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Page 1
Computational Design of Pore-Forming Peptides with Potent Antimicrobial and Anticancer Activities.
Deb R, Torres MDT, Boudný M, Koběrská M, Cappiello F, Popper M, Dvořáková Bendová K, Drabinová M, Hanáčková A, Jeannot K, Petřík M, Mangoni ML, Balíková Novotná G, Mráz M, de la Fuente-Nunez C, Vácha R. Deb R, et al. Among authors: boudny m. J Med Chem. 2024 Aug 22;67(16):14040-14061. doi: 10.1021/acs.jmedchem.4c00912. Epub 2024 Aug 8. J Med Chem. 2024. PMID: 39116273 Free PMC article.
Stromal cells engineered to express T cell factors induce robust CLL cell proliferation in vitro and in PDX co-transplantations allowing the identification of RAF inhibitors as anti-proliferative drugs.
Hoferkova E, Seda V, Kadakova S, Verner J, Loja T, Matulova K, Skuhrova Francova H, Ondrouskova E, Filip D, Blavet N, Boudny M, Mladonicka Pavlasova G, Vecera J, Ondrisova L, Pavelkova P, Hlavac K, Kostalova L, Michaelou A, Pospisilova S, Dorazilova J, Chochola V, Jaros J, Doubek M, Jarosova M, Hampl A, Vojtova L, Kren L, Mayer J, Mraz M. Hoferkova E, et al. Among authors: boudny m. Leukemia. 2024 Aug;38(8):1699-1711. doi: 10.1038/s41375-024-02284-w. Epub 2024 Jun 14. Leukemia. 2024. PMID: 38877102 Free PMC article.
Novel CHK1 inhibitor MU380 exhibits significant single-agent activity in TP53-mutated chronic lymphocytic leukemia cells.
Boudny M, Zemanova J, Khirsariya P, Borsky M, Verner J, Cerna J, Oltova A, Seda V, Mraz M, Jaros J, Jaskova Z, Spunarova M, Brychtova Y, Soucek K, Drapela S, Kasparkova M, Mayer J, Paruch K, Trbusek M. Boudny M, et al. Haematologica. 2019 Dec;104(12):2443-2455. doi: 10.3324/haematol.2018.203430. Epub 2019 Apr 11. Haematologica. 2019. PMID: 30975914 Free PMC article.