Pierrillas PB - Search Results

1

Modeling of Parkinson's Disease Progression and Implications for Detection of Disease Modification in Treatment Trials.

Ribba B, Simuni T, Marek K, Siderowf A, Diack C, Pierrillas PB, Monnet A, Ricci B, Nikolcheva T, Pagano G. Ribba B, et al. Among authors: pierrillas pb. J Parkinsons Dis. 2024;14(6):1225-1235. doi: 10.3233/JPD-230446. J Parkinsons Dis. 2024. PMID: 39058452 Free PMC article.

2

Population PK and Semimechanistic PK/PD Modeling and Simulation of Relugolix Effects on Testosterone Suppression in Men with Prostate Cancer.

Lee TY, Pierrillas PB, Lin YW, de Greef R, Zandvliet AS, Schindler E, Migoya E. Lee TY, et al. Among authors: pierrillas pb. Clin Pharmacol Ther. 2023 Jan;113(1):124-134. doi: 10.1002/cpt.2743. Epub 2022 Oct 18. Clin Pharmacol Ther. 2023. PMID: 36073238 Free PMC article.

3

Population pharmacokinetics of mobocertinib in healthy volunteers and patients with non-small cell lung cancer.

Gupta N, Pierrillas PB, Hanley MJ, Zhang S, Diderichsen PM. Gupta N, et al. Among authors: pierrillas pb. CPT Pharmacometrics Syst Pharmacol. 2022 Jun;11(6):731-744. doi: 10.1002/psp4.12785. Epub 2022 Apr 11. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 35316867 Free PMC article. Clinical Trial.

4

Translational approach from preclinical to clinical: comparison of dose finding methods of a new Bcl2 inhibitor using PK-PD modeling and interspecies extrapolation.

Pierrillas PB, Henin E, Ogier J, Amiel M, Kraus-Berthier L, Chenel M, Bouzom F, Tod M. Pierrillas PB, et al. Invest New Drugs. 2020 Dec;38(6):1796-1806. doi: 10.1007/s10637-020-00953-y. Epub 2020 May 25. Invest New Drugs. 2020. PMID: 32451663

5

Prediction of Human Nonlinear Pharmacokinetics of a New Bcl-2 Inhibitor Using PBPK Modeling and Interspecies Extrapolation Strategy.

Pierrillas PB, Henin E, Ball K, Ogier J, Amiel M, Kraus-Berthier L, Chenel M, Bouzom F, Tod M. Pierrillas PB, et al. Drug Metab Dispos. 2019 Jun;47(6):648-656. doi: 10.1124/dmd.118.085605. Epub 2019 Apr 2. Drug Metab Dispos. 2019. PMID: 30940629

6

Tumor Growth Inhibition Modelling Based on Receptor Occupancy and Biomarker Activity of a New Bcl-2 Inhibitor in Mice.

Pierrillas PB, Henin E, Ogier J, Kraus-Berthier L, Chenel M, Bouzom F, Tod M. Pierrillas PB, et al. J Pharmacol Exp Ther. 2018 Dec;367(3):414-424. doi: 10.1124/jpet.118.251694. Epub 2018 Sep 18. J Pharmacol Exp Ther. 2018. PMID: 30228112

7

Correction to: Model-Based Adaptive Optimal Design (MBAOD) Improves Combination Dose Finding Designs: an Example in Oncology.

Pierrillas PB, Fouliard S, Chenel M, Hooker AC, Friberg LE, Karlsson MO. Pierrillas PB, et al. AAPS J. 2018 Mar 27;20(3):55. doi: 10.1208/s12248-018-0218-5. AAPS J. 2018. PMID: 29589158

8

Model-Based Adaptive Optimal Design (MBAOD) Improves Combination Dose Finding Designs: an Example in Oncology.

Pierrillas PB, Fouliard S, Chenel M, Hooker AC, Friberg LE, Karlsson MO. Pierrillas PB, et al. AAPS J. 2018 Mar 7;20(2):39. doi: 10.1208/s12248-018-0206-9. AAPS J. 2018. PMID: 29516207

9

Improvement of Parameter Estimations in Tumor Growth Inhibition Models on Xenografted Animals: Handling Sacrifice Censoring and Error Caused by Experimental Measurement on Larger Tumor Sizes.

Pierrillas PB, Tod M, Amiel M, Chenel M, Henin E. Pierrillas PB, et al. AAPS J. 2016 Sep;18(5):1262-1272. doi: 10.1208/s12248-016-9936-8. Epub 2016 Jun 21. AAPS J. 2016. PMID: 27329303

10

Improvement of Parameter Estimations in Tumor Growth Inhibition Models on Xenografted Animals: a Novel Method to Handle the Interval Censoring Caused by Measurement of Smaller Tumors.

Pierrillas PB, Tod M, Amiel M, Chenel M, Henin E. Pierrillas PB, et al. AAPS J. 2016 Mar;18(2):404-15. doi: 10.1208/s12248-015-9862-1. Epub 2016 Jan 12. AAPS J. 2016. PMID: 26757730 Free PMC article.

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