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Page 1
In utero delivery of targeted ionizable lipid nanoparticles facilitates in vivo gene editing of hematopoietic stem cells.
Palanki R, Riley JS, Bose SK, Luks V, Dave A, Kus N, White BM, Ricciardi AS, Swingle KL, Xue L, Sung D, Thatte AS, Safford HC, Chaluvadi VS, Carpenter M, Han EL, Maganti R, Hamilton AG, Mrksich K, Billingsley MB, Zoltick PW, Alameh MG, Weissman D, Mitchell MJ, Peranteau WH. Palanki R, et al. Among authors: thatte as. Proc Natl Acad Sci U S A. 2024 Aug 6;121(32):e2400783121. doi: 10.1073/pnas.2400783121. Epub 2024 Jul 30. Proc Natl Acad Sci U S A. 2024. PMID: 39078677
Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy.
Swingle KL, Safford HC, Geisler HC, Hamilton AG, Thatte AS, Billingsley MM, Joseph RA, Mrksich K, Padilla MS, Ghalsasi AA, Alameh MG, Weissman D, Mitchell MJ. Swingle KL, et al. Among authors: thatte as. J Am Chem Soc. 2023 Mar 1;145(8):4691-4706. doi: 10.1021/jacs.2c12893. Epub 2023 Feb 15. J Am Chem Soc. 2023. PMID: 36789893 Free PMC article.
Bile acid-containing lipid nanoparticles enhance extrahepatic mRNA delivery.
Patel SK, Billingsley MM, Mukalel AJ, Thatte AS, Hamilton AG, Gong N, El-Mayta R, Safford HC, Merolle M, Mitchell MJ. Patel SK, et al. Among authors: thatte as. Theranostics. 2024 Jan 1;14(1):1-16. doi: 10.7150/thno.89913. eCollection 2024. Theranostics. 2024. PMID: 38164140 Free PMC article.
Emerging strategies for nanomedicine in autoimmunity.
Thatte AS, Billingsley MM, Weissman D, Melamed JR, Mitchell MJ. Thatte AS, et al. Adv Drug Deliv Rev. 2024 Apr;207:115194. doi: 10.1016/j.addr.2024.115194. Epub 2024 Feb 10. Adv Drug Deliv Rev. 2024. PMID: 38342243 Review.
Antigen Presenting Cell Mimetic Lipid Nanoparticles for Rapid mRNA CAR T Cell Cancer Immunotherapy.
Metzloff AE, Padilla MS, Gong N, Billingsley MM, Han X, Merolle M, Mai D, Figueroa-Espada CG, Thatte AS, Haley RM, Mukalel AJ, Hamilton AG, Alameh MG, Weissman D, Sheppard NC, June CH, Mitchell MJ. Metzloff AE, et al. Among authors: thatte as. Adv Mater. 2024 Jun;36(26):e2313226. doi: 10.1002/adma.202313226. Epub 2024 Mar 15. Adv Mater. 2024. PMID: 38419362
Ionizable Lipid Nanoparticle-Mediated TRAIL mRNA Delivery in the Tumor Microenvironment to Inhibit Colon Cancer Progression.
da Silva WN, Carvalho Costa PA, Scalzo Júnior SRA, Ferreira HAS, Prazeres PHDM, Campos CLV, Rodrigues Alves MT, Alves da Silva NJ, de Castro Santos AL, Guimarães LC, Chen Ferris ME, Thatte A, Hamilton A, Bicalho KA, Lobo AO, Santiago HDC, da Silva Barcelos L, Figueiredo MM, Teixeira MM, Vasconcelos Costa V, Mitchell MJ, Frézard F, Pires Goulart Guimaraes P. da Silva WN, et al. Int J Nanomedicine. 2024 Mar 14;19:2655-2673. doi: 10.2147/IJN.S452896. eCollection 2024. Int J Nanomedicine. 2024. PMID: 38500680 Free PMC article.
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