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Page 1
Oligodendrocytes produce amyloid-β and contribute to plaque formation alongside neurons in Alzheimer's disease model mice.
Sasmita AO, Depp C, Nazarenko T, Sun T, Siems SB, Ong EC, Nkeh YB, Böhler C, Yu X, Bues B, Evangelista L, Mao S, Morgado B, Wu Z, Ruhwedel T, Subramanian S, Börensen F, Overhoff K, Spieth L, Berghoff SA, Sadleir KR, Vassar R, Eggert S, Goebbels S, Saito T, Saido T, Saher G, Möbius W, Castelo-Branco G, Klafki HW, Wirths O, Wiltfang J, Jäkel S, Yan R, Nave KA. Sasmita AO, et al. Among authors: siems sb. Nat Neurosci. 2024 Sep;27(9):1668-1674. doi: 10.1038/s41593-024-01730-3. Epub 2024 Aug 5. Nat Neurosci. 2024. PMID: 39103558 Free PMC article.
Progressive axonopathy when oligodendrocytes lack the myelin protein CMTM5.
Buscham TJ, Eichel-Vogel MA, Steyer AM, Jahn O, Strenzke N, Dardawal R, Memhave TR, Siems SB, Müller C, Meschkat M, Sun T, Ruhwedel T, Möbius W, Krämer-Albers EM, Boretius S, Nave KA, Werner HB. Buscham TJ, et al. Among authors: siems sb. Elife. 2022 Mar 11;11:e75523. doi: 10.7554/eLife.75523. Elife. 2022. PMID: 35274615 Free PMC article.
Proteome Profile of Myelin in the Zebrafish Brain.
Siems SB, Jahn O, Hoodless LJ, Jung RB, Hesse D, Möbius W, Czopka T, Werner HB. Siems SB, et al. Front Cell Dev Biol. 2021 Apr 8;9:640169. doi: 10.3389/fcell.2021.640169. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 33898427 Free PMC article.
Turning to myelin turnover.
Buscham TJ, Eichel MA, Siems SB, Werner HB. Buscham TJ, et al. Among authors: siems sb. Neural Regen Res. 2019 Dec;14(12):2063-2066. doi: 10.4103/1673-5374.262569. Neural Regen Res. 2019. PMID: 31397333 Free PMC article. Review.