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115 results

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Page 1
High expression of oleoyl-ACP hydrolase underpins life-threatening respiratory viral diseases.
Jia X, Crawford JC, Gebregzabher D, Monson EA, Mettelman RC, Wan Y, Ren Y, Chou J, Novak T, McQuilten HA, Clarke M, Bachem A, Foo IJ, Fritzlar S, Carrera Montoya J, Trenerry AM, Nie S, Leeming MG, Nguyen THO, Kedzierski L, Littler DR, Kueh A, Cardamone T, Wong CY, Hensen L, Cabug A, Laguna JG, Agrawal M, Flerlage T, Boyd DF, Van de Velde LA, Habel JR, Loh L, Koay HF, van de Sandt CE, Konstantinov IE, Berzins SP, Flanagan KL, Wakim LM, Herold MJ, Green AM, Smallwood HS, Rossjohn J, Thwaites RS, Chiu C, Scott NE, Mackenzie JM, Bedoui S, Reading PC, Londrigan SL, Helbig KJ, Randolph AG, Thomas PG, Xu J, Wang Z, Chua BY, Kedzierska K. Jia X, et al. Among authors: thwaites rs. Cell. 2024 Aug 22;187(17):4586-4604.e20. doi: 10.1016/j.cell.2024.07.026. Epub 2024 Aug 12. Cell. 2024. PMID: 39137778 Free article.
Nasal cathelicidin is expressed in early life and is increased during mild, but not severe respiratory syncytial virus infection.
Sintoris S, Binkowska JM, Gillan JL, Zuurbier RP, Twynam-Perkins J, Kristensen M, Melrose L, Parga PL, Rodriguez AR, Chu ML, van Boeckel SR, Wildenbeest JG, Bowdish DME, Currie AJ, Thwaites RS, Schwarze J, van Houten MA, Boardman JP, Cunningham S, Bogaert D, Davidson DJ. Sintoris S, et al. Among authors: thwaites rs. Sci Rep. 2024 Jun 17;14(1):13928. doi: 10.1038/s41598-024-64446-1. Sci Rep. 2024. PMID: 38886476 Free PMC article.
Lack of association between HLA and asymptomatic SARS-CoV-2 infection.
Marchal A, Cirulli ET, Neveux I, Bellos E, Thwaites RS, Schiabor Barrett KM, Zhang Y, Nemes-Bokun I, Kalinova M, Catchpole A, Tangye SG, Spaan AN, Lack JB, Ghosn J, Burdet C, Gorochov G, Tubach F, Hausfater P; COVID Human Genetic Effort; COVIDeF Study Group; French COVID Cohort Study Group; CoV-Contact Cohort; COVID-STORM Clinicians; COVID Clinicians; Orchestra Working Group; Amsterdam UMC Covid-19 Biobank; NIAID-USUHS COVID Study Group; Dalgard CL, Zhang SY, Zhang Q, Chiu C, Fellay J, Grzymski JJ, Sancho-Shimizu V, Abel L, Casanova JL, Cobat A, Bolze A. Marchal A, et al. Among authors: thwaites rs. medRxiv [Preprint]. 2023 Dec 8:2023.12.06.23299623. doi: 10.1101/2023.12.06.23299623. medRxiv. 2023. Update in: HGG Adv. 2024 Jul 18;5(3):100300. doi: 10.1016/j.xhgg.2024.100300 PMID: 38168184 Free PMC article. Updated. Preprint.
An ultra-early, transient interferon-associated innate immune response associates with protection from SARS-CoV-2 infection despite exposure.
Fenn J, Madon K, Conibear E, Derelle R, Nevin S, Kundu R, Hakki S, Tregoning JS, Koycheva A, Derqui N, Tolosa-Wright M, Jonnerby J, Wang L, Baldwin S, Pillay TD, Thwaites RS, Luca C, Varro R, Badhan A, Parker E, Rosadas C, McClure M, Tedder R, Taylor G, Lalvani A; INSTINCT Study Investigators. Fenn J, et al. Among authors: thwaites rs. EBioMedicine. 2024 Dec 11;111:105475. doi: 10.1016/j.ebiom.2024.105475. Online ahead of print. EBioMedicine. 2024. PMID: 39667271 Free article.
SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination.
