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5-Aza-2'-deoxycytidin (Decitabine) increases cancer-testis antigen expression in head and neck squamous cell carcinoma and modifies immune checkpoint expression, especially in CD39-positive CD8 and CD4 T cells.
Fehn A, von Witzleben A, Grages A, Kors TA, Ezić J, Betzler AC, Brunner C, Schuler PJ, Theodoraki MN, Hoffmann TK, Laban S. Fehn A, et al. Among authors: ezic j. Neoplasia. 2025 Jan;59:101086. doi: 10.1016/j.neo.2024.101086. Epub 2024 Nov 27. Neoplasia. 2025. PMID: 39608124 Free PMC article.
Immune checkpoint expression on tumor-infiltrating lymphocytes (TIL) is dependent on HPV status in oropharyngeal carcinoma (OPSCC) - A single-cell RNA sequencing analysis.
von Witzleben A, Grages A, Thomas J, Ezić J, Brunner C, Schuler PJ, Kraus JM, Kestler HA, Vahl JM, Doescher J, King EV, Ottensmeier CH, Hoffmann TK, Laban S. von Witzleben A, et al. Among authors: ezic j. Oral Oncol. 2024 Dec;159:107107. doi: 10.1016/j.oraloncology.2024.107107. Epub 2024 Nov 15. Oral Oncol. 2024. PMID: 39549431 Free article.
Multi-omics analysis of overexpressed tumor-associated proteins: gene expression, immunopeptide presentation, and antibody response in oropharyngeal squamous cell carcinoma, with a focus on cancer-testis antigens.
Abou Kors T, Meier M, Mühlenbruch L, Betzler AC, Oliveri F, Bens M, Thomas J, Kraus JM, Doescher J, von Witzleben A, Hofmann L, Ezic J, Huber D, Benckendorff J, Barth TFE, Greve J, Schuler PJ, Brunner C, Blackburn JM, Hoffmann TK, Ottensmeier C, Kestler HA, Rammensee HG, Walz JS, Laban S. Abou Kors T, et al. Among authors: ezic j. Front Immunol. 2024 Jul 29;15:1408173. doi: 10.3389/fimmu.2024.1408173. eCollection 2024. Front Immunol. 2024. PMID: 39136024 Free PMC article.
INHBA is Enriched in HPV-negative Oropharyngeal Squamous Cell Carcinoma and Promotes Cancer Progression.
Abou Kors T, Hofmann L, Betzler A, Payer K, Bens M, Truong J, von Witzleben A, Thomas J, Kraus JM, Kalaajieh R, Huber D, Ezić J, Benckendorff J, Greve J, Schuler PJ, Ottensmeier CH, Kestler HA, Hoffmann TK, Theodoraki MN, Brunner C, Laban S. Abou Kors T, et al. Among authors: ezic j. Cancer Res Commun. 2024 Feb 28;4(2):571-587. doi: 10.1158/2767-9764.CRC-23-0258. Cancer Res Commun. 2024. PMID: 38329386 Free PMC article.
Influence of Bruton's Tyrosine Kinase (BTK) on Epithelial-Mesenchymal Transition (EMT) Processes and Cancer Stem Cell (CSC) Enrichment in Head and Neck Squamous Cell Carcinoma (HNSCC).
Leichtle F, Betzler AC, Eizenberger C, Lesakova K, Ezić J, Drees R, Greve J, Schuler PJ, Laban S, Hoffmann TK, Cordes N, Lavitrano M, Grassilli E, Brunner C. Leichtle F, et al. Among authors: ezic j. Int J Mol Sci. 2023 Aug 23;24(17):13133. doi: 10.3390/ijms241713133. Int J Mol Sci. 2023. PMID: 37685940 Free PMC article.
Liquid biopsy: an examination of platelet RNA obtained from head and neck squamous cell carcinoma patients for predictive molecular tumor markers.
Huber LT, Kraus JM, Ezić J, Wanli A, Groth M, Laban S, Hoffmann TK, Wollenberg B, Kestler HA, Brunner C. Huber LT, et al. Among authors: ezic j. Explor Target Antitumor Ther. 2023;4(3):422-446. doi: 10.37349/etat.2023.00143. Epub 2023 Jun 30. Explor Target Antitumor Ther. 2023. PMID: 37455825 Free PMC article.
The HLA ligandome of oropharyngeal squamous cell carcinomas reveals shared tumour-exclusive peptides for semi-personalised vaccination.
Mühlenbruch L, Abou-Kors T, Dubbelaar ML, Bichmann L, Kohlbacher O, Bens M, Thomas J, Ezić J, Kraus JM, Kestler HA, von Witzleben A, Mytilineos J, Fürst D, Engelhardt D, Doescher J, Greve J, Schuler PJ, Theodoraki MN, Brunner C, Hoffmann TK, Rammensee HG, Walz JS, Laban S. Mühlenbruch L, et al. Among authors: ezic j. Br J Cancer. 2023 May;128(9):1777-1787. doi: 10.1038/s41416-023-02197-y. Epub 2023 Feb 23. Br J Cancer. 2023. PMID: 36823366 Free PMC article.
BTK Isoforms p80 and p65 Are Expressed in Head and Neck Squamous Cell Carcinoma (HNSCC) and Involved in Tumor Progression.
Betzler AC, Strobel H, Abou Kors T, Ezić J, Lesakova K, Pscheid R, Azoitei N, Sporleder J, Staufenberg AR, Drees R, Weissinger SE, Greve J, Doescher J, Theodoraki MN, Schuler PJ, Laban S, Kibe T, Kishida M, Kishida S, Idel C, Hoffmann TK, Lavitrano M, Grassilli E, Brunner C. Betzler AC, et al. Among authors: ezic j. Cancers (Basel). 2023 Jan 3;15(1):310. doi: 10.3390/cancers15010310. Cancers (Basel). 2023. PMID: 36612306 Free PMC article.
16 results