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Page 1
The Mitragyna speciosa (kratom) alkaloid mitragynine: Analysis of adrenergic α2 receptor activity in vitro and in vivo.
Obeng S, Crowley ML, Mottinelli M, León F, Zuarth Gonzalez JD, Chen Y, Gamez-Jimenez LR, Restrepo LF, Ho NP, Patel A, Martins Rocha J, Alvarez MA, Thadisetti AM, Park CR, Pallares VLC, Milner MJ, Canal CE, Hampson AJ, McCurdy CR, McMahon LR, Wilkerson JL, Hiranita T. Obeng S, et al. Among authors: crowley ml. Eur J Pharmacol. 2024 Oct 5;980:176863. doi: 10.1016/j.ejphar.2024.176863. Epub 2024 Jul 26. Eur J Pharmacol. 2024. PMID: 39068978 Free PMC article.
Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats.
Obeng S, Wilkerson JL, León F, Reeves ME, Restrepo LF, Gamez-Jimenez LR, Patel A, Pennington AE, Taylor VA, Ho NP, Braun T, Fortner JD, Crowley ML, Williamson MR, Pallares VLC, Mottinelli M, Lopera-Londoño C, McCurdy CR, McMahon LR, Hiranita T. Obeng S, et al. Among authors: crowley ml. J Pharmacol Exp Ther. 2021 Mar;376(3):410-427. doi: 10.1124/jpet.120.000189. Epub 2020 Dec 31. J Pharmacol Exp Ther. 2021. PMID: 33384303 Free PMC article.
Classics in Chemical Neuroscience: Medetomidine.
de Andrade Horn P, Berida TI, Parr LC, Bouchard JL, Jayakodiarachchi N, Schultz DC, Lindsley CW, Crowley ML. de Andrade Horn P, et al. Among authors: crowley ml. ACS Chem Neurosci. 2024 Nov 6;15(21):3874-3883. doi: 10.1021/acschemneuro.4c00583. Epub 2024 Oct 15. ACS Chem Neurosci. 2024. PMID: 39405508 Free PMC article. Review.
Polyamine-based small molecule epigenetic modulators.
Sharma SK, Hazeldine S, Crowley ML, Hanson A, Beattie R, Varghese S, Senanayake TM, Hirata A, Hirata F, Huang Y, Wu Y, Steinbergs N, Murray-Stewart T, Bytheway I, Casero RA Jr, Woster PM. Sharma SK, et al. Among authors: crowley ml. Medchemcomm. 2012;3(1):14-21. doi: 10.1039/C1MD00220A. Epub 2011 Nov 26. Medchemcomm. 2012. PMID: 23293738 Free PMC article.