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Page 1
Antibodies to the SARS-CoV-2 receptor-binding domain that maximize breadth and resistance to viral escape.
Starr TN, Czudnochowski N, Zatta F, Park YJ, Liu Z, Addetia A, Pinto D, Beltramello M, Hernandez P, Greaney AJ, Marzi R, Glass WG, Zhang I, Dingens AS, Bowen JE, Wojcechowskyj JA, De Marco A, Rosen LE, Zhou J, Montiel-Ruiz M, Kaiser H, Tucker H, Housley MP, di Iulio J, Lombardo G, Agostini M, Sprugasci N, Culap K, Jaconi S, Meury M, Dellota E, Cameroni E, Croll TI, Nix JC, Havenar-Daughton C, Telenti A, Lempp FA, Pizzuto MS, Chodera JD, Hebner CM, Whelan SPJ, Virgin HW, Veesler D, Corti D, Bloom JD, Snell G. Starr TN, et al. Among authors: addetia a. bioRxiv [Preprint]. 2021 Apr 8:2021.04.06.438709. doi: 10.1101/2021.04.06.438709. bioRxiv. 2021. Update in: Nature. 2021 Sep;597(7874):97-102. doi: 10.1038/s41586-021-03807-6 PMID: 33851154 Free PMC article. Updated. Preprint.
Structural basis for broad sarbecovirus neutralization by a human monoclonal antibody.
Tortorici MA, Czudnochowski N, Starr TN, Marzi R, Walls AC, Zatta F, Bowen JE, Jaconi S, di Iulio J, Wang Z, De Marco A, Zepeda SK, Pinto D, Liu Z, Beltramello M, Bartha I, Housley MP, Lempp FA, Rosen LE, Dellota E Jr, Kaiser H, Montiel-Ruiz M, Zhou J, Addetia A, Guarino B, Culap K, Sprugasci N, Saliba C, Vetti E, Giacchetto-Sasselli I, Silacci Fregni C, Abdelnabi R, Caroline Foo SY, Havenar-Daughton C, Schmid MA, Benigni F, Cameroni E, Neyts J, Telenti A, Snell G, Virgin HW, Whelan SPJ, Bloom JD, Corti D, Veesler D, Pizzuto MS. Tortorici MA, et al. Among authors: addetia a. bioRxiv [Preprint]. 2021 Apr 8:2021.04.07.438818. doi: 10.1101/2021.04.07.438818. bioRxiv. 2021. Update in: Nature. 2021 Sep;597(7874):103-108. doi: 10.1038/s41586-021-03817-4 PMID: 33851169 Free PMC article. Updated. Preprint.
Multivalent designed proteins protect against SARS-CoV-2 variants of concern.
Hunt AC, Case JB, Park YJ, Cao L, Wu K, Walls AC, Liu Z, Bowen JE, Yeh HW, Saini S, Helms L, Zhao YT, Hsiang TY, Starr TN, Goreshnik I, Kozodoy L, Carter L, Ravichandran R, Green LB, Matochko WL, Thomson CA, Vögeli B, Krüger-Gericke A, VanBlargan LA, Chen RE, Ying B, Bailey AL, Kafai NM, Boyken S, Ljubetič A, Edman N, Ueda G, Chow C, Addetia A, Panpradist N, Gale M Jr, Freedman BS, Lutz BR, Bloom JD, Ruohola-Baker H, Whelan SPJ, Stewart L, Diamond MS, Veesler D, Jewett MC, Baker D. Hunt AC, et al. Among authors: addetia a. bioRxiv [Preprint]. 2021 Jul 7:2021.07.07.451375. doi: 10.1101/2021.07.07.451375. bioRxiv. 2021. Update in: Sci Transl Med. 2022 May 25;14(646):eabn1252. doi: 10.1126/scitranslmed.abn1252 PMID: 34268509 Free PMC article. Updated. Preprint.
Structural changes in the SARS-CoV-2 spike E406W mutant escaping a clinical monoclonal antibody cocktail.
Addetia A, Park YJ, Starr T, Greaney AJ, Sprouse KR, Bowen JE, Tiles SW, Van Voorhis WC, Bloom JD, Corti D, Walls AC, Veesler D. Addetia A, et al. bioRxiv [Preprint]. 2022 Jan 25:2022.01.21.477288. doi: 10.1101/2022.01.21.477288. bioRxiv. 2022. Update in: Cell Rep. 2023 Jun 27;42(6):112621. doi: 10.1016/j.celrep.2023.112621 PMID: 35118471 Free PMC article. Updated. Preprint.
Imprinted antibody responses against SARS-CoV-2 Omicron sublineages.
Park YJ, Pinto D, Walls AC, Liu Z, Marco A, Benigni F, Zatta F, Silacci-Fregni C, Bassi J, Sprouse KR, Addetia A, Bowen JE, Stewart C, Giurdanella M, Saliba C, Guarino B, Schmid MA, Franko N, Logue J, Dang HV, Hauser K, Iulio JD, Rivera W, Schnell G, Rajesh A, Zhou J, Farhat N, Kaiser H, Montiel-Ruiz M, Noack J, Lempp FA, Janer J, Abdelnabi R, Maes P, Ferrari P, Ceschi A, Giannini O, de Melo GD, Kergoat L, Bourhy H, Neyts J, Soriaga L, Purcell LA, Snell G, Whelan SPJ, Lanzavecchia A, Virgin HW, Piccoli L, Chu H, Pizzuto MS, Corti D, Veesler D. Park YJ, et al. Among authors: addetia a. bioRxiv [Preprint]. 2022 Aug 22:2022.05.08.491108. doi: 10.1101/2022.05.08.491108. bioRxiv. 2022. Update in: Science. 2022 Nov 11;378(6620):619-627. doi: 10.1126/science.adc9127 PMID: 35677069 Free PMC article. Updated. Preprint.
Protein nanoparticle vaccines induce potent neutralizing antibody responses against MERS-CoV.
Chao CW, Sprouse KR, Miranda MC, Catanzaro NJ, Hubbard ML, Addetia A, Stewart C, Brown JT, Dosey A, Valdez A, Ravichandran R, Hendricks GG, Ahlrichs M, Dobbins C, Hand A, Treichel C, Willoughby I, Walls AC, McGuire AT, Leaf EM, Baric RS, Schäfer A, Veesler D, King NP. Chao CW, et al. Among authors: addetia a. bioRxiv [Preprint]. 2024 Mar 14:2024.03.13.584735. doi: 10.1101/2024.03.13.584735. bioRxiv. 2024. Update in: Cell Rep. 2024 Dec 24;43(12):115036. doi: 10.1016/j.celrep.2024.115036 PMID: 38558973 Free PMC article. Updated. Preprint.
Mapping immunodominant sites on the MERS-CoV spike glycoprotein targeted by infection-elicited antibodies in humans.
Addetia A, Stewart C, Seo AJ, Sprouse KR, Asiri AY, Al-Mozaini M, Memish ZA, Alshukairi A, Veesler D. Addetia A, et al. bioRxiv [Preprint]. 2024 Apr 2:2024.03.31.586409. doi: 10.1101/2024.03.31.586409. bioRxiv. 2024. Update in: Cell Rep. 2024 Aug 27;43(8):114530. doi: 10.1016/j.celrep.2024.114530 PMID: 38617298 Free PMC article. Updated. Preprint.
59 results