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Clinical and genomic diversity of Treponema pallidum subsp. pallidum: A global, multi-center study of early syphilis to inform vaccine research.
Seña AC, Matoga MM, Yang L, Lopez-Medina E, Aghakanian F, Chen JS, Bettin EB, Caimano MJ, Chen W, Garcia-Luna JA, Hennelly CM, Jiang Y, Juliano JJ, Pospíšilová P, Ramirez L, Šmajs D, Tucker JD, Cely FV, Zheng H, Hoffman IF, Yang B, Moody MA, Hawley KL, Salazar JC, Radolf JD, Parr JB. Seña AC, et al. Among authors: radolf jd. medRxiv [Preprint]. 2023 Jul 24:2023.07.19.23291250. doi: 10.1101/2023.07.19.23291250. medRxiv. 2023. Update in: Lancet Microbe. 2024 Sep;5(9):100871. doi: 10.1016/S2666-5247(24)00087-9 PMID: 37546832 Free PMC article. Updated. Preprint.
Use of Epivolve phage display to generate a monoclonal antibody with opsonic activity directed against a subdominant epitope on extracellular loop 4 of Treponema pallidum BamA (TP0326).
Ferguson MR, Delgado KN, McBride S, Orbe IC, La Vake CJ, Caimano MJ, Mendez Q, Moraes TF, Schryvers AB, Moody MA, Radolf JD, Weiner MP, Hawley KL. Ferguson MR, et al. Among authors: radolf jd. Front Immunol. 2023 Aug 22;14:1222267. doi: 10.3389/fimmu.2023.1222267. eCollection 2023. Front Immunol. 2023. PMID: 37675118 Free PMC article.
Early syphilis in Guangzhou, China: presentation, molecular detection of Treponema pallidum , and genomic sequences in clinical specimens and isolates obtained by rabbit infectivity testing.
Yang L, Zhang X, Chen W, Seña AC, Zheng H, Jiang Y, Zhao P, Chen R, Wang L, Ke W, Salazar JC, Parr JB, Tucker JD, Hawley KL, Caimano MJ, Hennelly CM, Aghakanian F, Zhang F, Chen JS, Moody MA, Radolf JD, Yang B. Yang L, et al. Among authors: radolf jd. medRxiv [Preprint]. 2023 Oct 19:2023.10.17.23297169. doi: 10.1101/2023.10.17.23297169. medRxiv. 2023. PMID: 37905017 Free PMC article. Preprint.
Clinical Presentation of Early Syphilis and Genomic Sequences of Treponema pallidum Strains in Patient Specimens and Isolates Obtained by Rabbit Inoculation.
Yang L, Zhang X, Chen W, Seña AC, Zheng H, Jiang Y, Zhao P, Chen R, Wang L, Ke W, Salazar JC, Parr JB, Tucker JD, Hawley KL, Caimano MJ, Hennelly CM, Aghakanian F, Bettin EB, Zhang F, Chen JS, Moody MA, Radolf JD, Yang B. Yang L, et al. Among authors: radolf jd. J Infect Dis. 2024 Dec 16;230(6):e1322-e1333. doi: 10.1093/infdis/jiae322. J Infect Dis. 2024. PMID: 38884588 Free PMC article.
Treponema pallidum genetic diversity and its implications for targeted vaccine development: A cross-sectional study of early syphilis cases in Southwestern Colombia.
Salazar JC, Vargas-Cely F, García-Luna JA, Ramirez LG, Bettin EB, Romero-Rosas N, Amórtegui MF, Silva S, Oviedo O, Vigil J, La Vake CJ, Galindo X, Ramirez JD, Martínez-Valencia AJ, Caimano MJ, Hennelly CM, Aghakhanian F, Moody MA, Seña AC, Parr JB, Hawley KL, López-Medina E, Radolf JD. Salazar JC, et al. Among authors: radolf jd. PLoS One. 2024 Jul 19;19(7):e0307600. doi: 10.1371/journal.pone.0307600. eCollection 2024. PLoS One. 2024. PMID: 39028747 Free PMC article.
New Pathways in Syphilis Vaccine Development.
Liu A, Giacani L, Hawley KL, Cameron CE, Seña AC, Konda KA, Radolf JD, Klausner JD. Liu A, et al. Among authors: radolf jd. Sex Transm Dis. 2024 Nov 1;51(11):e49-e53. doi: 10.1097/OLQ.0000000000002050. Epub 2024 Jul 22. Sex Transm Dis. 2024. PMID: 39037061
Clinical and genomic diversity of Treponema pallidum subspecies pallidum to inform vaccine research: an international, molecular epidemiology study.
Seña AC, Matoga MM, Yang L, Lopez-Medina E, Aghakhanian F, Chen JS, Bettin EB, Caimano MJ, Chen W, Garcia-Luna JA, Hennelly CM, Jere E, Jiang Y, Juliano JJ, Pospíšilová P, Ramirez L, Šmajs D, Tucker JD, Vargas Cely F, Zheng H, Hoffman IF, Yang B, Moody MA, Hawley KL, Salazar JC, Radolf JD, Parr JB. Seña AC, et al. Among authors: radolf jd. Lancet Microbe. 2024 Sep;5(9):100871. doi: 10.1016/S2666-5247(24)00087-9. Epub 2024 Aug 22. Lancet Microbe. 2024. PMID: 39181152 Free PMC article.
Development and utilization of Treponema pallidum expressing green fluorescent protein to study spirochete-host interactions and antibody-mediated clearance: expanding the toolbox for syphilis research.
Delgado KN, Vicente CF, Hennelly CM, Aghakhanian F, Parr JB, Claffey KP, Radolf JD, Hawley KL, Caimano MJ. Delgado KN, et al. Among authors: radolf jd. bioRxiv [Preprint]. 2024 Oct 21:2024.10.21.619476. doi: 10.1101/2024.10.21.619476. bioRxiv. 2024. Update in: mBio. 2024 Nov 29:e0325324. doi: 10.1128/mbio.03253-24 PMID: 39484466 Free PMC article. Updated. Preprint.
236 results