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Page 1
Extracellular vesicles from primary human macrophages stimulated with VIP or PACAP mediate anti-SARS-CoV-2 activities in monocytes through NF-κB signaling pathway.
Arteaga-Blanco LA, Temerozo JR, Tiné LPS, Dantas-Pereira L, Sacramento CQ, Fintelman-Rodrigues N, Toja BM, Gomes Dias SS, de Freitas CS, Espírito-Santo CC, Silva YP, Frozza RL, Bozza PT, Menna-Barreto RFS, Souza TML, Bou-Habib DC. Arteaga-Blanco LA, et al. Among authors: de freitas cs. Microbes Infect. 2024 Nov-Dec;26(8):105400. doi: 10.1016/j.micinf.2024.105400. Epub 2024 Jul 26. Microbes Infect. 2024. PMID: 39069117
Atazanavir, Alone or in Combination with Ritonavir, Inhibits SARS-CoV-2 Replication and Proinflammatory Cytokine Production.
Fintelman-Rodrigues N, Sacramento CQ, Ribeiro Lima C, Souza da Silva F, Ferreira AC, Mattos M, de Freitas CS, Cardoso Soares V, da Silva Gomes Dias S, Temerozo JR, Miranda MD, Matos AR, Bozza FA, Carels N, Alves CR, Siqueira MM, Bozza PT, Souza TML. Fintelman-Rodrigues N, et al. Among authors: de freitas cs. Antimicrob Agents Chemother. 2020 Sep 21;64(10):e00825-20. doi: 10.1128/AAC.00825-20. Print 2020 Sep 21. Antimicrob Agents Chemother. 2020. PMID: 32759267 Free PMC article.
Lipid droplets fuel SARS-CoV-2 replication and production of inflammatory mediators.
Dias SSG, Soares VC, Ferreira AC, Sacramento CQ, Fintelman-Rodrigues N, Temerozo JR, Teixeira L, Nunes da Silva MA, Barreto E, Mattos M, de Freitas CS, Azevedo-Quintanilha IG, Manso PPA, Miranda MD, Siqueira MM, Hottz ED, Pão CRR, Bou-Habib DC, Barreto-Vieira DF, Bozza FA, Souza TML, Bozza PT. Dias SSG, et al. Among authors: de freitas cs. PLoS Pathog. 2020 Dec 16;16(12):e1009127. doi: 10.1371/journal.ppat.1009127. eCollection 2020 Dec. PLoS Pathog. 2020. PMID: 33326472 Free PMC article.
SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes.
Ferreira AC, Soares VC, de Azevedo-Quintanilha IG, Dias SDSG, Fintelman-Rodrigues N, Sacramento CQ, Mattos M, de Freitas CS, Temerozo JR, Teixeira L, Damaceno Hottz E, Barreto EA, Pão CRR, Palhinha L, Miranda M, Bou-Habib DC, Bozza FA, Bozza PT, Souza TML. Ferreira AC, et al. Among authors: de freitas cs, de azevedo quintanilha ig. Cell Death Discov. 2021 Mar 1;7(1):43. doi: 10.1038/s41420-021-00428-w. Cell Death Discov. 2021. PMID: 33649297 Free PMC article.
In vitro antiviral activity of the anti-HCV drugs daclatasvir and sofosbuvir against SARS-CoV-2, the aetiological agent of COVID-19.
Sacramento CQ, Fintelman-Rodrigues N, Temerozo JR, Da Silva APD, Dias SDSG, da Silva CDS, Ferreira AC, Mattos M, Pão CRR, de Freitas CS, Soares VC, Hoelz LVB, Fernandes TVA, Branco FSC, Bastos MM, Boechat N, Saraiva FB, Ferreira MA, Jockusch S, Wang X, Tao C, Chien M, Xie W, Patel D, Garzia A, Tuschl T, Russo JJ, Rajoli RKR, Pedrosa CSG, Vitória G, Souza LRQ, Goto-Silva L, Guimarães MZ, Rehen SK, Owen A, Bozza FA, Bou-Habib DC, Ju J, Bozza PT, Souza TML. Sacramento CQ, et al. Among authors: de freitas cs. J Antimicrob Chemother. 2021 Jun 18;76(7):1874-1885. doi: 10.1093/jac/dkab072. J Antimicrob Chemother. 2021. PMID: 33880524 Free PMC article.