Liew F, Talwar S, Cross A, Willett BJ, Scott S, Logan N, Siggins MK, Swieboda D, Sidhu JK, Efstathiou C, Moore SC, Davis C, Mohamed N, Nunag J, King C, Thompson AAR, Rowland-Jones SL, Docherty AB, Chalmers JD, Ho LP, Horsley A, Raman B, Poinasamy K, Marks M, Kon OM, Howard L, Wootton DG, Dunachie S, Quint JK, Evans RA, Wain LV, Fontanella S, de Silva TI, Ho A, Harrison E, Baillie JK, Semple MG, Brightling C, Thwaites RS, Turtle L, Openshaw PJM; ISARIC4C Investigators; PHOSP-COVID collaborative group. Liew F, et al. Among authors: thwaites rs. EBioMedicine. 2023 Jan;87:104402. doi: 10.1016/j.ebiom.2022.104402. Epub 2022 Dec 19. EBioMedicine. 2023. PMID: 36543718 Free PMC article.
The respiratory microbiome is linked to the severity of RSV infections and the persistence of symptoms in children.
Kristensen M, de Steenhuijsen Piters WAA, Wildenbeest J, van Houten MA, Zuurbier RP, Hasrat R, Arp K, Chu MLJN, Billard M, Heikkinen T, Cunningham S, Snape M, Drysdale SB, Thwaites RS, Martinon-Torres F, Pollard AJ, Openshaw PJM, Aerssen J, Binkowska J, Bont L, Bogaert D; REspiratory Syncytial virus Consortium in EUrope (RESCEU) investigators. Kristensen M, et al. Among authors: thwaites rs. Cell Rep Med. 2024 Dec 17;5(12):101836. doi: 10.1016/j.xcrm.2024.101836. Epub 2024 Dec 5. Cell Rep Med. 2024. PMID: 39642873 Free article.
Monkeypox virus isolation from longitudinal samples in 11 hospitalised patients.
Callaby H, Olver J, Emery K, Richards KS, Killip M, Groves N, Beadsworth MBJ, Price DA, Cooke GS, Collini P, Cole J, Dunning J, Semple MG, Baillie JK; ISARIC4C Investigators; Rampling T, Houlihan CF. Callaby H, et al. Lancet Infect Dis. 2025 Jan;25(1):e4-e5. doi: 10.1016/S1473-3099(24)00735-7. Epub 2024 Nov 29. Lancet Infect Dis. 2025. PMID: 39617024 No abstract available.
Incidence of diabetes mellitus following hospitalisation for COVID-19 in the United Kingdom: A prospective observational study.
Tyrer F, Gharibzadeh S, Gillies C, Lawson C, Routen A, Islam N, Razieh C, Zaccardi F, Yates T, Davies MJ, Brightling CE, Chalmers JD, Docherty AB, Elneima O, Evans RA, Greening NJ, Harris VC, Harrison EM, Ho LP, Horsley A, Houchen-Wolloff L, Leavy OC, Lone NI, Marks M, McAuley HJC, Poinasamy K, Quint JK, Raman B, Richardson M, Saunders R, Sereno M, Shikotra A, Singapuri A, Wain LV, Khunti K; PHOSP‐COVID Study Collaborative Group. Tyrer F, et al. Diabetes Obes Metab. 2024 Nov 20. doi: 10.1111/dom.16071. Online ahead of print. Diabetes Obes Metab. 2024. PMID: 39563623
Inno4Vac Workshop Report Part 1: Controlled Human Influenza Virus Infection Model (CHIVIM) Strain Selection and Immune Assays for CHIVIM Studies, November 2021, MHRA, UK.
Waldock J, Cox RJ, Chiu C, Subbarao K, Wildfire A, Barclay W, van Kasteren PB, McCauley J, Russell CA, Smith D, Thwaites RS, Tregoning JS, Engelhardt OG. Waldock J, et al. Among authors: thwaites rs. Influenza Other Respir Viruses. 2024 Nov;18(11):e70014. doi: 10.1111/irv.70014. Influenza Other Respir Viruses. 2024. PMID: 39496425 Free PMC article. Review.
Long Covid: a global health issue - a prospective, cohort study set in four continents.
Pazukhina E, Garcia-Gallo E, Reyes LF, Kildal AB, Jassat W, Dryden M, Holter JC, Chatterjee A, Gomez K, Søraas A, Puntoni M, Latronico N, Bozza FA, Edelstein M, Gonçalves BP, Kartsonaki C, Kruglova O, Gaião S, Chow YP, Doshi Y, Duque Vallejo SI, Ibáñez-Prada ED, Fuentes YV, Hastie C, O'Hara ME, Balan V, Menkir T, Merson L, Kelly S, Citarella BW, Semple MG, Scott JT, Munblit D, Sigfrid L; ISARIC Clinical Characterisation Group and ISARIC Global Covid-19 follow up working group. Pazukhina E, et al. BMJ Glob Health. 2024 Oct 21;9(10):e015245. doi: 10.1136/bmjgh-2024-015245. BMJ Glob Health. 2024. PMID: 39433402 Free PMC article.
115 results