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Randomized phase II study of bevacizumab with weekly anetumab ravtansine or weekly paclitaxel in platinum-resistant/refractory high grade ovarian cancer (NCI trial).
Alqaisi HA, Cohn DE, Chern JY, Duska LR, Jewell A, Corr BR, Winer IS, Girda E, Crispens MA, Dhani NC, Madariaga A, Grant RC, Malaguti M, Lee C, Bowering V, Wong H, Poothullil A, Speers V, Wang L, Bedard PL, Brady JC, Nixon AB, Chen L, O'Connor C, Zamboni W, McKee T, Moscow JA, Oza AM, Lheureux S. Alqaisi HA, et al. Among authors: grant rc. Clin Cancer Res. 2025 Jan 21. doi: 10.1158/1078-0432.CCR-24-3128. Online ahead of print. Clin Cancer Res. 2025. PMID: 39836408
Functional variants in the cystic fibrosis transmembrane conductance regulator (CFTR) gene are associated with increased risk of colorectal cancer.
Prizment A, Standafer A, Qu C, Beutel KM, Wang S, Huang WY, Lindblom A, Pearlman R, Van Guelpen B, Wolk A, Buchanan DD, Grant RC, Schmit SL, Platz EA, Joshu CE, Couper DJ, Peters U, Starr TK, Scott P, Pankratz N. Prizment A, et al. Among authors: grant rc. Hum Mol Genet. 2025 Jan 17:ddaf007. doi: 10.1093/hmg/ddaf007. Online ahead of print. Hum Mol Genet. 2025. PMID: 39825500
Adenomas from individuals with pathogenic biallelic variants in the MUTYH and NTHL1 genes demonstrate base excision repair tumour mutational signature profiles similar to colorectal cancers, expanding potential diagnostic and variant classification applications.
Walker R, Joo JE, Mahmood K, Clendenning M, Como J, Preston SG, Joseland S, Pope BJ, Medeiros ABD, Murillo BV, Pachter N, Sweet K, Spigelman AD, Groves A, Gleeson M, Bernatowicz K, Poplawski N, Andrews L, Healey E, Gallinger S, Grant RC, Win AK, Hopper JL, Jenkins MA, Torrezan GT, Rosty C, Macrae FA, Winship IM, Buchanan DD, Georgeson P. Walker R, et al. Among authors: grant rc. Transl Oncol. 2025 Feb;52:102266. doi: 10.1016/j.tranon.2024.102266. Epub 2025 Jan 9. Transl Oncol. 2025. PMID: 39793275 Free article.
Author Correction: Profibrotic monocyte-derived alveolar macrophages are expanded in patients with persistent respiratory symptoms and radiographic abnormalities after COVID-19.
Bailey JI, Puritz CH, Senkow KJ, Markov NS, Diaz E, Jonasson E, Yu Z, Swaminathan S, Lu Z, Fenske S, Grant RA, Abdala-Valencia H, Mylvaganam RJ, Ludwig A, Miller J, Cumming RI, Tighe RM, Gowdy KM, Kalhan R, Jain M, Bharat A, Kurihara C, San Jose Estepar R, San Jose Estepar R, Washko GR, Shilatifard A, Sznajder JI, Ridge KM, Budinger GRS, Braun R, Misharin AV, Sala MA. Bailey JI, et al. Among authors: grant ra. Nat Immunol. 2025 Jan 7. doi: 10.1038/s41590-025-02076-z. Online ahead of print. Nat Immunol. 2025. PMID: 39774409 No abstract available.
Association between somatic microsatellite instability, hypermutation status, and specific T cell subsets in colorectal cancer tumors.
Thomas CE, Takashima Y, Wesselink E, Ugai T, Steinfelder RS, Buchanan DD, Qu C, Hsu L, Dias Costa A, Gallinger S, Grant RC, Huyghe JR, Thomas SS, Ogino S, Phipps AI, Nowak JA, Peters U. Thomas CE, et al. Among authors: grant rc. Front Immunol. 2024 Dec 23;15:1505896. doi: 10.3389/fimmu.2024.1505896. eCollection 2024. Front Immunol. 2024. PMID: 39763680 Free PMC article.
2,413 results