Canal CE - Search Results

1

The Mitragyna speciosa (kratom) alkaloid mitragynine: Analysis of adrenergic α₂ receptor activity in vitro and in vivo.

Obeng S, Crowley ML, Mottinelli M, León F, Zuarth Gonzalez JD, Chen Y, Gamez-Jimenez LR, Restrepo LF, Ho NP, Patel A, Martins Rocha J, Alvarez MA, Thadisetti AM, Park CR, Pallares VLC, Milner MJ, Canal CE, Hampson AJ, McCurdy CR, McMahon LR, Wilkerson JL, Hiranita T. Obeng S, et al. Among authors: canal ce. Eur J Pharmacol. 2024 Oct 5;980:176863. doi: 10.1016/j.ejphar.2024.176863. Epub 2024 Jul 26. Eur J Pharmacol. 2024. PMID: 39068978 Free PMC article.

2

Defined radio wave frequencies attenuate the head-twitch response in mice elicited by (±)-2,5-dimethoxy-4-iodoamphetamine.

Vu MO, Butters BM, Canal CE, Figueroa XA. Vu MO, et al. Among authors: canal ce. Electromagn Biol Med. 2024 Oct;43(4):328-336. doi: 10.1080/15368378.2024.2418552. Epub 2024 Oct 22. Electromagn Biol Med. 2024. PMID: 39435614

3

Synthesis and Structure-Activity Relationships of 2,5-Dimethoxy-4-Substituted Phenethylamines and the Discovery of CYB210010: A Potent, Orally Bioavailable and Long-Acting Serotonin 5-HT₂ Receptor Agonist.

Varty GB, Canal CE, Mueller TA, Hartsel JA, Tyagi R, Avery K, Morgan ME, Reichelt AC, Pathare P, Stang E, Palfreyman MG, Nivorozhkin A. Varty GB, et al. Among authors: canal ce. J Med Chem. 2024 Apr 25;67(8):6144-6188. doi: 10.1021/acs.jmedchem.3c01961. Epub 2024 Apr 9. J Med Chem. 2024. PMID: 38593423

4

Altered brain serotonin 5-HT_1A receptor expression and function in juvenile Fmr1 knockout mice.

Saraf TS, Chen Y, Tyagi R, Canal CE. Saraf TS, et al. Among authors: canal ce. Neuropharmacology. 2024 Mar 1;245:109774. doi: 10.1016/j.neuropharm.2023.109774. Epub 2023 Nov 3. Neuropharmacology. 2024. PMID: 37923121

5

The Psychedelic N,N-Dipropyltryptamine Prevents Seizures in a Mouse Model of Fragile X Syndrome via a Mechanism that Appears Independent of Serotonin and Sigma1 Receptors.

Tyagi R, Saraf TS, Canal CE. Tyagi R, et al. Among authors: canal ce. ACS Pharmacol Transl Sci. 2023 Sep 18;6(10):1480-1491. doi: 10.1021/acsptsci.3c00137. eCollection 2023 Oct 13. ACS Pharmacol Transl Sci. 2023. PMID: 37854624 Free PMC article.

6

FPT, a 2-Aminotetralin, Is a Potent Serotonin 5-HT_1A, 5-HT_1B, and 5-HT_1D Receptor Agonist That Modulates Cortical Electroencephalogram Activity in Adult Fmr1 Knockout Mice.

Saraf TS, McGlynn RP, Bhatavdekar OM, Booth RG, Canal CE. Saraf TS, et al. Among authors: canal ce. ACS Chem Neurosci. 2022 Dec 21;13(24):3629-3640. doi: 10.1021/acschemneuro.2c00574. Epub 2022 Dec 6. ACS Chem Neurosci. 2022. PMID: 36473166 Free PMC article.

7

"Selective" serotonin 5-HT_2A receptor antagonists.

Casey AB, Cui M, Booth RG, Canal CE. Casey AB, et al. Among authors: canal ce. Biochem Pharmacol. 2022 Jun;200:115028. doi: 10.1016/j.bcp.2022.115028. Epub 2022 Apr 4. Biochem Pharmacol. 2022. PMID: 35381208 Free PMC article. Review.

8

Spontaneous seizures in adult Fmr1 knockout mice: FVB.129P2-Pde6b⁺Tyr^c-chFmr1^tm1Cgr/J.

Armstrong JL, Saraf TS, Bhatavdekar O, Canal CE. Armstrong JL, et al. Among authors: canal ce. Epilepsy Res. 2022 May;182:106891. doi: 10.1016/j.eplepsyres.2022.106891. Epub 2022 Mar 8. Epilepsy Res. 2022. PMID: 35290907 Free PMC article.

9

The Need To Improve Reporting of the Pharmacological Action of New Molecules.

Canal CE, Leopoldo M. Canal CE, et al. ACS Chem Neurosci. 2022 Jan 19;13(2):185-186. doi: 10.1021/acschemneuro.1c00829. Epub 2022 Jan 6. ACS Chem Neurosci. 2022. PMID: 34989567

10

Activity of Mitragyna speciosa ("Kratom") Alkaloids at Serotonin Receptors.

León F, Obeng S, Mottinelli M, Chen Y, King TI, Berthold EC, Kamble SH, Restrepo LF, Patel A, Gamez-Jimenez LR, Lopera-Londoño C, Hiranita T, Sharma A, Hampson AJ, Canal CE, McMahon LR, McCurdy CR. León F, et al. Among authors: canal ce. J Med Chem. 2021 Sep 23;64(18):13510-13523. doi: 10.1021/acs.jmedchem.1c00726. Epub 2021 Sep 1. J Med Chem. 2021. PMID: 34467758 Free PMC article.

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