Hu X - Search Results

1

Deciphering the interaction between PKM2 and the built-in thermodynamic properties of the glycolytic pathway in cancer cells.

Jin C, Hu W, Wang Y, Wu H, Zeng S, Ying M, Hu X. Jin C, et al. Among authors: hu x, hu w. J Biol Chem. 2024 Sep;300(9):107648. doi: 10.1016/j.jbc.2024.107648. Epub 2024 Aug 8. J Biol Chem. 2024. PMID: 39121998 Free PMC article.

2

Central role of lactic acidosis in cancer cell resistance to glucose deprivation-induced cell death.

Wu H, Ding Z, Hu D, Sun F, Dai C, Xie J, Hu X. Wu H, et al. Among authors: hu d, hu x. J Pathol. 2012 Jun;227(2):189-99. doi: 10.1002/path.3978. Epub 2012 Feb 17. J Pathol. 2012. PMID: 22190257

3

Anticancer agent shikonin is an incompetent inducer of cancer drug resistance.

Wu H, Xie J, Pan Q, Wang B, Hu D, Hu X. Wu H, et al. Among authors: hu d, hu x. PLoS One. 2013;8(1):e52706. doi: 10.1371/journal.pone.0052706. Epub 2013 Jan 3. PLoS One. 2013. PMID: 23300986 Free PMC article.

4

Beyond Warburg effect--dual metabolic nature of cancer cells.

Xie J, Wu H, Dai C, Pan Q, Ding Z, Hu D, Ji B, Luo Y, Hu X. Xie J, et al. Among authors: hu d, hu x. Sci Rep. 2014 May 13;4:4927. doi: 10.1038/srep04927. Sci Rep. 2014. PMID: 24820099 Free PMC article.

5

No evident dose-response relationship between cellular ROS level and its cytotoxicity--a paradoxical issue in ROS-based cancer therapy.

Zhu C, Hu W, Wu H, Hu X. Zhu C, et al. Among authors: hu x, hu w. Sci Rep. 2014 May 22;4:5029. doi: 10.1038/srep05029. Sci Rep. 2014. PMID: 24848642 Free PMC article. Clinical Trial.

6

Evidence That Does Not Support Pyruvate Kinase M2 (PKM2)-catalyzed Reaction as a Rate-limiting Step in Cancer Cell Glycolysis.

Xie J, Dai C, Hu X. Xie J, et al. Among authors: hu x. J Biol Chem. 2016 Apr 22;291(17):8987-99. doi: 10.1074/jbc.M115.704825. Epub 2016 Feb 25. J Biol Chem. 2016. PMID: 26917721 Free PMC article.

7

Lactic acidosis switches cancer cells from aerobic glycolysis back to dominant oxidative phosphorylation.

Wu H, Ying M, Hu X. Wu H, et al. Among authors: hu x. Oncotarget. 2016 Jun 28;7(26):40621-40629. doi: 10.18632/oncotarget.9746. Oncotarget. 2016. PMID: 27259254 Free PMC article.

8

A nonrandomized cohort and a randomized study of local control of large hepatocarcinoma by targeting intratumoral lactic acidosis.

Chao M, Wu H, Jin K, Li B, Wu J, Zhang G, Yang G, Hu X. Chao M, et al. Among authors: hu x. Elife. 2016 Aug 2;5:e15691. doi: 10.7554/eLife.15691. Elife. 2016. PMID: 27481188 Free PMC article. Clinical Trial.

9

Evidence of drug-response heterogeneity rapidly generated from a single cancer cell.

Wang R, Jin C, Hu X. Wang R, et al. Among authors: hu x. Oncotarget. 2017 Jun 20;8(25):41113-41124. doi: 10.18632/oncotarget.17064. Oncotarget. 2017. PMID: 28467802 Free PMC article.

10

Quantification of lactate from various metabolic pathways and quantification issues of lactate isotopologues and isotopmers.

Zhang W, Guo C, Jiang K, Ying M, Hu X. Zhang W, et al. Among authors: hu x. Sci Rep. 2017 Aug 16;7(1):8489. doi: 10.1038/s41598-017-08277-3. Sci Rep. 2017. PMID: 28814730 Free PMC article.

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