Sleepy Allele in Neurons in Late Infancy Increases Sleep Need.
Iwasaki K, Fujiyama T, Nakata S, Park M, Miyoshi C, Hotta-Hirashima N, Ikkyu A, Kakizaki M, Sugiyama F, Mizuno S, Abe M, Sakimura K, Takahashi S, Funato H, Yanagisawa M. Iwasaki K, et al. Among authors: abe m. J Neurosci. 2021 Mar 24;41(12):2733-2746. doi: 10.1523/JNEUROSCI.1004-20.2020. Epub 2021 Feb 8. J Neurosci. 2021. PMID: 33558433 Free PMC article.
Loss of Atg2b and Gskip Impairs the Maintenance of the Hematopoietic Stem Cell Pool Size.
Sakai SS, Hasegawa A, Ishimura R, Tamura N, Kageyama S, Komatsu-Hirota S, Abe M, Ling Y, Okuda S, Funayama M, Kikkawa M, Miura Y, Sakimura K, Narita I, Waguri S, Shimizu R, Komatsu M. Sakai SS, et al. Among authors: abe m. Mol Cell Biol. 2022 Jan 20;42(1):e0002421. doi: 10.1128/MCB.00024-21. Epub 2021 Nov 8. Mol Cell Biol. 2022. PMID: 34748402 Free PMC article.
Coagulation factors promote brown adipose tissue dysfunction and abnormal systemic metabolism in obesity.
Hayashi Y, Shimizu I, Yoshida Y, Ikegami R, Suda M, Katsuumi G, Fujiki S, Ozaki K, Abe M, Sakimura K, Okuda S, Hayano T, Nakamura K, Walsh K, Jespersen NZ, Nielsen S, Scheele C, Minamino T. Hayashi Y, et al. Among authors: abe m. iScience. 2022 Jun 7;25(7):104547. doi: 10.1016/j.isci.2022.104547. eCollection 2022 Jul 15. iScience. 2022. PMID: 35754738 Free PMC article.
Brown adipose tissue dysfunction promotes heart failure via a trimethylamine N-oxide-dependent mechanism.
Yoshida Y, Shimizu I, Shimada A, Nakahara K, Yanagisawa S, Kubo M, Fukuda S, Ishii C, Yamamoto H, Ishikawa T, Kano K, Aoki J, Katsuumi G, Suda M, Ozaki K, Yoshida Y, Okuda S, Ohta S, Okamoto S, Minokoshi Y, Oda K, Sasaoka T, Abe M, Sakimura K, Kubota Y, Yoshimura N, Kajimura S, Zuriaga M, Walsh K, Soga T, Minamino T. Yoshida Y, et al. Among authors: abe m. Sci Rep. 2022 Sep 1;12(1):14883. doi: 10.1038/s41598-022-19245-x. Sci Rep. 2022. PMID: 36050466 Free PMC article.
SGLT2 inhibition eliminates senescent cells and alleviates pathological aging.
Katsuumi G, Shimizu I, Suda M, Yoshida Y, Furihata T, Joki Y, Hsiao CL, Jiaqi L, Fujiki S, Abe M, Sugimoto M, Soga T, Minamino T. Katsuumi G, et al. Among authors: abe m. Nat Aging. 2024 Jul;4(7):926-938. doi: 10.1038/s43587-024-00642-y. Epub 2024 May 30. Nat Aging. 2024. PMID: 38816549 Free PMC article.
p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response.
Kageyama S, Gudmundsson SR, Sou YS, Ichimura Y, Tamura N, Kazuno S, Ueno T, Miura Y, Noshiro D, Abe M, Mizushima T, Miura N, Okuda S, Motohashi H, Lee JA, Sakimura K, Ohe T, Noda NN, Waguri S, Eskelinen EL, Komatsu M. Kageyama S, et al. Among authors: abe m. Nat Commun. 2021 Jan 4;12(1):16. doi: 10.1038/s41467-020-20185-1. Nat Commun. 2021. PMID: 33397898 Free PMC article.
Activin a Receptor Type 2A Mutation Affects the Tumor Biology of Microsatellite Instability-High Gastric Cancer.
Yuza K, Nagahashi M, Ichikawa H, Hanyu T, Nakajima M, Shimada Y, Ishikawa T, Sakata J, Takeuchi S, Okuda S, Matsuda Y, Abe M, Sakimura K, Takabe K, Wakai T. Yuza K, et al. Among authors: abe m. J Gastrointest Surg. 2021 Sep;25(9):2231-2241. doi: 10.1007/s11605-020-04889-9. Epub 2021 Jan 8. J Gastrointest Surg. 2021. PMID: 33420656 Free PMC article.
Phosphorylation of phase-separated p62 bodies by ULK1 activates a redox-independent stress response.
Ikeda R, Noshiro D, Morishita H, Takada S, Kageyama S, Fujioka Y, Funakoshi T, Komatsu-Hirota S, Arai R, Ryzhii E, Abe M, Koga T, Motohashi H, Nakao M, Sakimura K, Horii A, Waguri S, Ichimura Y, Noda NN, Komatsu M. Ikeda R, et al. Among authors: abe m. EMBO J. 2023 Jul 17;42(14):e113349. doi: 10.15252/embj.2022113349. Epub 2023 Jun 12. EMBO J. 2023. PMID: 37306101 Free PMC article.
6,259 results