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LIM-domain-only 4 (LMO4) enhances CD8+ T-cell stemness and tumor rejection by boosting IL-21-STAT3 signaling.
Schelker RC, Fioravanti J, Mastrogiovanni F, Baldwin JG, Rana N, Li P, Chen P, Vadász T, Spolski R, Heuser-Loy C, Slavkovic-Lukic D, Noronha P, Damiano G, Raccosta L, Maggioni D, Pullugula S, Lin JX, Oh J, Grandinetti P, Lecce M, Hesse L, Kocks E, Martín-Santos A, Gebhard C, Telford WG, Ji Y, Restifo NP, Russo V, Rehli M, Herr W, Leonard WJ, Gattinoni L. Schelker RC, et al. Among authors: gebhard c. Signal Transduct Target Ther. 2024 Aug 9;9(1):199. doi: 10.1038/s41392-024-01915-z. Signal Transduct Target Ther. 2024. PMID: 39117617 Free PMC article.
C-Jun drives melanoma progression in PTEN wild type melanoma cells.
Kappelmann-Fenzl M, Gebhard C, Matthies AO, Kuphal S, Rehli M, Bosserhoff AK. Kappelmann-Fenzl M, et al. Among authors: gebhard c. Cell Death Dis. 2019 Aug 5;10(8):584. doi: 10.1038/s41419-019-1821-9. Cell Death Dis. 2019. PMID: 31378787 Free PMC article.
Physiological levels of 25-hydroxyvitamin D3 induce a suppressive CD4+ T cell phenotype not reflected in the epigenetic landscape.
Matos C, Renner K, Peuker A, Schoenhammer G, Schreiber L, Bruss C, Eder R, Bruns H, Flamann C, Hoffmann P, Gebhard C, Herr W, Rehli M, Peter K, Kreutz M. Matos C, et al. Among authors: gebhard c. Scand J Immunol. 2022 May;95(5):e13146. doi: 10.1111/sji.13146. Epub 2022 Feb 1. Scand J Immunol. 2022. PMID: 35073416 Free article.
Salt-inducible kinase 3 protects tumor cells from cytotoxic T-cell attack by promoting TNF-induced NF-κB activation.
Sorrentino A, Menevse AN, Michels T, Volpin V, Durst FC, Sax J, Xydia M, Hussein A, Stamova S, Spoerl S, Heuschneider N, Muehlbauer J, Jeltsch KM, Rathinasamy A, Werner-Klein M, Breinig M, Mikietyn D, Kohler C, Poschke I, Purr S, Reidell O, Martins Freire C, Offringa R, Gebhard C, Spang R, Rehli M, Boutros M, Schmidl C, Khandelwal N, Beckhove P. Sorrentino A, et al. Among authors: gebhard c. J Immunother Cancer. 2022 May;10(5):e004258. doi: 10.1136/jitc-2021-004258. J Immunother Cancer. 2022. PMID: 35606086 Free PMC article.
Biosensors for inflammation as a strategy to engineer regulatory T cells for cell therapy.
Bittner S, Ruhland B, Hofmann V, Schmidleithner L, Schambeck K, Pant A, Stüve P, Delacher M, Echtenacher B, Edinger M, Hoffmann P, Rehli M, Gebhard C, Strieder N, Hehlgans T, Feuerer M. Bittner S, et al. Among authors: gebhard c. Proc Natl Acad Sci U S A. 2022 Oct 4;119(40):e2208436119. doi: 10.1073/pnas.2208436119. Epub 2022 Sep 26. Proc Natl Acad Sci U S A. 2022. PMID: 36161919 Free PMC article.
278 results