Ortmayer M - Search Results

1

Probing Ferryl Reactivity in a Nonheme Iron Oxygenase Using an Expanded Genetic Code.

Hardy FJ, Quesne MG, Gérard EF, Zhao J, Ortmayer M, Taylor CJ, Ali HS, Slater JW, Levy CW, Heyes DJ, Bollinger JM Jr, de Visser SP, Green AP. Hardy FJ, et al. Among authors: ortmayer m. ACS Catal. 2024 Jul 20;14(15):11584-11590. doi: 10.1021/acscatal.4c02365. eCollection 2024 Aug 2. ACS Catal. 2024. PMID: 39114090 Free PMC article.

2

Rewiring the "Push-Pull" Catalytic Machinery of a Heme Enzyme Using an Expanded Genetic Code.

Ortmayer M, Fisher K, Basran J, Wolde-Michael EM, Heyes DJ, Levy C, Lovelock SL, Anderson JLR, Raven EL, Hay S, Rigby SEJ, Green AP. Ortmayer M, et al. ACS Catal. 2020 Feb 21;10(4):2735-2746. doi: 10.1021/acscatal.9b05129. Epub 2020 Jan 29. ACS Catal. 2020. PMID: 32550044 Free PMC article.

3

A Noncanonical Tryptophan Analogue Reveals an Active Site Hydrogen Bond Controlling Ferryl Reactivity in a Heme Peroxidase.

Ortmayer M, Hardy FJ, Quesne MG, Fisher K, Levy C, Heyes DJ, Catlow CRA, de Visser SP, Rigby SEJ, Hay S, Green AP. Ortmayer M, et al. JACS Au. 2021 Jul 26;1(7):913-918. doi: 10.1021/jacsau.1c00145. Epub 2021 May 14. JACS Au. 2021. PMID: 34337604 Free PMC article.

4

Engineering enzyme activity using an expanded amino acid alphabet.

Birch-Price Z, Taylor CJ, Ortmayer M, Green AP. Birch-Price Z, et al. Among authors: ortmayer m. Protein Eng Des Sel. 2023 Jan 21;36:gzac013. doi: 10.1093/protein/gzac013. Protein Eng Des Sel. 2023. PMID: 36370045 Free PMC article.

5

Design of Heme Enzymes with a Tunable Substrate Binding Pocket Adjacent to an Open Metal Coordination Site.

Kalvet I, Ortmayer M, Zhao J, Crawshaw R, Ennist NM, Levy C, Roy A, Green AP, Baker D. Kalvet I, et al. Among authors: ortmayer m. J Am Chem Soc. 2023 Jul 5;145(26):14307-14315. doi: 10.1021/jacs.3c02742. Epub 2023 Jun 21. J Am Chem Soc. 2023. PMID: 37341421 Free PMC article.

6

Design and evolution of an enzyme with a non-canonical organocatalytic mechanism.

Burke AJ, Lovelock SL, Frese A, Crawshaw R, Ortmayer M, Dunstan M, Levy C, Green AP. Burke AJ, et al. Among authors: ortmayer m. Nature. 2019 Jun;570(7760):219-223. doi: 10.1038/s41586-019-1262-8. Epub 2019 May 27. Nature. 2019. PMID: 31132786

7

An oxidative N-demethylase reveals PAS transition from ubiquitous sensor to enzyme.

Ortmayer M, Lafite P, Menon BR, Tralau T, Fisher K, Denkhaus L, Scrutton NS, Rigby SE, Munro AW, Hay S, Leys D. Ortmayer M, et al. Nature. 2016 Nov 24;539(7630):593-597. doi: 10.1038/nature20159. Epub 2016 Nov 16. Nature. 2016. PMID: 27851736

8

Identification of a Class of Protein ADP-Ribosylating Sirtuins in Microbial Pathogens.

Rack JG, Morra R, Barkauskaite E, Kraehenbuehl R, Ariza A, Qu Y, Ortmayer M, Leidecker O, Cameron DR, Matic I, Peleg AY, Leys D, Traven A, Ahel I. Rack JG, et al. Among authors: ortmayer m. Mol Cell. 2015 Jul 16;59(2):309-20. doi: 10.1016/j.molcel.2015.06.013. Epub 2015 Jul 9. Mol Cell. 2015. PMID: 26166706 Free PMC article.

9

Some early reminiscences.

Ortmayer M. Ortmayer M. Gastrointest Endosc. 1970 May;16(4):201. Gastrointest Endosc. 1970. PMID: 5426587 No abstract available.

10

Chronic peptic ulcer in children.

ORTMAYER M. ORTMAYER M. J Am Med Womens Assoc. 1957 Apr;12(4):95-8. J Am Med Womens Assoc. 1957. PMID: 13416019 No abstract available.

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