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A neurodevelopmental disorder mutation locks G proteins in the transitory pre-activated state.
Knight KM, Krumm BE, Kapolka NJ, Ludlam WG, Cui M, Mani S, Prytkova I, Obarow EG, Lefevre TJ, Wei W, Ma N, Huang XP, Fay JF, Vaidehi N, Smrcka AV, Slesinger PA, Logothetis DE, Martemyanov KA, Roth BL, Dohlman HG. Knight KM, et al. Among authors: obarow eg. Nat Commun. 2024 Aug 5;15(1):6643. doi: 10.1038/s41467-024-50964-z. Nat Commun. 2024. PMID: 39103320 Free PMC article.
Molecular annotation of G protein variants in a neurological disorder.
Knight KM, Obarow EG, Wei W, Mani S, Esteller MI, Cui M, Ma N, Martin SA, Brinson E, Hewitt N, Soden GM, Logothetis DE, Vaidehi N, Dohlman HG. Knight KM, et al. Among authors: obarow eg. Cell Rep. 2023 Dec 26;42(12):113578. doi: 10.1016/j.celrep.2023.113578. Epub 2023 Dec 2. Cell Rep. 2023. PMID: 38043061 Free PMC article. No abstract available.
Molecular annotation of G protein variants in a neurological disorder.
Knight KM, Obarow EG, Wei W, Mani S, Esteller MI, Cui M, Ma N, Martin SA, Brinson E, Hewitt N, Soden GM, Logothetis DE, Vaidehi N, Dohlman HG. Knight KM, et al. Among authors: obarow eg. Cell Rep. 2023 Dec 26;42(12):113462. doi: 10.1016/j.celrep.2023.113462. Epub 2023 Nov 18. Cell Rep. 2023. PMID: 37980565 Free PMC article.