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NLRC5 senses NAD+ depletion, forming a PANoptosome and driving PANoptosis and inflammation.
Sundaram B, Pandian N, Kim HJ, Abdelaal HM, Mall R, Indari O, Sarkar R, Tweedell RE, Alonzo EQ, Klein J, Pruett-Miller SM, Vogel P, Kanneganti TD. Sundaram B, et al. Among authors: tweedell re. Cell. 2024 Jul 25;187(15):4061-4077.e17. doi: 10.1016/j.cell.2024.05.034. Epub 2024 Jun 14. Cell. 2024. PMID: 38878777 Free PMC article.
The NLR family of innate immune and cell death sensors.
Sundaram B, Tweedell RE, Prasanth Kumar S, Kanneganti TD. Sundaram B, et al. Among authors: tweedell re. Immunity. 2024 Apr 9;57(4):674-699. doi: 10.1016/j.immuni.2024.03.012. Immunity. 2024. PMID: 38599165 Free article. Review.
21 results