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Page 1
Age-Specific ADME Gene Expression in Infant Intestinal Enteroids.
Streekstra EJ, Scheer-Weijers T, Bscheider M, Fuerst-Recktenwald S, Roth A, van Ijzendoorn SCD, Botden S, de Boode W, Stommel MWJ, Greupink R, Russel FGM, van de Steeg E, de Wildt SN. Streekstra EJ, et al. Among authors: van de steeg e. Mol Pharm. 2024 Sep 2;21(9):4347-4355. doi: 10.1021/acs.molpharmaceut.4c00302. Epub 2024 Aug 9. Mol Pharm. 2024. PMID: 39120063 Free PMC article.
Impact of abcc2 [multidrug resistance-associated protein (MRP) 2], abcc3 (MRP3), and abcg2 (breast cancer resistance protein) on the oral pharmacokinetics of methotrexate and its main metabolite 7-hydroxymethotrexate.
Vlaming ML, van Esch A, van de Steeg E, Pala Z, Wagenaar E, van Tellingen O, Schinkel AH. Vlaming ML, et al. Among authors: van de steeg e, van tellingen o, van esch a. Drug Metab Dispos. 2011 Aug;39(8):1338-44. doi: 10.1124/dmd.111.038794. Epub 2011 May 12. Drug Metab Dispos. 2011. PMID: 21566011
Organic anion-transporting polypeptide 1B1 mediates transport of Gimatecan and BNP1350 and can be inhibited by several classic ATP-binding cassette (ABC) B1 and/or ABCG2 inhibitors.
Oostendorp RL, van de Steeg E, van der Kruijssen CM, Beijnen JH, Kenworthy KE, Schinkel AH, Schellens JH. Oostendorp RL, et al. Among authors: van de steeg e, van der kruijssen cm. Drug Metab Dispos. 2009 Apr;37(4):917-23. doi: 10.1124/dmd.108.024901. Epub 2009 Jan 12. Drug Metab Dispos. 2009. PMID: 19139163
OATP1A/1B transporters affect irinotecan and SN-38 pharmacokinetics and carboxylesterase expression in knockout and humanized transgenic mice.
Iusuf D, Ludwig M, Elbatsh A, van Esch A, van de Steeg E, Wagenaar E, van der Valk M, Lin F, van Tellingen O, Schinkel AH. Iusuf D, et al. Among authors: van de steeg e, van tellingen o, van esch a, van der valk m. Mol Cancer Ther. 2014 Feb;13(2):492-503. doi: 10.1158/1535-7163.MCT-13-0541. Epub 2013 Nov 5. Mol Cancer Ther. 2014. PMID: 24194565
54 results