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Mapping the genetic landscape establishing a tumor immune microenvironment favorable for anti-PD-1 response in mice and humans.
Skelly DA, Graham JP, Cheng M, Furuta M, Walter A, Stoklasek TA, Yang H, Stearns TM, Poirion O, Zhang JG, Grassmann JDS, Luo D, Flynn WF, Courtois ET, Chang CH, Serreze DV, Menghi F, Reinholdt LG, Liu ET. Skelly DA, et al. Among authors: flynn wf. bioRxiv [Preprint]. 2024 Jul 16:2024.07.11.603136. doi: 10.1101/2024.07.11.603136. bioRxiv. 2024. PMID: 39071392 Free PMC article. Preprint.
Single nucleus transcriptomics, pharmacokinetics, and pharmacodynamics of combined CDK4/6 and mTOR inhibition in a phase 0/1 trial of recurrent high-grade glioma.
Johnson KC, Tien AC, Jiang J, McNamara J, Chang YW, Montgomery C, DeSantis A, Elena-Sanchez L, Fujita Y, Kim S, Spitzer A, Gabriel P, Flynn WF, Courtois ET, Hong A, Harmon J, Umemura Y, Tovmasyan A, Li J, Mehta S, Verhaak R, Sanai N. Johnson KC, et al. Among authors: flynn wf. medRxiv [Preprint]. 2024 Jun 7:2024.06.07.24308439. doi: 10.1101/2024.06.07.24308439. medRxiv. 2024. PMID: 38883740 Free PMC article. Preprint.
Clearance of p21 highly expressing senescent cells accelerates cutaneous wound healing.
Gasek NS, Yan P, Zhu J, Purushothaman KR, Kim T, Wang L, Wang B, Flynn WF, Sun M, Guo C, Huggins B, Sharafieh R, Zhou Y, Parizek V, Tchkonia T, Kirkland JL, Wyles SP, Xu M. Gasek NS, et al. Among authors: flynn wf. Nat Aging. 2024 Nov 13. doi: 10.1038/s43587-024-00755-4. Online ahead of print. Nat Aging. 2024. PMID: 39537987
Author Correction: Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP).
Jain S, Pei L, Spraggins JM, Angelo M, Carson JP, Gehlenborg N, Ginty F, Gonçalves JP, Hagood JS, Hickey JW, Kelleher NL, Laurent LC, Lin S, Lin Y, Liu H, Naba A, Nakayasu ES, Qian WJ, Radtke A, Robson P, Stockwell BR, Van de Plas R, Vlachos IS, Zhou M; HuBMAP Consortium; Börner K, Snyder MP. Jain S, et al. Nat Cell Biol. 2024 May;26(5):839. doi: 10.1038/s41556-024-01384-0. Nat Cell Biol. 2024. PMID: 38429479 No abstract available.
Patient-Derived Models of Cancer in the NCI PDMC Consortium: Selection, Pitfalls, and Practical Recommendations.
Habowski AN, Budagavi DP, Scherer SD, Aurora AB, Caligiuri G, Flynn WF, Langer EM, Brody JR, Sears RC, Foggetti G, Arnal Estape A, Nguyen DX, Politi KA, Shen X, Hsu DS, Peehl DM, Kurhanewicz J, Sriram R, Suarez M, Xiao S, Du Y, Li XN, Navone NM, Labanca E, Willey CD. Habowski AN, et al. Among authors: flynn wf. Cancers (Basel). 2024 Jan 29;16(3):565. doi: 10.3390/cancers16030565. Cancers (Basel). 2024. PMID: 38339316 Free PMC article. Review.
Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP).
Jain S, Pei L, Spraggins JM, Angelo M, Carson JP, Gehlenborg N, Ginty F, Gonçalves JP, Hagood JS, Hickey JW, Kelleher NL, Laurent LC, Lin S, Lin Y, Liu H, Naba A, Nakayasu ES, Qian WJ, Radtke A, Robson P, Stockwell BR, Van de Plas R, Vlachos IS, Zhou M; HuBMAP Consortium; Börner K, Snyder MP. Jain S, et al. Nat Cell Biol. 2023 Aug;25(8):1089-1100. doi: 10.1038/s41556-023-01194-w. Epub 2023 Jul 19. Nat Cell Biol. 2023. PMID: 37468756 Free PMC article. Review.
Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target.
Abdelfattah N, Kumar P, Wang C, Leu JS, Flynn WF, Gao R, Baskin DS, Pichumani K, Ijare OB, Wood SL, Powell SZ, Haviland DL, Parker Kerrigan BC, Lang FF, Prabhu SS, Huntoon KM, Jiang W, Kim BYS, George J, Yun K. Abdelfattah N, et al. Among authors: flynn wf. Nat Commun. 2022 Feb 9;13(1):767. doi: 10.1038/s41467-022-28372-y. Nat Commun. 2022. PMID: 35140215 Free PMC article.
36 results