Ratcliffe PJ - Search Results

1

Hif-2α programs oxygen chemosensitivity in chromaffin cells.

Prange-Barczynska M, Jones HA, Sugimoto Y, Cheng X, Lima JD, Ratnayaka I, Douglas G, Buckler KJ, Ratcliffe PJ, Keeley TP, Bishop T. Prange-Barczynska M, et al. Among authors: ratcliffe pj. J Clin Invest. 2024 Aug 6;134(18):e174661. doi: 10.1172/JCI174661. J Clin Invest. 2024. PMID: 39106106 Free PMC article.

2

Comparative analysis of N-terminal cysteine dioxygenation and prolyl-hydroxylation as oxygen-sensing pathways in mammalian cells.

Tian YM, Holdship P, To TQ, Ratcliffe PJ, Keeley TP. Tian YM, et al. Among authors: ratcliffe pj. J Biol Chem. 2023 Sep;299(9):105156. doi: 10.1016/j.jbc.2023.105156. Epub 2023 Aug 10. J Biol Chem. 2023. PMID: 37572852 Free PMC article.

3

[No title available]

[No authors listed] [No authors listed] PMID: 38589097

4

N-terminal cysteine acetylation and oxidation patterns may define protein stability.

Heathcote KC, Keeley TP, Myllykoski M, Lundekvam M, McTiernan N, Akter S, Masson N, Ratcliffe PJ, Arnesen T, Flashman E. Heathcote KC, et al. Among authors: ratcliffe pj. Nat Commun. 2024 Jun 25;15(1):5360. doi: 10.1038/s41467-024-49489-2. Nat Commun. 2024. PMID: 38918375 Free PMC article.

5

Oncogenic Cell Tagging and Single-Cell Transcriptomics Reveal Cell Type-Specific and Time-Resolved Responses to Vhl Inactivation in the Kidney.

Kurlekar S, Lima JDCC, Li R, Lombardi O, Masson N, Barros AB, Pontecorvi V, Mole DR, Pugh CW, Adam J, Ratcliffe PJ. Kurlekar S, et al. Among authors: ratcliffe pj. Cancer Res. 2024 Jun 4;84(11):1799-1816. doi: 10.1158/0008-5472.CAN-23-3248. Cancer Res. 2024. PMID: 38502859 Free PMC article.

6

Deficiency of factor-inhibiting HIF creates a tumor-promoting immune microenvironment.

Ma J, Al Moussawi K, Lou H, Chan HF, Wang Y, Chadwick J, Phetsouphanh C, Slee EA, Zhong S, Leissing TM, Roth A, Qin X, Chen S, Yin J, Ratnayaka I, Hu Y, Louphrasitthiphol P, Taylor L, Bettencourt PJG, Muers M, Greaves DR, McShane H, Goldin R, Soilleux EJ, Coleman ML, Ratcliffe PJ, Lu X. Ma J, et al. Among authors: ratcliffe pj. Proc Natl Acad Sci U S A. 2024 Mar 5;121(10):e2309957121. doi: 10.1073/pnas.2309957121. Epub 2024 Feb 29. Proc Natl Acad Sci U S A. 2024. PMID: 38422022 Free PMC article.

7

Multi-level interaction between HIF and AHR transcriptional pathways in kidney carcinoma.

Lafleur VN, Halim S, Choudhry H, Ratcliffe PJ, Mole DR. Lafleur VN, et al. Among authors: ratcliffe pj. Life Sci Alliance. 2023 Feb 1;6(4):e202201756. doi: 10.26508/lsa.202201756. Print 2023 Apr. Life Sci Alliance. 2023. PMID: 36725335 Free PMC article.

8

Pan-cancer analysis of tissue and single-cell HIF-pathway activation using a conserved gene signature.

Lombardi O, Li R, Halim S, Choudhry H, Ratcliffe PJ, Mole DR. Lombardi O, et al. Among authors: ratcliffe pj. Cell Rep. 2022 Nov 15;41(7):111652. doi: 10.1016/j.celrep.2022.111652. Cell Rep. 2022. PMID: 36384128 Free PMC article.

9

A global view of the aspiring physician-scientist.

Williams CS, Rathmell WK, Carethers JM, Harper DM, Lo YMD, Ratcliffe PJ, Zaidi M. Williams CS, et al. Among authors: ratcliffe pj. Elife. 2022 Sep 13;11:e79738. doi: 10.7554/eLife.79738. Elife. 2022. PMID: 36098684 Free PMC article. Review.

10

Isoform-resolved mRNA profiling of ribosome load defines interplay of HIF and mTOR dysregulation in kidney cancer.

Sugimoto Y, Ratcliffe PJ. Sugimoto Y, et al. Among authors: ratcliffe pj. Nat Struct Mol Biol. 2022 Sep;29(9):871-880. doi: 10.1038/s41594-022-00819-2. Epub 2022 Sep 12. Nat Struct Mol Biol. 2022. PMID: 36097292 Free PMC article.

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