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Impact of JQ1 treatment on seizures, hippocampal gene expression, and gliosis in a mouse model of temporal lobe epilepsy.
Harnett A, Mathoux J, Wilson MM, Heiland M, Mamad O, Srinivas S, Sanfeliu A, Sanz-Rodriguez A, How KLE, Delanty N, Cryan J, Brett FM, Farrell MA, O'Brien DF, Henshall DC, Brennan GP. Harnett A, et al. Among authors: heiland m. Eur J Neurosci. 2024 Sep;60(6):5266-5283. doi: 10.1111/ejn.16499. Epub 2024 Aug 16. Eur J Neurosci. 2024. PMID: 39149798
Brain cell-specific origin of circulating microRNA biomarkers in experimental temporal lobe epilepsy.
Brindley E, Heiland M, Mooney C, Diviney M, Mamad O, Hill TDM, Yan Y, Venø MT, Reschke CR, Batool A, Langa E, Sanz-Rodriguez A, Heller JP, Morris G, Conboy K, Kjems J, Brennan GP, Henshall DC. Brindley E, et al. Among authors: heiland m. Front Mol Neurosci. 2023 Sep 22;16:1230942. doi: 10.3389/fnmol.2023.1230942. eCollection 2023. Front Mol Neurosci. 2023. PMID: 37808470 Free PMC article.
Genome-wide microRNA profiling of plasma from three different animal models identifies biomarkers of temporal lobe epilepsy.
Brennan GP, Bauer S, Engel T, Jimenez-Mateos EM, Del Gallo F, Hill TDM, Connolly NMC, Costard LS, Neubert V, Salvetti B, Sanz-Rodriguez A, Heiland M, Mamad O, Brindley E, Norwood B, Batool A, Raoof R, El-Naggar H, Reschke CR, Delanty N, Prehn JHM, Fabene P, Mooney C, Rosenow F, Henshall DC. Brennan GP, et al. Among authors: heiland m. Neurobiol Dis. 2020 Oct;144:105048. doi: 10.1016/j.nbd.2020.105048. Epub 2020 Aug 13. Neurobiol Dis. 2020. PMID: 32800995 Free article.
Anti-seizure effects of JNJ-54175446 in the intra-amygdala kainic acid model of drug-resistant temporal lobe epilepsy in mice.
Mamad O, Heiland M, Lindner AU, Hill TDM, Ronroy RM, Rentrup K, Sanz-Rodriguez A, Langa E, Heller JP, Moreno O, Llop J, Bhattacharya A, Palmer JA, Ceusters M, Engel T, Henshall DC. Mamad O, et al. Among authors: heiland m. Front Pharmacol. 2024 Jan 8;14:1308478. doi: 10.3389/fphar.2023.1308478. eCollection 2023. Front Pharmacol. 2024. PMID: 38259288 Free PMC article.
MicroRNA-335-5p suppresses voltage-gated sodium channel expression and may be a target for seizure control.
Heiland M, Connolly NMC, Mamad O, Nguyen NT, Kesavan JC, Langa E, Fanning K, Sanfeliu A, Yan Y, Su J, Venø MT, Costard LS, Neubert V, Engel T, Hill TDM, Freiman TM, Mahesh A, Tiwari VK, Rosenow F, Bauer S, Kjems J, Morris G, Henshall DC. Heiland M, et al. Proc Natl Acad Sci U S A. 2023 Jul 25;120(30):e2216658120. doi: 10.1073/pnas.2216658120. Epub 2023 Jul 18. Proc Natl Acad Sci U S A. 2023. PMID: 37463203 Free PMC article.
Opposing effects of the purinergic P2X7 receptor on seizures in neurons and microglia in male mice.
Alves M, Gil B, Villegas-Salmerón J, Salari V, Martins-Ferreira R, Arribas Blázquez M, Menéndez Méndez A, Da Rosa Gerbatin R, Smith J, de Diego-Garcia L, Conte G, Sierra-Marquez J, Merino Serrais P, Mitra M, Fernandez Martin A, Wang Y, Kesavan J, Melia C, Parras A, Beamer E, Zimmer B, Heiland M, Cavanagh B, Parcianello Cipolat R, Morgan J, Teng X, Prehn JHM, Fabene PF, Bertini G, Artalejo AR, Ballestar E, Nicke A, Olivos-Oré LA, Connolly NMC, Henshall DC, Engel T. Alves M, et al. Among authors: heiland m. Brain Behav Immun. 2024 Aug;120:121-140. doi: 10.1016/j.bbi.2024.05.023. Epub 2024 May 20. Brain Behav Immun. 2024. PMID: 38777288 Free article.
RET overexpression leads to increased brain metastatic competency in luminal breast cancer.
Jagust P, Powell AM, Ola M, Watson L, de Pablos-Aragoneses A, García-Gómez P, Fallon R, Bane F, Heiland M, Morris G, Cavanagh B, McGrath J, Ottaviani D, Hegarty A, Cocchiglia S, Sweeney KJ, MacNally S, Brett FM, Cryan J, Beausang A, Morris P, Valiente M, Hill ADK, Varešlija D, Young LS. Jagust P, et al. Among authors: heiland m. J Natl Cancer Inst. 2024 Oct 1;116(10):1632-1644. doi: 10.1093/jnci/djae091. J Natl Cancer Inst. 2024. PMID: 38852945 Free PMC article.
371 results