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An improved SNAP-ADAR tool enables efficient RNA base editing to interfere with post-translational protein modification.
Nat Commun. 2024 Aug 5;15(1):6615. doi: 10.1038/s41467-024-50395-w.
Nat Commun. 2024.
PMID: 39103360
Free PMC article.
Precise in vivo RNA base editing with a wobble-enhanced circular CLUSTER guide RNA.
Reautschnig P, Fruhner C, Wahn N, Wiegand CP, Kragness S, Yung JF, Hofacker DT, Fisk J, Eidelman M, Waffenschmidt N, Feige M, Pfeiffer LS, Schulz AE, Füll Y, Levanon EY, Mandel G, Stafforst T.
Reautschnig P, et al.
Nat Biotechnol. 2024 Jul 12. doi: 10.1038/s41587-024-02313-0. Online ahead of print.
Nat Biotechnol. 2024.
PMID: 38997581
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CLUSTER guide RNAs enable precise and efficient RNA editing with endogenous ADAR enzymes in vivo.
Reautschnig P, Wahn N, Wettengel J, Schulz AE, Latifi N, Vogel P, Kang TW, Pfeiffer LS, Zarges C, Naumann U, Zender L, Li JB, Stafforst T.
Reautschnig P, et al.
Nat Biotechnol. 2022 May;40(5):759-768. doi: 10.1038/s41587-021-01105-0. Epub 2022 Jan 3.
Nat Biotechnol. 2022.
PMID: 34980913
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Precise RNA editing by recruiting endogenous ADARs with antisense oligonucleotides.
Merkle T, Merz S, Reautschnig P, Blaha A, Li Q, Vogel P, Wettengel J, Li JB, Stafforst T.
Merkle T, et al. Among authors: reautschnig p.
Nat Biotechnol. 2019 Feb;37(2):133-138. doi: 10.1038/s41587-019-0013-6. Epub 2019 Jan 28.
Nat Biotechnol. 2019.
PMID: 30692694
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Applying Human ADAR1p110 and ADAR1p150 for Site-Directed RNA Editing-G/C Substitution Stabilizes GuideRNAs against Editing.
Heep M, Mach P, Reautschnig P, Wettengel J, Stafforst T.
Heep M, et al. Among authors: reautschnig p.
Genes (Basel). 2017 Jan 14;8(1):34. doi: 10.3390/genes8010034.
Genes (Basel). 2017.
PMID: 28098820
Free PMC article.
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Harnessing human ADAR2 for RNA repair - Recoding a PINK1 mutation rescues mitophagy.
Wettengel J, Reautschnig P, Geisler S, Kahle PJ, Stafforst T.
Wettengel J, et al. Among authors: reautschnig p.
Nucleic Acids Res. 2017 Mar 17;45(5):2797-2808. doi: 10.1093/nar/gkw911.
Nucleic Acids Res. 2017.
PMID: 27907896
Free PMC article.
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The notorious R.N.A. in the spotlight - drug or target for the treatment of disease.
Reautschnig P, Vogel P, Stafforst T.
Reautschnig P, et al.
RNA Biol. 2017 May 4;14(5):651-668. doi: 10.1080/15476286.2016.1208323. Epub 2016 Jul 14.
RNA Biol. 2017.
PMID: 27415589
Free PMC article.
Review.
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In vivo genome editing using nuclease-encoding mRNA corrects SP-B deficiency.
Mahiny AJ, Dewerth A, Mays LE, Alkhaled M, Mothes B, Malaeksefat E, Loretz B, Rottenberger J, Brosch DM, Reautschnig P, Surapolchai P, Zeyer F, Schams A, Carevic M, Bakele M, Griese M, Schwab M, Nürnberg B, Beer-Hammer S, Handgretinger R, Hartl D, Lehr CM, Kormann MS.
Mahiny AJ, et al. Among authors: reautschnig p.
Nat Biotechnol. 2015 Jun;33(6):584-6. doi: 10.1038/nbt.3241. Epub 2015 May 18.
Nat Biotechnol. 2015.
PMID: 25985262
No abstract available.
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