Lima CD - Search Results

1

Structural basis for transthiolation intermediates in the ubiquitin pathway.

Kochańczyk T, Hann ZS, Lux MC, Delos Reyes AMV, Ji C, Tan DS, Lima CD. Kochańczyk T, et al. Among authors: lima cd. Nature. 2024 Sep;633(8028):216-223. doi: 10.1038/s41586-024-07828-9. Epub 2024 Aug 14. Nature. 2024. PMID: 39143218 Free PMC article.

2

Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex.

Reverter D, Lima CD. Reverter D, et al. Among authors: lima cd. Nature. 2005 Jun 2;435(7042):687-92. doi: 10.1038/nature03588. Nature. 2005. PMID: 15931224 Free PMC article.

3

Designed semisynthetic protein inhibitors of Ub/Ubl E1 activating enzymes.

Lu X, Olsen SK, Capili AD, Cisar JS, Lima CD, Tan DS. Lu X, et al. Among authors: lima cd. J Am Chem Soc. 2010 Feb 17;132(6):1748-9. doi: 10.1021/ja9088549. J Am Chem Soc. 2010. PMID: 20099854 Free PMC article.

4

Active site remodelling accompanies thioester bond formation in the SUMO E1.

Olsen SK, Capili AD, Lu X, Tan DS, Lima CD. Olsen SK, et al. Among authors: lima cd. Nature. 2010 Feb 18;463(7283):906-12. doi: 10.1038/nature08765. Nature. 2010. PMID: 20164921 Free PMC article.

5

Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2.

Armstrong AA, Mohideen F, Lima CD. Armstrong AA, et al. Among authors: lima cd. Nature. 2012 Feb 29;483(7387):59-63. doi: 10.1038/nature10883. Nature. 2012. PMID: 22382979 Free PMC article.

6

Structural basis for catalytic activation by the human ZNF451 SUMO E3 ligase.

Cappadocia L, Pichler A, Lima CD. Cappadocia L, et al. Among authors: lima cd. Nat Struct Mol Biol. 2015 Dec;22(12):968-75. doi: 10.1038/nsmb.3116. Epub 2015 Nov 2. Nat Struct Mol Biol. 2015. PMID: 26524494 Free PMC article.

7

Structural basis for adenylation and thioester bond formation in the ubiquitin E1.

Hann ZS, Ji C, Olsen SK, Lu X, Lux MC, Tan DS, Lima CD. Hann ZS, et al. Among authors: lima cd. Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15475-15484. doi: 10.1073/pnas.1905488116. Epub 2019 Jun 24. Proc Natl Acad Sci U S A. 2019. PMID: 31235585 Free PMC article.

8

Crystal structure of the Schizosaccharomyces pombe U7BR E2-binding region in complex with Ubc7.

Hann ZS, Metzger MB, Weissman AM, Lima CD. Hann ZS, et al. Among authors: lima cd. Acta Crystallogr F Struct Biol Commun. 2019 Aug 1;75(Pt 8):552-560. doi: 10.1107/S2053230X19009786. Epub 2019 Aug 2. Acta Crystallogr F Struct Biol Commun. 2019. PMID: 31397327 Free PMC article.

9

DNA asymmetry promotes SUMO modification of the single-stranded DNA-binding protein RPA.

Cappadocia L, Kochańczyk T, Lima CD. Cappadocia L, et al. Among authors: lima cd. EMBO J. 2021 Nov 15;40(22):e103787. doi: 10.15252/embj.2019103787. Epub 2021 Sep 29. EMBO J. 2021. PMID: 34585421 Free PMC article.

10

Design and Semisynthesis of Biselectrophile-Functionalized Ubiquitin Probes To Investigate Transthioesterification Reactions.

Delos Reyes AMV, Lux MC, Hann ZS, Ji C, Kochańczyk T, DiBello M, Lima CD, Tan DS. Delos Reyes AMV, et al. Among authors: lima cd. Org Lett. 2024 Jun 7;26(22):4594-4599. doi: 10.1021/acs.orglett.4c01102. Epub 2024 May 23. Org Lett. 2024. PMID: 38781175 Free PMC article.

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