Brown RDR - Search Results

1

FTY720/Fingolimod mitigates paclitaxel-induced Sparcl1-driven neuropathic pain and breast cancer progression.

Singh SK, Weigel C, Brown RDR, Green CD, Tuck C, Salvemini D, Spiegel S. Singh SK, et al. Among authors: brown rdr. FASEB J. 2024 Aug 15;38(15):e23872. doi: 10.1096/fj.202401277R. FASEB J. 2024. PMID: 39126272 Free PMC article.

2

A new preclinical model of western diet-induced progression of non-alcoholic steatohepatitis to hepatocellular carcinoma.

Green CD, Weigel C, Brown RDR, Bedossa P, Dozmorov M, Sanyal AJ, Spiegel S. Green CD, et al. Among authors: brown rdr. FASEB J. 2022 Jul;36(7):e22372. doi: 10.1096/fj.202200346R. FASEB J. 2022. PMID: 35639028 Free PMC article.

3

Neutrophilia in severe asthma is reduced in Ormdl3 overexpressing mice.

James BN, Weigel C, Green CD, Brown RDR, Palladino END, Tharakan A, Milstien S, Proia RL, Martin RK, Spiegel S. James BN, et al. Among authors: brown rdr. FASEB J. 2023 Mar;37(3):e22799. doi: 10.1096/fj.202201821R. FASEB J. 2023. PMID: 36753412 Free PMC article.

4

Overexpression of ORMDL3 confers sexual dimorphism in diet-induced non-alcoholic steatohepatitis.

Brown RDR, Green CD, Weigel C, Ni B, Celi FS, Proia RL, Spiegel S. Brown RDR, et al. Mol Metab. 2024 Jan;79:101851. doi: 10.1016/j.molmet.2023.101851. Epub 2023 Dec 9. Mol Metab. 2024. PMID: 38081412 Free PMC article.

5

Sphingosine kinase 2 and p62 regulation are determinants of sexual dimorphism in hepatocellular carcinoma.

Green CD, Brown RDR, Uranbileg B, Weigel C, Saha S, Kurano M, Yatomi Y, Spiegel S. Green CD, et al. Among authors: brown rdr. Mol Metab. 2024 Aug;86:101971. doi: 10.1016/j.molmet.2024.101971. Epub 2024 Jun 24. Mol Metab. 2024. PMID: 38925249 Free PMC article.

6

ORMDL in metabolic health and disease.

Brown RDR, Spiegel S. Brown RDR, et al. Pharmacol Ther. 2023 May;245:108401. doi: 10.1016/j.pharmthera.2023.108401. Epub 2023 Mar 30. Pharmacol Ther. 2023. PMID: 37003301 Free PMC article. Review.

7

ORMDL mislocalization by impaired autophagy in Niemann-Pick type C disease leads to increased de novo sphingolipid biosynthesis.

Brown RDR, Mahawar U, Wattenberg BW, Spiegel S. Brown RDR, et al. J Lipid Res. 2024 Jun;65(6):100556. doi: 10.1016/j.jlr.2024.100556. Epub 2024 May 6. J Lipid Res. 2024. PMID: 38719150 Free PMC article.

8

The sterol transporter STARD3 transports sphingosine at ER-lysosome contact sites.

Hempelmann P, Lolicato F, Graziadei A, Brown RDR, Spiegel S, Rappsilber J, Nickel W, Höglinger D, Jamecna D. Hempelmann P, et al. Among authors: brown rdr. bioRxiv [Preprint]. 2023 Sep 18:2023.09.18.557036. doi: 10.1101/2023.09.18.557036. bioRxiv. 2023. PMID: 37790546 Free PMC article. Preprint.

9

Dihydroceramide Desaturase Functions as an Inducer and Rectifier of Apoptosis: Effect of Retinol Derivatives, Antioxidants and Phenolic Compounds.

Alsanafi M, Brown RDR, Oh J, Adams DR, Torta F, Pyne NJ, Pyne S. Alsanafi M, et al. Among authors: brown rdr. Cell Biochem Biophys. 2021 Sep;79(3):461-475. doi: 10.1007/s12013-021-00990-1. Epub 2021 May 15. Cell Biochem Biophys. 2021. PMID: 33991313 Free PMC article.

10

A new model for regulation of sphingosine kinase 1 translocation to the plasma membrane in breast cancer cells.

Brown RDR, Veerman BEP, Oh J, Tate RJ, Torta F, Cunningham MR, Adams DR, Pyne S, Pyne NJ. Brown RDR, et al. J Biol Chem. 2021 Jan-Jun;296:100674. doi: 10.1016/j.jbc.2021.100674. Epub 2021 Apr 16. J Biol Chem. 2021. PMID: 33865856 Free PMC article.

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