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2-Phenoxy-3-Trichloromethylquinoxalines Are Antiplasmodial Derivatives with Activity against the Apicoplast of Plasmodium falciparum.
Amrane D, Arnold CS, Hutter S, Sanz-Serrano J, Collia M, Azqueta A, Paloque L, Cohen A, Amanzougaghene N, Tajeri S, Franetich JF, Mazier D, Benoit-Vical F, Verhaeghe P, Azas N, Vanelle P, Botté C, Primas N. Amrane D, et al. Among authors: azas n. Pharmaceuticals (Basel). 2021 Jul 26;14(8):724. doi: 10.3390/ph14080724. Pharmaceuticals (Basel). 2021. PMID: 34451821 Free PMC article.
4-Substituted Thieno[3,2-d]pyrimidines as Dual-Stage Antiplasmodial Derivatives.
Lagardère P, Mustière R, Amanzougaghene N, Hutter S, Franetich JF, Azas N, Vanelle P, Verhaeghe P, Primas N, Mazier D, Masurier N, Lisowski V. Lagardère P, et al. Among authors: azas n. Pharmaceuticals (Basel). 2022 Jul 1;15(7):820. doi: 10.3390/ph15070820. Pharmaceuticals (Basel). 2022. PMID: 35890119 Free PMC article.
Improving Aqueous Solubility and In Vitro Pharmacokinetic Properties of the 3-Nitroimidazo[1,2-a]pyridine Antileishmanial Pharmacophore.
Paoli-Lombardo R, Primas N, Bourgeade-Delmas S, Hutter S, Sournia-Saquet A, Boudot C, Brenot E, Castera-Ducros C, Corvaisier S, Since M, Malzert-Fréon A, Courtioux B, Valentin A, Verhaeghe P, Azas N, Rathelot P, Vanelle P. Paoli-Lombardo R, et al. Among authors: azas n. Pharmaceuticals (Basel). 2022 Aug 13;15(8):998. doi: 10.3390/ph15080998. Pharmaceuticals (Basel). 2022. PMID: 36015146 Free PMC article.
Original quinazoline derivatives displaying antiplasmodial properties.
Kabri Y, Azas N, Dumètre A, Hutter S, Laget M, Verhaeghe P, Gellis A, Vanelle P. Kabri Y, et al. Among authors: azas n. Eur J Med Chem. 2010 Feb;45(2):616-22. doi: 10.1016/j.ejmech.2009.11.005. Epub 2009 Nov 6. Eur J Med Chem. 2010. PMID: 19926173
Discovery of a new antileishmanial hit in 8-nitroquinoline series.
Paloque L, Verhaeghe P, Casanova M, Castera-Ducros C, Dumètre A, Mbatchi L, Hutter S, Kraiem-M'rabet M, Laget M, Remusat V, Rault S, Rathelot P, Azas N, Vanelle P. Paloque L, et al. Among authors: azas n. Eur J Med Chem. 2012 Aug;54:75-86. doi: 10.1016/j.ejmech.2012.04.029. Epub 2012 May 2. Eur J Med Chem. 2012. PMID: 22608675
97 results