Correction: SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes.
Ferreira AC, Soares VC, de Azevedo-Quintanilha IG, Dias SDSG, Fintelman-Rodrigues N, Sacramento CQ, Mattos M, de Freitas CS, Temerozo JR, Teixeira L, Hottz ED, Barreto EA, Pão CRR, Palhinha L, Miranda M, Bou-Habib DC, Bozza FA, Bozza PT, Souza TML. Ferreira AC, et al. Among authors: de freitas cs, de azevedo quintanilha ig. Cell Death Discov. 2021 May 19;7(1):116. doi: 10.1038/s41420-021-00477-1. Cell Death Discov. 2021. PMID: 34011951 Free PMC article. No abstract available.
Simvastatin Downregulates the SARS-CoV-2-Induced Inflammatory Response and Impairs Viral Infection Through Disruption of Lipid Rafts.
Teixeira L, Temerozo JR, Pereira-Dutra FS, Ferreira AC, Mattos M, Gonçalves BS, Sacramento CQ, Palhinha L, Cunha-Fernandes T, Dias SSG, Soares VC, Barreto EA, Cesar-Silva D, Fintelman-Rodrigues N, Pão CRR, de Freitas CS, Reis PA, Hottz ED, Bozza FA, Bou-Habib DC, Saraiva EM, de Almeida CJG, Viola JPB, Souza TML, Bozza PT. Teixeira L, et al. Among authors: de freitas cs, de almeida cjg. Front Immunol. 2022 Feb 18;13:820131. doi: 10.3389/fimmu.2022.820131. eCollection 2022. Front Immunol. 2022. PMID: 35251001 Free PMC article.
VIP plasma levels associate with survival in severe COVID-19 patients, correlating with protective effects in SARS-CoV-2-infected cells.
Temerozo JR, Sacramento CQ, Fintelman-Rodrigues N, Pão CRR, de Freitas CS, Dias SSG, Ferreira AC, Mattos M, Soares VC, Teixeira L, Azevedo-Quintanilha IG, Hottz ED, Kurtz P, Bozza FA, Bozza PT, Souza TML, Bou-Habib DC. Temerozo JR, et al. Among authors: de freitas cs. J Leukoc Biol. 2022 May;111(5):1107-1121. doi: 10.1002/JLB.5COVA1121-626R. Epub 2022 Mar 24. J Leukoc Biol. 2022. PMID: 35322471 Free PMC article.
Agathisflavone, a natural biflavonoid that inhibits SARS-CoV-2 replication by targeting its proteases.
Chaves OA, Lima CR, Fintelman-Rodrigues N, Sacramento CQ, de Freitas CS, Vazquez L, Temerozo JR, Rocha MEN, Dias SSG, Carels N, Bozza PT, Castro-Faria-Neto HC, Souza TML. Chaves OA, et al. Among authors: de freitas cs. Int J Biol Macromol. 2022 Dec 1;222(Pt A):1015-1026. doi: 10.1016/j.ijbiomac.2022.09.204. Epub 2022 Sep 29. Int J Biol Macromol. 2022. PMID: 36183752 Free PMC article.
Severe influenza infection is associated with inflammatory programmed cell death in infected macrophages.
Ferreira AC, Sacramento CQ, Pereira-Dutra FS, Fintelman-Rodrigues N, Silva PP, Mattos M, de Freitas CS, Marttorelli A, de Melo GR, Campos MM, Azevedo-Quintanilha IG, Carlos AS, Emídio JV, Garcia CC, Bozza PT, Bozza FA, Souza TML. Ferreira AC, et al. Among authors: de freitas cs. Front Cell Infect Microbiol. 2023 Feb 16;13:1067285. doi: 10.3389/fcimb.2023.1067285. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 36875528 Free PMC article.
35 results