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190 results

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Page 1
Normalization of Snai1-mediated vessel dysfunction increases drug response in cancer.
Hoffmann H, Wartenberg M, Vorlova S, Karl-Schöller F, Kallius M, Reinhardt O, Öztürk A, Schuhmair LS, Burkhardt V, Gätzner S, Scheld D, Nandigama R, Zernecke A, Herterich S, Ergün S, Rosenwald A, Henke E. Hoffmann H, et al. Among authors: zernecke a. Oncogene. 2024 Aug;43(35):2661-2676. doi: 10.1038/s41388-024-03113-1. Epub 2024 Aug 2. Oncogene. 2024. PMID: 39095583 Free PMC article.
LOX-catalyzed collagen stabilization is a proximal cause for intrinsic resistance to chemotherapy.
Rossow L, Veitl S, Vorlová S, Wax JK, Kuhn AE, Maltzahn V, Upcin B, Karl F, Hoffmann H, Gätzner S, Kallius M, Nandigama R, Scheld D, Irmak S, Herterich S, Zernecke A, Ergün S, Henke E. Rossow L, et al. Among authors: zernecke a. Oncogene. 2018 Sep;37(36):4921-4940. doi: 10.1038/s41388-018-0320-2. Epub 2018 May 21. Oncogene. 2018. PMID: 29780168 Free PMC article.
A vascularized breast cancer spheroid platform for the ranked evaluation of tumor microenvironment-targeted drugs by light sheet fluorescence microscopy.
Ascheid D, Baumann M, Pinnecker J, Friedrich M, Szi-Marton D, Medved C, Bundalo M, Ortmann V, Öztürk A, Nandigama R, Hemmen K, Ergün S, Zernecke A, Hirth M, Heinze KG, Henke E. Ascheid D, et al. Among authors: zernecke a. Nat Commun. 2024 Apr 27;15(1):3599. doi: 10.1038/s41467-024-48010-z. Nat Commun. 2024. PMID: 38678014 Free PMC article.
Targeting Elastase for Molecular Imaging of Early Atherosclerotic Lesions.
Glinzer A, Ma X, Prakash J, Kimm MA, Lohöfer F, Kosanke K, Pelisek J, Thon MP, Vorlova S, Heinze KG, Eckstein HH, Gee MW, Ntziachristos V, Zernecke A, Wildgruber M. Glinzer A, et al. Among authors: zernecke a. Arterioscler Thromb Vasc Biol. 2017 Mar;37(3):525-533. doi: 10.1161/ATVBAHA.116.308726. Epub 2016 Dec 29. Arterioscler Thromb Vasc Biol. 2017. PMID: 28062502
Interference with ERK-dimerization at the nucleocytosolic interface targets pathological ERK1/2 signaling without cardiotoxic side-effects.
Tomasovic A, Brand T, Schanbacher C, Kramer S, Hümmert MW, Godoy P, Schmidt-Heck W, Nordbeck P, Ludwig J, Homann S, Wiegering A, Shaykhutdinov T, Kratz C, Knüchel R, Müller-Hermelink HK, Rosenwald A, Frey N, Eichler J, Dobrev D, El-Armouche A, Hengstler JG, Müller OJ, Hinrichs K, Cuello F, Zernecke A, Lorenz K. Tomasovic A, et al. Among authors: zernecke a. Nat Commun. 2020 Apr 7;11(1):1733. doi: 10.1038/s41467-020-15505-4. Nat Commun. 2020. PMID: 32265441 Free PMC article.
CD8+ T Cells in Atherosclerosis.
Schäfer S, Zernecke A. Schäfer S, et al. Among authors: zernecke a. Cells. 2020 Dec 29;10(1):37. doi: 10.3390/cells10010037. Cells. 2020. PMID: 33383733 Free PMC article. Review.
190 results