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New potent muscarinic receptor ligands bearing the 1,4-dioxane nucleus: Investigation on the nature of the substituent in position 2.
Giorgioni G, Bonifazi A, Matucci R, Matteucci F, Piergentili A, Piergentili A, Quaglia W, Gervasoni S, Vistoli G, Vittorio S, Del Bello F. Giorgioni G, et al. Among authors: piergentili a. Arch Pharm (Weinheim). 2024 Oct;357(10):e2400337. doi: 10.1002/ardp.202400337. Epub 2024 Jul 25. Arch Pharm (Weinheim). 2024. PMID: 39054609
Synthesis, Biological, and Computational Evaluations of Conformationally Restricted NAD-Mimics as Discriminant Inhibitors of Human NMN-Adenylyltransferase Isozymes.
Matteucci F, Ferrati M, Spinozzi E, Piergentili A, Del Bello F, Giorgioni G, Sorci L, Petrelli R, Cappellacci L. Matteucci F, et al. Among authors: piergentili a. Pharmaceuticals (Basel). 2024 Jun 6;17(6):739. doi: 10.3390/ph17060739. Pharmaceuticals (Basel). 2024. PMID: 38931406 Free PMC article.
Copper-Based Complexes with Adamantane Ring-Conjugated bis(3,5-Dimethyl-pyrazol-1-yl)acetate Ligand as Promising Agents for the Treatment of Glioblastoma.
Morelli MB, Caviglia M, Santini C, Del Gobbo J, Zeppa L, Del Bello F, Giorgioni G, Piergentili A, Quaglia W, Battocchio C, Bertelà F, Amatori S, Meneghini C, Iucci G, Venditti I, Dolmella A, Di Palma M, Pellei M. Morelli MB, et al. Among authors: piergentili a. J Med Chem. 2024 Jun 13;67(11):9662-9685. doi: 10.1021/acs.jmedchem.4c00821. Epub 2024 Jun 3. J Med Chem. 2024. PMID: 38831692
Advances in drug design and therapeutic potential of selective or multitarget 5-HT1A receptor ligands.
Giorgioni G, Bonifazi A, Botticelli L, Cifani C, Matteucci F, Micioni Di Bonaventura E, Micioni Di Bonaventura MV, Giannella M, Piergentili A, Piergentili A, Quaglia W, Del Bello F. Giorgioni G, et al. Among authors: piergentili a. Med Res Rev. 2024 Nov;44(6):2640-2706. doi: 10.1002/med.22049. Epub 2024 May 29. Med Res Rev. 2024. PMID: 38808959 Review.
Properly Substituted Benzimidazoles as a New Promising Class of Nicotinate Phosphoribosyltransferase (NAPRT) Modulators.
Baldassarri C, Giorgioni G, Piergentili A, Quaglia W, Fontana S, Mammoli V, Minazzato G, Marangoni E, Gasparrini M, Sorci L, Raffaelli N, Cappellacci L, Petrelli R, Del Bello F. Baldassarri C, et al. Among authors: piergentili a. Pharmaceuticals (Basel). 2023 Jan 27;16(2):189. doi: 10.3390/ph16020189. Pharmaceuticals (Basel). 2023. PMID: 37259338 Free PMC article.
Targeting orexin receptors: Recent advances in the development of subtype selective or dual ligands for the treatment of neuropsychiatric disorders.
Bonifazi A, Del Bello F, Giorgioni G, Piergentili A, Saab E, Botticelli L, Cifani C, Micioni Di Bonaventura E, Micioni Di Bonaventura MV, Quaglia W. Bonifazi A, et al. Among authors: piergentili a. Med Res Rev. 2023 Sep;43(5):1607-1667. doi: 10.1002/med.21959. Epub 2023 Apr 10. Med Res Rev. 2023. PMID: 37036052 Review.
Investigating the role of the central melanocortin system in stress and stress-related disorders.
Micioni Di Bonaventura E, Botticelli L, Del Bello F, Giorgioni G, Piergentili A, Quaglia W, Romano A, Gaetani S, Micioni Di Bonaventura MV, Cifani C. Micioni Di Bonaventura E, et al. Among authors: piergentili a. Pharmacol Res. 2022 Nov;185:106521. doi: 10.1016/j.phrs.2022.106521. Epub 2022 Oct 20. Pharmacol Res. 2022. PMID: 36272641 Free article. Review.
Highly Potent and Selective Dopamine D4 Receptor Antagonists Potentially Useful for the Treatment of Glioblastoma.
Pavletić P, Semeano A, Yano H, Bonifazi A, Giorgioni G, Piergentili A, Quaglia W, Sabbieti MG, Agas D, Santoni G, Pallini R, Ricci-Vitiani L, Sabato E, Vistoli G, Del Bello F. Pavletić P, et al. Among authors: piergentili a. J Med Chem. 2022 Sep 22;65(18):12124-12139. doi: 10.1021/acs.jmedchem.2c00840. Epub 2022 Sep 13. J Med Chem. 2022. PMID: 36098685 Free PMC article.
93 results