Jacob J - Search Results

1

The Evolving Paradigm of Antibody-Drug Conjugates Targeting the ErbB/HER Family of Receptor Tyrosine Kinases.

High P, Guernsey C, Subramanian S, Jacob J, Carmon KS. High P, et al. Among authors: jacob j. Pharmaceutics. 2024 Jul 2;16(7):890. doi: 10.3390/pharmaceutics16070890. Pharmaceutics. 2024. PMID: 39065587 Free PMC article. Review.

2

Anti-GPR56 monoclonal antibody potentiates GPR56-mediated Src-Fak signaling to modulate cell adhesion.

Chatterjee T, Zhang S, Posey TA, Jacob J, Wu L, Yu W, Francisco LE, Liu QJ, Carmon KS. Chatterjee T, et al. Among authors: jacob j. J Biol Chem. 2021 Jan-Jun;296:100261. doi: 10.1016/j.jbc.2021.100261. Epub 2021 Jan 8. J Biol Chem. 2021. PMID: 33837725 Free PMC article.

3

Drug Conjugates of Antagonistic R-Spondin 4 Mutant for Simultaneous Targeting of Leucine-Rich Repeat-Containing G Protein-Coupled Receptors 4/5/6 for Cancer Treatment.

Cui J, Toh Y, Park S, Yu W, Tu J, Wu L, Li L, Jacob J, Pan S, Carmon KS, Liu QJ. Cui J, et al. Among authors: jacob j. J Med Chem. 2021 Sep 9;64(17):12572-12581. doi: 10.1021/acs.jmedchem.1c00395. Epub 2021 Aug 18. J Med Chem. 2021. PMID: 34406767 Free PMC article.

4

An antibody-drug conjugate targeting GPR56 demonstrates efficacy in preclinical models of colorectal cancer.

Jacob J, Francisco LE, Chatterjee T, Liang Z, Subramanian S, Liu QJ, Rowe JH, Carmon KS. Jacob J, et al. Br J Cancer. 2023 Apr;128(8):1592-1602. doi: 10.1038/s41416-023-02192-3. Epub 2023 Feb 9. Br J Cancer. 2023. PMID: 36759728 Free PMC article.

5

Loss of LGR5 through Therapy-induced Downregulation or Gene Ablation Is Associated with Resistance and Enhanced MET-STAT3 Signaling in Colorectal Cancer Cells.

Posey TA, Jacob J, Parkhurst A, Subramanian S, Francisco LE, Liang Z, Carmon KS. Posey TA, et al. Among authors: jacob j. Mol Cancer Ther. 2023 May 4;22(5):667-678. doi: 10.1158/1535-7163.MCT-22-0415. Mol Cancer Ther. 2023. PMID: 36921315 Free PMC article.

6

Antitumor Activity of a Pyrrolobenzodiazepine Antibody-Drug Conjugate Targeting LGR5 in Preclinical Models of Neuroblastoma.

Tu J, Toh Y, Aldana AM, Wen JJ, Wu L, Jacob J, Li L, Pan S, Carmon KS, Liu QJ. Tu J, et al. Among authors: jacob j. Pharmaceutics. 2024 Jul 15;16(7):943. doi: 10.3390/pharmaceutics16070943. Pharmaceutics. 2024. PMID: 39065640 Free PMC article.

7

G protein selectivity profile of GPR56/ADGRG1 and its effect on downstream effectors.

Jallouli R, Moreno-Salinas AL, Laniel A, Holleran B, Avet C, Jacob J, Hoang T, Lavoie C, Carmon KS, Bouvier M, Leduc R. Jallouli R, et al. Among authors: jacob j. Cell Mol Life Sci. 2024 Sep 4;81(1):383. doi: 10.1007/s00018-024-05416-8. Cell Mol Life Sci. 2024. PMID: 39231834 Free PMC article.

8

G protein selectivity profile of GPR56/ADGRG1 and its effect on downstream effectors.

Jallouli R, Moreno Salinas AL, Laniel A, Holleran B, Avet C, Jacob J, Hoang T, Lavoie C, Carmon KS, Bouvier M, Leduc R. Jallouli R, et al. Among authors: jacob j. Res Sq [Preprint]. 2024 Sep 5:rs.3.rs-4869264. doi: 10.21203/rs.3.rs-4869264/v1. Res Sq. 2024. Update in: Cell Mol Life Sci. 2024 Sep 4;81(1):383. doi: 10.1007/s00018-024-05416-8 PMID: 39281883 Free PMC article. Updated. Preprint.

9

Antibody-Drug Conjugates Targeting the EGFR Ligand Epiregulin Elicit Robust Anti-Tumor Activity in Colorectal Cancer.

Jacob J, Anami Y, High P, Liang Z, Subramanian S, Ghosh SC, AghaAmiri S, Guernsey-Biddle C, Tran H, Rowe JH, Azhdarinia A, Tsuchikama K, Carmon KS. Jacob J, et al. bioRxiv [Preprint]. 2024 Nov 21:2024.02.20.581056. doi: 10.1101/2024.02.20.581056. bioRxiv. 2024. Update in: Cancer Res. 2024 Dec 18. doi: 10.1158/0008-5472.CAN-24-0798 PMID: 39605519 Free PMC article. Updated. Preprint.

10

Antibody-Drug Conjugates Targeting the EGFR Ligand Epiregulin Elicit Robust Anti-Tumor Activity in Colorectal Cancer.

Jacob J, Anami Y, High PC, Liang Z, Subramanian S, Ghosh SC, AghaAmiri S, Guernsey-Biddle C, Tran H, Rowe J, Azhdarinia A, Tsuchikama K, Carmon KS. Jacob J, et al. Cancer Res. 2024 Dec 18. doi: 10.1158/0008-5472.CAN-24-0798. Online ahead of print. Cancer Res. 2024. PMID: 39693606

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

3,047 results

Search Page

Filters