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An ADAR1 dsRBD3-PKR kinase domain interaction on dsRNA inhibits PKR activation.
Sinigaglia K, Cherian A, Du Q, Lacovich V, Vukić D, Melicherová J, Linhartova P, Zerad L, Stejskal S, Malik R, Prochazka J, Bondurand N, Sedláček R, O'Connell MA, Keegan LP. Sinigaglia K, et al. Among authors: malik r. Cell Rep. 2024 Aug 27;43(8):114618. doi: 10.1016/j.celrep.2024.114618. Epub 2024 Aug 14. Cell Rep. 2024. PMID: 39146181 Free article.
Structural and functional basis of mammalian microRNA biogenesis by Dicer.
Zapletal D, Taborska E, Pasulka J, Malik R, Kubicek K, Zanova M, Much C, Sebesta M, Buccheri V, Horvat F, Jenickova I, Prochazkova M, Prochazka J, Pinkas M, Novacek J, Joseph DF, Sedlacek R, Bernecky C, O'Carroll D, Stefl R, Svoboda P. Zapletal D, et al. Among authors: malik r. Mol Cell. 2022 Nov 3;82(21):4064-4079.e13. doi: 10.1016/j.molcel.2022.10.010. Mol Cell. 2022. PMID: 36332606 Free PMC article.
Functional canonical RNAi in mice expressing a truncated Dicer isoform and long dsRNA.
Buccheri V, Pasulka J, Malik R, Loubalova Z, Taborska E, Horvat F, Roos Kulmann MI, Jenickova I, Prochazka J, Sedlacek R, Svoboda P. Buccheri V, et al. Among authors: malik r. EMBO Rep. 2024 Jul;25(7):2896-2913. doi: 10.1038/s44319-024-00148-z. Epub 2024 May 20. EMBO Rep. 2024. PMID: 38769420 Free PMC article.
Role of Cnot6l in maternal mRNA turnover.
Horvat F, Fulka H, Jankele R, Malik R, Jun M, Solcova K, Sedlacek R, Vlahovicek K, Schultz RM, Svoboda P. Horvat F, et al. Among authors: malik r. Life Sci Alliance. 2018 Jul 16;1(4):e201800084. doi: 10.26508/lsa.201800084. eCollection 2018 Aug. Life Sci Alliance. 2018. PMID: 30456367 Free PMC article.
Regulation of 4E-BP1 activity in the mammalian oocyte.
Jansova D, Koncicka M, Tetkova A, Cerna R, Malik R, Del Llano E, Kubelka M, Susor A. Jansova D, et al. Among authors: malik r. Cell Cycle. 2017 May 19;16(10):927-939. doi: 10.1080/15384101.2017.1295178. Epub 2017 Mar 8. Cell Cycle. 2017. PMID: 28272965 Free PMC article.
Main constraints for RNAi induced by expressed long dsRNA in mouse cells.
Demeter T, Vaskovicova M, Malik R, Horvat F, Pasulka J, Svobodova E, Flemr M, Svoboda P. Demeter T, et al. Among authors: malik r. Life Sci Alliance. 2019 Feb 26;2(1):e201800289. doi: 10.26508/lsa.201800289. Print 2019 Feb. Life Sci Alliance. 2019. PMID: 30808654 Free PMC article.
2,648 results