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Targeted delivery of tumor necrosis factor in combination with CCNU induces a T cell-dependent regression of glioblastoma.
Look T, Puca E, Bühler M, Kirschenbaum D, De Luca R, Stucchi R, Ravazza D, Di Nitto C, Roth P, Katzenelenbogen Y, Weiner A, Rindlisbacher L, Becher B, Amit I, Weller M, Neri D, Hemmerle T, Weiss T. Look T, et al. Sci Transl Med. 2023 May 24;15(697):eadf2281. doi: 10.1126/scitranslmed.adf2281. Epub 2023 May 24. Sci Transl Med. 2023. PMID: 37224228
Generation and in vivo validation of an IL-12 fusion protein based on a novel anti-human FAP monoclonal antibody.
Nadal L, Peissert F, Elsayed A, Weiss T, Look T, Weller M, Piro G, Carbone C, Tortora G, Matasci M, Favalli N, Corbellari R, Di Nitto C, Prodi E, Libbra C, Galeazzi S, Carotenuto C, Halin C, Puca E, Neri D, De Luca R. Nadal L, et al. Among authors: look t. J Immunother Cancer. 2022 Sep;10(9):e005282. doi: 10.1136/jitc-2022-005282. J Immunother Cancer. 2022. PMID: 36104101 Free PMC article.
An IL-7 fusion protein targeting EDA fibronectin upregulates TCF1 on CD8+ T-cells, preferentially accumulates to neoplastic lesions, and boosts PD-1 blockade.
Di Nitto C, Ravazza D, Gilardoni E, Look T, Sun M, Prodi E, Moisoiu V, Pellegrino C, Manz MG, Puca E, Weller M, Weiss T, Neri D, De Luca R. Di Nitto C, et al. Among authors: look t. J Immunother Cancer. 2024 Aug 13;12(8):e008504. doi: 10.1136/jitc-2023-008504. J Immunother Cancer. 2024. PMID: 39142716 Free PMC article.
Time-resolved single-cell transcriptomics defines immune trajectories in glioblastoma.
Kirschenbaum D, Xie K, Ingelfinger F, Katzenelenbogen Y, Abadie K, Look T, Sheban F, Phan TS, Li B, Zwicky P, Yofe I, David E, Mazuz K, Hou J, Chen Y, Shaim H, Shanley M, Becker S, Qian J, Colonna M, Ginhoux F, Rezvani K, Theis FJ, Yosef N, Weiss T, Weiner A, Amit I. Kirschenbaum D, et al. Among authors: look t. Cell. 2024 Jan 4;187(1):149-165.e23. doi: 10.1016/j.cell.2023.11.032. Epub 2023 Dec 21. Cell. 2024. PMID: 38134933 Free article.
34 results