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Impact of JQ1 treatment on seizures, hippocampal gene expression, and gliosis in a mouse model of temporal lobe epilepsy.
Harnett A, Mathoux J, Wilson MM, Heiland M, Mamad O, Srinivas S, Sanfeliu A, Sanz-Rodriguez A, How KLE, Delanty N, Cryan J, Brett FM, Farrell MA, O'Brien DF, Henshall DC, Brennan GP. Harnett A, et al. Among authors: henshall dc. Eur J Neurosci. 2024 Sep;60(6):5266-5283. doi: 10.1111/ejn.16499. Epub 2024 Aug 16. Eur J Neurosci. 2024. PMID: 39149798
Epileptic tolerance is associated with enduring neuroprotection and uncoupling of the relationship between CA3 damage, neuropeptide Y rearrangement and spontaneous seizures following intra-amygdala kainic acid-induced status epilepticus in mice.
Jimenez-Mateos EM, Mouri G, Conroy RM, Henshall DC. Jimenez-Mateos EM, et al. Among authors: henshall dc. Neuroscience. 2010 Dec 1;171(2):556-65. doi: 10.1016/j.neuroscience.2010.09.003. Epub 2010 Sep 17. Neuroscience. 2010. PMID: 20837105
Reduced mature microRNA levels in association with dicer loss in human temporal lobe epilepsy with hippocampal sclerosis.
McKiernan RC, Jimenez-Mateos EM, Bray I, Engel T, Brennan GP, Sano T, Michalak Z, Moran C, Delanty N, Farrell M, O'Brien D, Meller R, Simon RP, Stallings RL, Henshall DC. McKiernan RC, et al. Among authors: henshall dc. PLoS One. 2012;7(5):e35921. doi: 10.1371/journal.pone.0035921. Epub 2012 May 15. PLoS One. 2012. PMID: 22615744 Free PMC article.
Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects.
Jimenez-Mateos EM, Engel T, Merino-Serrais P, McKiernan RC, Tanaka K, Mouri G, Sano T, O'Tuathaigh C, Waddington JL, Prenter S, Delanty N, Farrell MA, O'Brien DF, Conroy RM, Stallings RL, DeFelipe J, Henshall DC. Jimenez-Mateos EM, et al. Among authors: henshall dc. Nat Med. 2012 Jul;18(7):1087-94. doi: 10.1038/nm.2834. Nat Med. 2012. PMID: 22683779 Free PMC article.
238 results