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Page 1
Integrated multi-omics analysis reveals molecular changes associated with chronic lipid accumulation following contusive spinal cord injury.
Yao XQ, Chen JY, Garcia-Segura ME, Wen ZH, Yu ZH, Huang ZC, Hamel R, Liu JH, Shen X, Huang ZP, Lu YM, Zhou ZT, Liu CT, Shi JM, Zhu QA, Peruzzotti-Jametti L, Chen JT. Yao XQ, et al. Among authors: garcia segura me. Exp Neurol. 2024 Oct;380:114909. doi: 10.1016/j.expneurol.2024.114909. Epub 2024 Aug 5. Exp Neurol. 2024. PMID: 39097074 Free article.
Mitochondrial complex I activity in microglia sustains neuroinflammation.
Peruzzotti-Jametti L, Willis CM, Krzak G, Hamel R, Pirvan L, Ionescu RB, Reisz JA, Prag HA, Garcia-Segura ME, Wu V, Xiang Y, Barlas B, Casey AM, van den Bosch AMR, Nicaise AM, Roth L, Bates GR, Huang H, Prasad P, Vincent AE, Frezza C, Viscomi C, Balmus G, Takats Z, Marioni JC, D'Alessandro A, Murphy MP, Mohorianu I, Pluchino S. Peruzzotti-Jametti L, et al. Among authors: garcia segura me. Nature. 2024 Apr;628(8006):195-203. doi: 10.1038/s41586-024-07167-9. Epub 2024 Mar 13. Nature. 2024. PMID: 38480879 Free PMC article.
Metabolic Control of Microglia.
Garcia-Segura ME, Pluchino S, Peruzzotti-Jametti L. Garcia-Segura ME, et al. Adv Neurobiol. 2024;37:607-622. doi: 10.1007/978-3-031-55529-9_34. Adv Neurobiol. 2024. PMID: 39207716 Review.
Dark Microglia Are Abundant in Normal Postnatal Development, where they Remodel Synapses via Phagocytosis and Trogocytosis, and Are Dependent on TREM2.
Vecchiarelli HA, Bisht K, Sharma K, Weiser Novak S, Traetta ME, Garcia-Segura ME, St-Pierre MK, Savage JC, Willis C, Picard K, Bordeleau M, Vernoux N, Khakpour M, Garg R, Loewen SM, Murray CJ, Grinberg YY, Faustino J, Halvorson T, Lau V, Pluchino S, Vexler ZS, Carson MJ, Manor U, Peruzzotti-Jametti L, Tremblay MÈ. Vecchiarelli HA, et al. Among authors: garcia segura me. bioRxiv [Preprint]. 2024 Oct 18:2024.10.15.618087. doi: 10.1101/2024.10.15.618087. bioRxiv. 2024. PMID: 39463930 Free PMC article. Preprint.
SUMOtherapeutics for Ischemic Stroke.
Karandikar P, Gerstl JVE, Kappel AD, Won SY, Dubinski D, Garcia-Segura ME, Gessler FA, See AP, Peruzzotti-Jametti L, Bernstock JD. Karandikar P, et al. Among authors: garcia segura me. Pharmaceuticals (Basel). 2023 Apr 29;16(5):673. doi: 10.3390/ph16050673. Pharmaceuticals (Basel). 2023. PMID: 37242456 Free PMC article. Review.
Integrative transcriptomic and metabolic analyses of the mammalian hibernating brain identifies a key role for succinate dehydrogenase in ischemic tolerance.
Bernstock JD, Willis CM, Garcia-Segura ME, Gaude E, Anni D, Lee YJ, Thomas LW, Casey A, Vicario N, Leonardi T, Nicaise AM, Gessler FA, Izzy S, Buffelli MR, Seidlitz J, Srinivasan S, Murphy MP, Ashcroft M, Cambiaghi M, Hallenbeck JM, Peruzzotti-Jametti L. Bernstock JD, et al. Among authors: garcia segura me. bioRxiv [Preprint]. 2023 Mar 30:2023.03.29.534718. doi: 10.1101/2023.03.29.534718. bioRxiv. 2023. PMID: 37205496 Free PMC article. Preprint.
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