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Mass Balance and Absorption, Distribution, Metabolism, and Excretion Properties of Balcinrenone following Oral Administration in Combination with Intravenous Microtracer in Healthy Subjects.
Lindmark B, Li XQ, Bhattacharya C, Housler G, Heijer M, Bragg RA, Gränfors M, Pelay-Gimeno M, Vaes WHJ, Menakuru S, Pizzato PE, Ericsson H, Johansson S. Lindmark B, et al. Drug Metab Dispos. 2023 Aug;51(8):995-1004. doi: 10.1124/dmd.122.001240. Epub 2023 Jul 5. Drug Metab Dispos. 2023. PMID: 37407094
Application of Accelerator Mass Spectrometry to Characterize the Mass Balance Recovery and Disposition of AZD4831, a Novel Myeloperoxidase Inhibitor, following Administration of an Oral Radiolabeled Microtracer Dose in Humans.
Bhattacharya C, Sandinge AS, Bragg RA, Heijer M, Yan J, Andersson LC, Jurva U, Pelay-Gimeno M, Vaes WHJ, de Ligt RAF, Gränfors M, Amilon C, Lindstedt EL, Menakuru SR, Garkaviy P, Weidolf L, Gopaul VS. Bhattacharya C, et al. Drug Metab Dispos. 2023 Apr;51(4):451-463. doi: 10.1124/dmd.122.001100. Epub 2023 Jan 13. Drug Metab Dispos. 2023. PMID: 36639243