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Autism-associated CHD8 controls reactive gliosis and neuroinflammation via remodeling chromatin in astrocytes.
Megagiannis P, Mei Y, Yan RE, Yuan L, Wilde JJ, Eckersberg H, Suresh R, Tan X, Chen H, Farmer WT, Cha K, Le PU, Catoire H, Rochefort D, Kwan T, Yee BA, Dion P, Krishnaswamy A, Cloutier JF, Stifani S, Petrecca K, Yeo GW, Murai KK, Feng G, Rouleau GA, Ideker T, Sanjana NE, Zhou Y. Megagiannis P, et al. Among authors: murai kk. Cell Rep. 2024 Aug 27;43(8):114637. doi: 10.1016/j.celrep.2024.114637. Epub 2024 Aug 17. Cell Rep. 2024. PMID: 39154337 Free article.
Resolving Astrocyte Heterogeneity in the CNS.
Farmer WT, Murai K. Farmer WT, et al. Front Cell Neurosci. 2017 Sep 27;11:300. doi: 10.3389/fncel.2017.00300. eCollection 2017. Front Cell Neurosci. 2017. PMID: 29021743 Free PMC article. Review.
Characterization of Vimentin-Immunoreactive Astrocytes in the Human Brain.
O'Leary LA, Davoli MA, Belliveau C, Tanti A, Ma JC, Farmer WT, Turecki G, Murai KK, Mechawar N. O'Leary LA, et al. Among authors: murai kk. Front Neuroanat. 2020 Jul 30;14:31. doi: 10.3389/fnana.2020.00031. eCollection 2020. Front Neuroanat. 2020. PMID: 32848635 Free PMC article.
Human iPSC-derived Down syndrome astrocytes display genome-wide perturbations in gene expression, an altered adhesion profile, and increased cellular dynamics.
Ponroy Bally B, Farmer WT, Jones EV, Jessa S, Kacerovsky JB, Mayran A, Peng H, Lefebvre JL, Drouin J, Hayer A, Ernst C, Murai KK. Ponroy Bally B, et al. Among authors: murai kk. Hum Mol Genet. 2020 Mar 27;29(5):785-802. doi: 10.1093/hmg/ddaa003. Hum Mol Genet. 2020. PMID: 31943018 Free PMC article.
Neurons diversify astrocytes in the adult brain through sonic hedgehog signaling.
Farmer WT, Abrahamsson T, Chierzi S, Lui C, Zaelzer C, Jones EV, Bally BP, Chen GG, Théroux JF, Peng J, Bourque CW, Charron F, Ernst C, Sjöström PJ, Murai KK. Farmer WT, et al. Among authors: murai kk. Science. 2016 Feb 19;351(6275):849-54. doi: 10.1126/science.aab3103. Science. 2016. PMID: 26912893
74 results